Takahiro Ochiya

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award
• 2025 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

  Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  12011
  Citations

• Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

  Nobuyoshi Kosaka;Haruhisa Iguchi;Yusuke Yoshioka;Fumitaka Takeshita

  1959
  Citations

• Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

  Shin Ichiro Ohno;Masakatsu Takanashi;Katsuko Sudo;Shinobu Ueda

  1752
  Citations

• Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis.

  Nobuyoshi Kosaka;Haruhisa Iguchi;Takahiro Ochiya

  1567
  Citations

• Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper

  Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

  1451
  Citations

• Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis.

  Nobuyoshi Kosaka;Haruhisa Iguchi;Keitaro Hagiwara;Yusuke Yoshioka

  800
  Citations

• Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

  Naoomi Tominaga;Nobuyoshi Kosaka;Makiko Ono;Takeshi Katsuda

  748
  Citations

• Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes.

  Agnieszka Banas;Takumi Teratani;Yusuke Yamamoto;Makoto Tokuhara

  712
  Citations

• Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells

  Makiko Ono;Nobuyoshi Kosaka;Naoomi Tominaga;Yusuke Yoshioka

  699
  Citations

• microRNA as a new immune-regulatory agent in breast milk

  Nobuyoshi Kosaka;Hirohisa Izumi;Kazunori Sekine;Takahiro Ochiya

  611
  Citations

• Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen

  Yusuke Yoshioka;Nobuyoshi Kosaka;Yuki Konishi;Hideki Ohta

  565
  Citations

• Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes

  Takeshi Katsuda;Reiko Tsuchiya;Nobuyoshi Kosaka;Yusuke Yoshioka

  547
  Citations

• Drug Resistance Driven by Cancer Stem Cells and Their Niche.

  Marta Prieto-Vila;Ryou U. Takahashi;Wataru Usuba;Isaku Kohama

  530
  Citations

• Emerging roles of long non-coding RNA in cancer.

  Anna Sanchez Calle;Yumi Kawamura;Yusuke Yamamoto;Fumitaka Takeshita

  527
  Citations

• Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes

  Fumitaka Takeshita;Lubna Patrawala;Mitsuhiko Osaki;Ryou U. Takahashi

  510
  Citations

• Exosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer

  T Matsumura;K Sugimachi;H Iinuma;Y Takahashi

  483
  Citations

• Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo

  Fumitaka Takeshita;Yoshiko Minakuchi;Shunji Nagahara;Kimi Honma

  442
  Citations

• The therapeutic potential of mesenchymal stem cell‐derived extracellular vesicles

  Takeshi Katsuda;Nobuyoshi Kosaka;Fumitaka Takeshita;Takahiro Ochiya

  426
  Citations

• Comparative marker analysis of extracellular vesicles in different human cancer types

  Yusuke Yoshioka;Yuki Konishi;Nobuyoshi Kosaka;Takeshi Katsuda

  416
  Citations

• Applying extracellular vesicles based therapeutics in clinical trials

  Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

  5
  Citations