Jeffrey A. Whitsett mostly deals with Lung, Molecular biology, Immunology, Pathology and Pulmonary surfactant. His Lung research incorporates elements of Cell biology, Microbiology, Respiratory system and Lung morphogenesis. His studies deal with areas such as Mutation, Transgene, Gene expression, Gene and Surfactant homeostasis as well as Molecular biology.
His research investigates the connection between Immunology and topics such as Endocrinology that intersect with issues in FOXA1. His Pathology study combines topics from a wide range of disciplines, such as Pulmonary pathology, Respiratory disease, CXCL1 and Fetus. He has included themes like Bronchoalveolar lavage and Phospholipid in his Pulmonary surfactant study.
His scientific interests lie mostly in Lung, Molecular biology, Immunology, Pulmonary surfactant and Pathology. His studies in Lung integrate themes in fields like Lung morphogenesis, Respiratory system and Cell biology. In his research, Transcription factor is intimately related to Gene expression, which falls under the overarching field of Molecular biology.
Jeffrey A. Whitsett interconnects Lung injury and Surfactant protein C in the investigation of issues within Immunology. His Pulmonary surfactant research includes themes of Internal medicine, Phospholipid and Endocrinology. His Pathology research is multidisciplinary, incorporating elements of Fetus, Cancer research and Interstitial lung disease.
The scientist’s investigation covers issues in Lung, Immunology, Cell biology, Cancer research and Pathology. He combines subjects such as Transcription factor, Gene expression, Glucocorticoid receptor and Respiratory system with his study of Lung. The Immunology study combines topics in areas such as Metaplasia and Goblet cell.
His study in Cell biology is interdisciplinary in nature, drawing from both Embryonic stem cell, Lung morphogenesis, Cellular differentiation and Pulmonary surfactant, Alveolar type. Jeffrey A. Whitsett has researched Lung morphogenesis in several fields, including Transgene, Mesenchymal cell differentiation, Function, Systems biology and Molecular biology. His biological study spans a wide range of topics, including Surfactant homeostasis, Lipid Transport and Alveolar Epithelium.
Jeffrey A. Whitsett mainly investigates Lung, Immunology, Goblet cell, Cell biology and Metaplasia. His Lung study combines topics in areas such as Cancer research, Homeostasis, Pathology, Respiratory distress and Respiratory system. The study incorporates disciplines such as breakpoint cluster region, RNA-Seq and Megakaryocyte in addition to Immunology.
His Goblet cell research is multidisciplinary, incorporating perspectives in Respiratory epithelium, Meibomian gland, Eyelid, Inflammation and Respiratory Mucosa. The various areas that Jeffrey A. Whitsett examines in his Cell biology study include Transcriptional regulation, Pulmonary surfactant, Cell cycle, Regulation of gene expression and AP-1 transcription factor. Pulmonary surfactant is the subject of his research, which falls under Biochemistry.
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A Mutation in the Surfactant Protein C Gene Associated with Familial Interstitial Lung Disease
Lawrence M. Nogee;Alston E. Dunbar;Susan E. Wert;Frederic Askin.
The New England Journal of Medicine (2001)
Pulmonary Alveolar Proteinosis
Bruce C. Trapnell;Jeffrey A. Whitsett;Koh Nakata.
The New England Journal of Medicine (2003)
The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis.
R J Bohinski;R Di Lauro;J A Whitsett.
Molecular and Cellular Biology (1994)
Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.
T J Gregory;W J Longmore;M A Moxley;J A Whitsett.
Journal of Clinical Investigation (1991)
Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice
Jean C. Clark;Susan E. Wert;Cindy J. Bachurski;Mildred T. Stahlman.
Proceedings of the National Academy of Sciences of the United States of America (1995)
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes
Galen H. Fisher;Shari L. Wellen;David Klimstra;Joi M. Lenczowski.
Genes & Development (2001)
ABCA3 gene mutations in newborns with fatal surfactant deficiency.
Sergey Shulenin;Lawrence M. Nogee;Tarmo Annilo;Susan E. Wert.
The New England Journal of Medicine (2004)
Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice.
Susan E. Wert;Mitsuhiro Yoshida;Ann Marie LeVine;Machiko Ikegami.
Proceedings of the National Academy of Sciences of the United States of America (2000)
GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.
Yoko Shibata;Pierre Yves Berclaz;Zissis C. Chroneos;Mitsuhiro Yoshida.
Serial Changes in Surfactant-associated Proteins in Lung and Serum before and after Onset of ARDS
Kelly E. Greene;Jo Rae Wright;Kenneth P. Steinberg;John T. Ruzinski.
American Journal of Respiratory and Critical Care Medicine (1999)
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