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D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
15310
World Ranking
7482
National Ranking
3409

Overview

Thomas R. Korfhagen is affiliated with Cincinnati Children's Hospital Medical Center in the United States. Their research primarily focuses on areas within biochemistry, genetics, and molecular biology, with specific attention to molecular biology and pulmonary and respiratory medicine. The scientist's work encompasses topics such as neonatal respiratory health research, congenital heart defects research, and renal and related cancers.

Korfhagen has coauthored research with several frequent collaborators, including Sheng Xia, Heather Menden, Nick Townley, Sherry M. Mabry, and Jeffrey Johnston.

Key recent publications include the following:

  • Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung, 2021, JCI Insight
  • Foxa3 Induces Goblet Cell Metaplasia and Inhibits Innate Antiviral Immunity, 2020, UNC Libraries
  • Increased susceptibility of purinergic receptor-deficient mice to lung infection with Pseudomonas aeruginosa, 2025, UNC Libraries

Korfhagen's work has appeared predominantly in venues like UNC Libraries and JCI Insight, with multiple publications in both. This reflects a research output that spans both institutional repositories and peer-reviewed journals.

Best Publications

  • Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice.

    Susan E. Wert;Mitsuhiro Yoshida;Ann Marie LeVine;Machiko Ikegami

  • Altered surfactant function and structure in SP-A gene targeted mice

    Thomas R. Korfhagen;Michael D. Bruno;Gary F. Ross;Karen M. Huelsman

  • Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung.

    Ann Marie LeVine;Jeffrey A. Whitsett;Jodie A. Gwozdz;Theresa R. Richardson

  • Surfactant protein A-deficient mice are susceptible to group B streptococcal infection.

    A M LeVine;M D Bruno;K M Huelsman;G F Ross

  • SURFACTANT PROTEIN-A-DEFICIENT MICE ARE SUSCEPTIBLE TO PSEUDOMONAS AERUGINOSA INFECTION

    Ann Marie LeVine;Kim E. Kurak;Michael D. Bruno;James M. Stark

  • Surfactant Protein-D Regulates Surfactant Phospholipid Homeostasis in Vivo

    Thomas R. Korfhagen;Vladimir Sheftelyevich;Michael S. Burhans;Michael D. Bruno

  • Transcriptional Elements from the Human SP-C Gene Direct Expression in the Primordial Respiratory Epithelium of Transgenic Mice

    Susan E. Wert;Stephan W. Glasser;Thomas R. Korfhagen;Jeffrey A. Whitsett

  • SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

    Gang Chen;Thomas R. Korfhagen;Yan Xu;Joseph Kitzmiller

  • Surfactant protein-A enhances respiratory syncytial virus clearance in vivo.

    Ann Marie LeVine;Jodie Gwozdz;James M Stark;Michael Bruno

  • Lung Cell-specific Expression of the Murine Surfactant Protein A (SP-A) Gene Is Mediated by Interactions between the SP-A Promoter and Thyroid Transcription Factor-1

    Michael D. Bruno;Robert J. Bohinski;Karen M. Huelsman;Jeffrey A. Whitsett

  • Surfactant Protein D Enhances Clearance of Influenza A Virus from the Lung In Vivo

    Ann Marie LeVine;Jeffrey A. Whitsett;Kevan L. Hartshorn;Erika C. Crouch

  • Altered stability of pulmonary surfactant in SP-C-deficient mice

    Stephan W. Glasser;Michael S. Burhans;Thomas R. Korfhagen;Cheng Lun Na

  • SPDEF regulates goblet cell hyperplasia in the airway epithelium.

    Kwon-Sik Park;Thomas R. Korfhagen;Michael D. Bruno;Joseph A. Kitzmiller

  • Synthesis and processing of the precursor for human mangano-superoxide dismutase.

    Jonathan R. Wispe;Jean C. Clark;Michael S. Burhans;Keith E. Kropp

  • Surfactant Protein-A Binds Group B Streptococcus Enhancing Phagocytosis and Clearance from Lungs of Surfactant Protein-A–Deficient Mice

    Ann Marie LeVine;Kim E. Kurak;Jo Rae Wright;Wendy T. Watford

  • Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo

    Paul Borron;J. Clarke McIntosh;Thomas R. Korfhagen;Jeffrey A. Whitsett

  • Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.

    T R Korfhagen;R J Swantz;S E Wert;J M McCarty

  • Acute lung injury: functional genomics and genetic susceptibility.

    George D. Leikauf;George D. Leikauf;Susan A. McDowell;Susan A. McDowell;Scott C. Wesselkamper;Scott C. Wesselkamper;William D. Hardie;William D. Hardie

  • Surfactant Protein-D Enhances Phagocytosis and Pulmonary Clearance of Respiratory Syncytial Virus

    Ann Marie LeVine;James Elliott;Jeffrey A. Whitsett;Anon Srikiatkhachorn

  • Surfactant protein D regulates NF-kappa B and matrix metalloproteinase production in alveolar macrophages via oxidant-sensitive pathways.

    Mitsuhiro Yoshida;Thomas R. Korfhagen;Jeffrey A. Whitsett

Frequent Co-Authors

jeffrey a whitsett
jeffrey a whitsett Cincinnati Children's Hospital Medical Center
Machiko Ikegami
Machiko Ikegami University of Cincinnati
George D. Leikauf
George D. Leikauf University of Pittsburgh
Francis X. McCormack
Francis X. McCormack University of Cincinnati
Peter D. Sly
Peter D. Sly University of Queensland
Gurjit K. Khurana Hershey
Gurjit K. Khurana Hershey Cincinnati Children's Hospital Medical Center
Jo Rae Wright
Jo Rae Wright Duke University
Yan Xu
Yan Xu Cincinnati Children's Hospital Medical Center
Mario Medvedovic
Mario Medvedovic University of Cincinnati
Maureen A. Sartor
Maureen A. Sartor University of Michigan–Ann Arbor

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