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Animal Science and Veterinary

D-Index
36
Citations
5772
World Ranking
1582
National Ranking
460

Overview

Thomas J. Nolan is affiliated with the University of Pennsylvania in the United States. Their research spans multiple areas primarily within Medicine and Immunology and Microbiology, with a notable focus on Infectious Diseases and Parasitology.

The scientist has contributed to the understanding of parasitic diseases, parasite-host interactions, and mosquito-borne diseases. Their work also touches on gut microbiota and health, insect symbiosis and bacterial influences, and public health concerns related to parasitic infections. Molecular biology approaches are part of their multidisciplinary study.

Frequent publication venues for Nolan include Parasites & Vectors, bioRxiv (Cold Spring Harbor Laboratory), mSphere, Proceedings of the National Academy of Sciences, and PLoS Pathogens.

Coauthors who have collaborated with Nolan on multiple occasions are James B. Lok, Elizabeth B. Edgerton, Abigail Mccrea, Michael Povelones, and Alexander S. F. Berry.

Notable recent papers authored by Nolan include:

  • "Natural Infection with Giardia Is Associated with Altered Community Structure of the Human and Canine Gut Microbiome" (2020, mSphere)
  • "Activation of mosquito immunity blocks the development of transmission-stage filarial nematodes" (2020, Proceedings of the National Academy of Sciences)
  • "Retrospective study of canine endoparasites diagnosed by fecal flotation methods analyzed across veterinary parasitology diagnostic laboratories, United States, 2018" (2021, Parasites & Vectors)
  • "Transgenic expression of a T cell epitope in Strongyloides ratti reveals that helminth-specific CD4+ T cells constitute both Th2 and Treg populations" (2021, PLoS Pathogens)
  • "A novel assay to isolate and quantify third-stage Dirofilaria immitis and Brugia malayi larvae emerging from individual Aedes aegypti" (2021, Parasites & Vectors)

The primary fields of study for Thomas J. Nolan are Medicine and Immunology and Microbiology, supported by focused subfields including Infectious Diseases, Parasitology, Insect Science, Public Health, Environmental and Occupational Health, and Molecular Biology.

Major research topics covered by Nolan are:

  • Parasitic Diseases Research and Treatment
  • Parasites and Host Interactions
  • Parasitic Infections and Diagnostics
  • Insect symbiosis and bacterial influences
  • Mosquito-borne diseases and control
  • Clostridium difficile and Clostridium perfringens research
  • Gut microbiota and health

Best Publications

  • Endoparasite prevalence and recurrence across different age groups of dogs and cats

    Maureen C. Gates;Thomas J. Nolan

  • Eosinophils Can Function as Antigen-Presenting Cells To Induce Primary and Secondary Immune Responses to Strongyloides stercoralis

    Udaikumar M. Padigel;James J. Lee;Thomas J. Nolan;Gerhard A. Schad

  • Role of IL-5 in innate and adaptive immunity to larval Strongyloides stercoralis in mice.

    De’Broski R. Herbert;James J. Lee;Nancy A. Lee;Thomas J. Nolan

  • Role of eosinophils and neutrophils in innate and adaptive protective immunity to larval strongyloides stercoralis in mice.

    Ann Marie Galioto;Jessica A. Hess;Thomas J. Nolan;Gerhard A. Schad

  • Extracellular traps are associated with human and mouse neutrophil and macrophage mediated killing of larval Strongyloides stercoralis

    Sandra Bonne-Année;Laura A. Kerepesi;Jessica A. Hess;Jordan Wesolowski

  • Infection of mice with the helminth Strongyloides stercoralis suppresses pulmonary allergic responses to ovalbumin

    Chun-Chi Wang;T. J. Nolan;G. A. Schad;D. Abraham

  • Eosinophils Act as Antigen-Presenting Cells to Induce Immunity to Strongyloides stercoralis in Mice

    Udaikumar M. Padigel;Jessica A. Hess;James J. Lee;James B. Lok

  • Strongyloides stercoralis: eosinophil-dependent immune-mediated killing of third stage larvae in BALB/cByJ mice.

    Harris L. Rotman;Wiboonchai Yutanawiboonchai;Richard A. Brigandi;Ofra Leon

  • Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice.

    Amy E. O'Connell;Jessica A. Hess;Gilberto A. Santiago;Thomas J. Nolan

  • Time series analysis of the prevalence of endoparasitic infections in cats and dogs presented to a veterinary teaching hospital.

    Thomas J. Nolan;Gary Smith

  • Strongyloides stercoralis: The First Rodent Model for Uncomplicated and Hyperinfective Strongyloidiasis, the Mongolian Gerbil (Meriones unguiculatus)

    Thomas J. Nolan;Zoltan Megyeri;Veena M. Bhopale;Gerhard A. Schad

  • Strongyloides stercoralis: protective immunity to third-stage larvae in BALB/cByJ mice

    D. Abraham;H.L. Rotman;H.F. Haberstroh;W. Yutanawiboonchai

  • Macrocyclic lactones in the treatment and control of parasitism in small companion animals.

    Thomas J Nolan;James B Lok

  • Human and mouse macrophages collaborate with neutrophils to kill larval Strongyloides stercoralis.

    Sandra Bonne-Année;Laura A. Kerepesi;Jessica A. Hess;Amy E. O'Connell

  • RNAseq Analysis of the Parasitic Nematode Strongyloides stercoralis Reveals Divergent Regulation of Canonical Dauer Pathways

    Jonathan D. Stoltzfus;Samuel Minot;Matthew Berriman;Thomas J. Nolan

  • IL‐12 eliminates the Th‐2 dependent protective immune response of mice to larval Strongyloides stercoralis

    H.L. Rotman;S. Schnyder-Candrian;P. Scott;T.J. Nolan

  • Specificity and mechanism of immunoglobulin M (IgM)- and IgG-dependent protective immunity to larval Strongyloides stercoralis in mice.

    Jessica A. Ligas;Laura A. Kerepesi;Ann Marie Galioto;Sara Lustigman

  • Successful transgenesis of the parasitic nematode Strongyloides stercoralis requires endogenous non-coding control elements

    Xinshe Li;Holman C. Massey;Thomas J. Nolan;Gerhard A. Schad

  • The role of B cells in immunity against larval Strongyloides stercoralis in mice.

    De’broski R. Herbert;Thomas J. Nolan;Gerhard A. Schad;David Abraham

  • Strongyloides stercoralis: cell- and tissue-specific transgene expression and co-transformation with vector constructs incorporating a common multifunctional 3' UTR.

    Ariel B. Junio;Xinshe Li;Holman C. Massey;Thomas J. Nolan

  • Strongyloides stercoralis : Role of antibody and complement in immunity to the third stage larvae in BALB/cByJ mice

    Richard A. Brigandi;Harris L. Rotman;Wiboonchai Yutanawiboonchai;Ofra Leon

  • Transposon-mediated Chromosomal Integration of Transgenes in the Parasitic Nematode Strongyloides ratti and Establishment of Stable Transgenic Lines

    Hongguang Shao;Xinshe Li;Thomas J Nolan;Holman C Massey

  • Complement Component C3 Is Required for Protective Innate and Adaptive Immunity to Larval Strongyloides stercoralis in Mice

    Laura A. Kerepesi;Jessica A. Hess;Thomas J. Nolan;Gerhard A. Schad

Frequent Co-Authors

Gerhard A. Schad
Gerhard A. Schad University of Pennsylvania
David Abraham
David Abraham University College London
James J. Lee
James J. Lee Mayo Clinic
Sara Lustigman
Sara Lustigman New York Blood Center
Thomas B. Nutman
Thomas B. Nutman National Institute of Allergy and Infectious Diseases
Raymond C. Boston
Raymond C. Boston St Vincent's Hospital
David J. Mangelsdorf
David J. Mangelsdorf The University of Texas Southwestern Medical Center
Steven A. Kliewer
Steven A. Kliewer The University of Texas Southwestern Medical Center
Gary Smith
Gary Smith University of Pennsylvania
Anne M. Zajac
Anne M. Zajac Virginia Tech

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