World's Best Scientists 2026 revealed!
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Biology and Biochemistry
USA
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
163
Citations
91122
World Ranking
109
National Ranking
83

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award

Overview

Jeffrey A Whitsett is affiliated with Cincinnati Children's Hospital Medical Center in the United States and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work focuses on several subfields, including Molecular Biology, Pulmonary and Respiratory Medicine, Surgery, Epidemiology, and Cancer Research.

The scientist's research covers a range of topics such as Neonatal Respiratory Health Research, Congenital Diaphragmatic Hernia Studies, Renal and related cancers, Single-cell and spatial transcriptomics, Respiratory viral infections research, Congenital heart defects research, and Tissue Engineering and Regenerative Medicine.

Among Jeffrey A Whitsett's notable recent publications are the following:

  • An integrated cell atlas of the lung in health and disease, 2023, Nature Medicine
  • Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19, 2020, Immunity
  • The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future, 2020, Cell stem cell
  • Guided construction of single cell reference for human and mouse lung, 2023, Nature Communications
  • Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell, 2020, American Journal of Respiratory and Critical Care Medicine

Frequent co-authors collaborating with Jeffrey A Whitsett include:

  • Minzhe Guo (26 publications)
  • Yan Xu (20 publications)
  • Joseph A. Kitzmiller (18 publications)
  • William J. Zacharias (11 publications)
  • Vladimir V. Kalinichenko (11 publications)

The scientist regularly publishes work in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory) with 14 publications
  • American Journal of Respiratory Cell and Molecular Biology with 8 publications
  • American Journal of Respiratory and Critical Care Medicine with 7 publications
  • Nature Communications with 5 publications
  • iScience with 2 publications

Best Publications

  • SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

    Carly G.K. Ziegler;Samuel J. Allon;Sarah K. Nyquist;Ian M. Mbano

  • Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis

    Glenn Dranoff;Alexander D. Crawford;Michel Sadelain;Beverly Ream

  • A Mutation in the Surfactant Protein C Gene Associated with Familial Interstitial Lung Disease

    Lawrence M. Nogee;Alston E. Dunbar;Susan E. Wert;Frederic Askin

  • Pulmonary Alveolar Proteinosis

    Bruce C. Trapnell;Jeffrey A. Whitsett;Koh Nakata

  • Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function.

    Brigid L.M. Hogan;Christina E. Barkauskas;Harold A. Chapman;Jonathan A. Epstein

  • Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.

    T J Gregory;W J Longmore;M A Moxley;J A Whitsett

  • Respiratory epithelial cells orchestrate pulmonary innate immunity

    Jeffrey A Whitsett;Theresa Alenghat

  • Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice

    Jean C. Clark;Susan E. Wert;Cindy J. Bachurski;Mildred T. Stahlman

  • The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis.

    R J Bohinski;R Di Lauro;J A Whitsett

  • ABCA3 gene mutations in newborns with fatal surfactant deficiency.

    Sergey Shulenin;Lawrence M. Nogee;Tarmo Annilo;Susan E. Wert

  • Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

    Galen H. Fisher;Shari L. Wellen;David Klimstra;Joi M. Lenczowski

  • GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.

    Yoko Shibata;Pierre Yves Berclaz;Zissis C. Chroneos;Mitsuhiro Yoshida

  • Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung.

    K. Peters;S. Werner;Xiang Liao;S. Wert

  • Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice.

    Susan E. Wert;Mitsuhiro Yoshida;Ann Marie LeVine;Machiko Ikegami

  • Serial Changes in Surfactant-associated Proteins in Lung and Serum before and after Onset of ARDS

    Kelly E. Greene;Jo Rae Wright;Kenneth P. Steinberg;John T. Ruzinski

  • Interleukin-1β Causes Pulmonary Inflammation, Emphysema, and Airway Remodeling in the Adult Murine Lung

    Urpo Lappalainen;Jeffrey A. Whitsett;Susan E. Wert;Jay W. Tichelaar

  • Early restriction of peripheral and proximal cell lineages during formation of the lung.

    Anne Karina T. Perl;Susan E. Wert;Andras Nagy;Corrinne G. Lobe

  • Alveolar Surfactant Homeostasis and the Pathogenesis of Pulmonary Disease

    Jeffrey A. Whitsett;Susan E. Wert;Timothy E. Weaver

  • Transcriptional Control of Lung Morphogenesis

    Yutaka Maeda;Vrushank Davé;Jeffrey A. Whitsett

  • The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung

    Francis X. McCormack;Jeffrey A. Whitsett

Frequent Co-Authors

Thomas R. Korfhagen
Thomas R. Korfhagen Cincinnati Children's Hospital Medical Center
Machiko Ikegami
Machiko Ikegami University of Cincinnati
Bruce C. Trapnell
Bruce C. Trapnell Cincinnati Children's Hospital Medical Center
Yan Xu
Yan Xu Cincinnati Children's Hospital Medical Center
Alan H. Jobe
Alan H. Jobe Cincinnati Children's Hospital Medical Center
Francis X. McCormack
Francis X. McCormack University of Cincinnati
Barry R. Stripp
Barry R. Stripp Cedars-Sinai Medical Center
Susan E. Wert
Susan E. Wert Cincinnati Children's Hospital Medical Center
Robert P. Baughman
Robert P. Baughman University of Cincinnati
S. Steven Potter
S. Steven Potter Cincinnati Children's Hospital Medical Center

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