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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
11632
World Ranking
10413
National Ranking
4519

Overview

George D. Leikauf is affiliated with the University of Pittsburgh in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with notable contributions also spanning subfields such as Molecular Biology, Immunology, Pulmonary and Respiratory Medicine, Oncology, and Cancer Research.

The research of George D. Leikauf addresses key topics including:

  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Asthma and respiratory diseases
  • Heme Oxygenase-1 and Carbon Monoxide
  • Air Quality and Health Impacts
  • Energy and Environment Impacts
  • Noise Effects and Management

Several recent publications demonstrate the scope of their work:

  • Mechanisms of ultrafine particle-induced respiratory health effects, 2020, Experimental & Molecular Medicine
  • Lipopolysaccharide-Mediated Chronic Inflammation Promotes Tobacco Carcinogen-Induced Lung Cancer and Determines the Efficacy of Immunotherapy, 2020, Cancer Research
  • Antimicrobial and Anti-Inflammatory Activity of Apple Polyphenol Phloretin on Respiratory Pathogens Associated With Chronic Obstructive Pulmonary Disease, 2021, Frontiers in Cellular and Infection Microbiology
  • Genetic determinants of ammonia-induced acute lung injury in mice, 2020, American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Phloretin, an Apple Polyphenol, Inhibits Pathogen-Induced Mucin Overproduction, 2020, Molecular Nutrition & Food Research

George D. Leikauf collaborates frequently with other researchers, including:

  • Kiflai Bein
  • Y. Peter Di
  • Rahel L. Birru
  • Heather Wells
  • An-Soo Jang

Their publications are distributed across several scientific journals, with recurrent contributions to:

  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Experimental & Molecular Medicine
  • Cancer Research
  • Frontiers in Cellular and Infection Microbiology
  • Journal of Asthma

The body of work by George D. Leikauf reflects an interdisciplinary approach combining molecular biology techniques and clinical insights to study respiratory diseases, inflammation, cancer immunotherapy, and environmental health impacts.

Best Publications

  • Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

    Donald G. Phinney;Michelangelo Di Giuseppe;Joel Njah;Ernest Sala

  • Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma.

    James J. Lee;Michael P. McGarry;Steven C. Farmer;Karen L. Denzler

  • O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans

    J. Seltzer;B. G. Bigby;M. Stulbarg;M. J. Holtzman

  • Hazardous Air Pollutants and Asthma

    George D Leikauf

  • Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments

    Maureen A Sartor;Craig R Tomlinson;Scott C Wesselkamper;Siva Sivaganesan

  • Airway hyperresponsiveness induced by platelet-activating factor: role of thromboxane generation.

    K F Chung;H Aizawa;G D Leikauf;I F Ueki

  • Acute lung injury: functional genomics and genetic susceptibility.

    George D. Leikauf;George D. Leikauf;Susan A. McDowell;Susan A. McDowell;Scott C. Wesselkamper;Scott C. Wesselkamper;William D. Hardie;William D. Hardie

  • Mechanisms of ultrafine particle-induced respiratory health effects

    George D. Leikauf;Sang Heon Kim;An Soo Jang

  • Leukotriene B4 induces airway hyperresponsiveness in dogs.

    P. M. O'Byrne;G. D. Leikauf;H. Aizawa;R. A. Bethel

  • Regulation of human airway mucins by acrolein and inflammatory mediators.

    Michael T. Borchers;Michael P. Carty;George D. Leikauf

  • Acrolein – a pulmonary hazard

    Kiflai Bein;George D. Leikauf

  • LRpath: a logistic regression approach for identifying enriched biological groups in gene expression data.

    Maureen A. Sartor;George D. Leikauf;Mario Medvedovic

  • Significance of thromboxane generation in ozone-induced airway hyperresponsiveness in dogs.

    H. Aizawa;K. F. Chung;G. D. Leikauf;I. Ueki

  • Microarrays as Cancer Keys: An Array of Possibilities

    Steve Mohr;George D. Leikauf;Gérard Keith;Bertrand H. Rihn

  • Sustained increase in intracellular free calcium and activation of cyclooxygenase-2 expression in mouse hepatoma cells treated with dioxin.

    Alvaro Puga;Amy Hoffer;Shaoying Zhou;Jeanne M Bohm

  • Metalloproteinases Mediate Mucin 5AC Expression by Epidermal Growth Factor Receptor Activation

    Hitesh S. Deshmukh;Lisa M. Case;Scott C. Wesselkamper;Michael T. Borchers

  • Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis.

    Daren L. Knoell;Mark W. Julian;Shengying Bao;Beth Besecker

  • Bradykinin stimulates Cl secretion and prostaglandin E2 release by canine tracheal epithelium

    G. D. Leikauf;I. F. Ueki;J. A. Nadel;J. H. Widdicombe

  • Acrolein-Activated Matrix Metalloproteinase 9 Contributes to Persistent Mucin Production

    Hitesh S. Deshmukh;Colleen Shaver;Lisa M. Case;Maggie Dietsch

  • Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma

    J. J. Lee;M. P. McGarry;S. C. Farmer;K. L. Denzler

Frequent Co-Authors

Mario Medvedovic
Mario Medvedovic University of Cincinnati
Thomas R. Korfhagen
Thomas R. Korfhagen Cincinnati Children's Hospital Medical Center
Naftali Kaminski
Naftali Kaminski Yale University
Maureen A. Sartor
Maureen A. Sartor University of Michigan–Ann Arbor
Holger Schulz
Holger Schulz Universität Hamburg
Jay A. Nadel
Jay A. Nadel University of California, San Francisco
Bruce R. Pitt
Bruce R. Pitt University of Pittsburgh
Ming You
Ming You Medical College of Wisconsin
Morton Lippmann
Morton Lippmann New York University
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center

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