James J. Lee

Overview

Best Publications

• Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

  Hadi Valadi;Karin Ekström;Apostolos Bossios;Margareta Sjöstrand

  14317
  Citations

• Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

  Shida Yousefi;Jeffrey A. Gold;Nicola Andina;James J. Lee

  1121
  Citations

• Primary structure, gene organization and polypeptide expression of poliovirus RNA

  Naomi Kitamura;Bert L. Semler;Paul G. Rothberg;Glenn R. Larsen

  1069
  Citations

• Defining a link with asthma in mice congenitally deficient in eosinophils.

  James J. Lee;Dawn Dimina;Mi Mi P. Macias;Sergei I. Ochkur

  871
  Citations

• Eosinophils are required for the maintenance of plasma cells in the bone marrow

  Van Trung Chu;Anja Fröhlich;Gudrun Steinhauser;Tobias Scheel

  680
  Citations

• Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma.

  James J. Lee;Michael P. McGarry;Steven C. Farmer;Karen L. Denzler

  608
  Citations

• A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species.

  Marie Luise Brennan;Weijia Wu;Xiaoming Fu;Zhongzhu Shen

  496
  Citations

• Fundamental signals that regulate eosinophil homing to the gastrointestinal tract

  Anil Mishra;Simon P. Hogan;James J. Lee;Paul S. Foster

  461
  Citations

• Eosinophils in health and disease: The LIAR hypothesis

  James J. Lee;Elizabeth A. Jacobsen;Michael P. McGarry;Robert P. Schleimer

  377
  Citations

• Adenomatous Polyps Are Driven by Microbe-Instigated Focal Inflammation and Are Controlled by IL-10–Producing T Cells

  Kristen L. Dennis;Yunwei Wang;Nichole R. Blatner;Shuya Wang

  351
  Citations

• Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults With Eosinophilic Esophagitis

  Ekaterina Safroneeva;Alex Straumann;Alex Straumann;Michael Coslovsky;Marcel Zwahlen

  309
  Citations

• Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization.

  E Hamelmann;A Oshiba;J Loader;G L Larsen

  297
  Citations

• Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells

  Elizabeth A. Jacobsen;Sergei I. Ochkur;Ralph S. Pero;Anna G. Taranova

  294
  Citations

• Expression of IL-5 in thymocytes/T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies.

  Nancy A. Lee;Michael P. McGarry;Kirsten A. Larson;Margaret A. Horton

  280
  Citations

• The oesophageal string test: a novel, minimally invasive method measures mucosal inflammation in eosinophilic oesophagitis

  Glenn T. Furuta;Amir F. Kagalwalla;James J. Lee;Preeth Alumkal

  278
  Citations

• The expanding role(s) of eosinophils in health and disease

  Elizabeth A. Jacobsen;Richard A. Helmers;James J. Lee;Nancy A. Lee

  260
  Citations

• Metabolic Consequences of Adenosine Deaminase Deficiency in Mice Are Associated with Defects in Alveogenesis, Pulmonary Inflammation, and Airway Obstruction

  Michael R. Blackburn;Jonathan B. Volmer;Janci L. Thrasher;Hongyan Zhong

  259
  Citations

• The Construction of Transgenic and Gene Knockout/Knockin Mouse Models of Human Disease

  Alfred Doyle;Michael P. McGarry;Nancy A. Lee;James J. Lee

  257
  Citations

• Eosinophils: singularly destructive effector cells or purveyors of immunoregulation?

  Elizabeth A. Jacobsen;Anna G. Taranova;Nancy A. Lee;James J. Lee

  247
  Citations

• The late, but not early, asthmatic response is dependent on IL-5 and correlates with eosinophil infiltration

  Grzegorz Cieslewicz;Adrian Tomkinson;Andy Adler;Catherine Duez

  244
  Citations

• Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma

  J. J. Lee;M. P. McGarry;S. C. Farmer;K. L. Denzler

  1
  Citations