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Toshio Kitamura

Toshio Kitamura

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
102
Citations
47491
World Ranking
1343
National Ranking
74

Medicine

D-Index
101
Citations
47210
World Ranking
7852
National Ranking
194

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Toshio Kitamura is affiliated with the University of Tokyo in Japan and has contributed extensively to research in medicine, particularly within the fields of biochemistry, genetics, and molecular biology. The main subfields reflected in their work include molecular biology, hematology, and immunology, with additional research interests in genetics and plant science.

Their research topics prominently focus on acute myeloid leukemia, protein degradation and inhibitors, immune cell function and interaction, epigenetics and DNA methylation, chronic myeloid leukemia treatments, histone deacetylase inhibitors, and myeloproliferative neoplasms diagnosis and treatment.

Notable recent papers by Toshio Kitamura include:

  • Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway, 2021, Nature Communications
  • Clonal hematopoiesis and associated diseases: A review of recent findings, 2021, Cancer Science
  • Exit from germinal center to become quiescent memory B cells depends on metabolic reprograming and provision of a survival signal, 2020, The Journal of Experimental Medicine
  • ASXL1 mutation in clonal hematopoiesis, 2020, Experimental Hematology
  • CHIP-associated mutant ASXL1 in blood cells promotes solid tumor progression, 2022, Cancer Science

Scientific collaboration is a significant component of Kitamura's research environment. Frequent coauthors include Susumu Goyama, Shuhei Asada, Yosuke Tanaka, Tomofusa Fukuyama, and Tsuyoshi Fukushima, reflecting ongoing partnerships in their areas of study.

Their work has been published primarily in venues such as Experimental Hematology, Blood, Nature Communications, Cancer Science, and Leukemia. Experimental Hematology accounts for the largest number of their publications, followed by Blood and Nature Communications.

Best Publications

  • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

    Toshimasa Yamauchi;Junji Kamon;Yusuke Ito;Atsushi Tsuchida

  • Plat-E: an efficient and stable system for transient packaging of retroviruses.

    S Morita;T Kojima;T Kitamura

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance

    Naoto Kubota;Yasuo Terauchi;Hiroshi Miki;Hiroyuki Tamemoto;Hiroyuki Tamemoto

  • Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

    Yoshinori Nagai;Sachiko Akashi;Masakazu Nagafuku;Masato Ogata

  • Identification of Tim4 as a phosphatidylserine receptor.

    Masanori Miyanishi;Masanori Miyanishi;Kazutoshi Tada;Masato Koike;Yasuo Uchiyama

  • Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

    Toshio Kitamura;Tsuyoshi Tange;Takashi Terasawa;Shigeru Chiba

  • Human placenta-derived cells have mesenchymal stem/progenitor cell potential.

    Yumi Fukuchi;Hideaki Nakajima;Daisuke Sugiyama;Imiko Hirose

  • Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.

    Kazuhiro Hayashida;Toshio Kitamura;Daniel M. Gorman;Ken-Ichi Arai

  • Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptors

    Toshio Kitamura;Noriko Sato;Ken-ichi Arai;Atsushi Miyajima

  • Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines.

    Fumihiko Hayakawa;Masayuki Towatari;Hitoshi Kiyoi;Mitsune Tanimoto

  • Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

    Toshio Kitamura;Yuko Koshino;Fumi Shibata;Toshihiko Oki

  • DNAM-1, A Novel Adhesion Molecule Involved in the Cytolytic Function of T Lymphocytes

    Akira Shibuya;David Campbell;Charles Hannum;Hans Yssel

  • STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells

    Tetsuya Nosaka;Toshiyuki Kawashima;Kazuhide Misawa;Koichi Ikuta

  • Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

    A. L.-F. Mui;H. Wakao;T. Kinoshita;T. Kitamura

  • Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation.

    Yumiko Oishi;Ichiro Manabe;Kazuyuki Tobe;Kensuke Tsushima

  • Identification and Characterization of a Constitutively Active STAT5 Mutant That Promotes Cell Proliferation

    Mayumi Onishi;Tetsuya Nosaka;Kazuhide Misawa;Alice L.-F. Mui

  • Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation.

    K Sakamaki;I Miyajima;T Kitamura;A Miyajima

  • Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells.

    Itaru Matsumura;Toshio Kitamura;Hiroshi Wakao;Hirokazu Tanaka

  • CIS3/SOCS-3 Suppresses Erythropoietin (EPO) Signaling by Binding the EPO Receptor and JAK2 *

    Atsuo Sasaki;Hideo Yasukawa;Takanori Shouda;Toshio Kitamura

Frequent Co-Authors

Tetsuya Nosaka
Tetsuya Nosaka Mie University
Atsushi Miyajima
Atsushi Miyajima University of Tokyo
Yoshihiro Morikawa
Yoshihiro Morikawa Wakayama Medical University
Ko Okumura
Ko Okumura Juntendo University
Fumimaro Takaku
Fumimaro Takaku University of Tokyo
Arinobu Tojo
Arinobu Tojo University of Tokyo
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Juha Kere
Juha Kere Karolinska Institute

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