D-Index & Metrics Best Publications
Tetsuya Nosaka

Tetsuya Nosaka

Mie University
Japan

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

The scientist’s investigation covers issues in Cell biology, Molecular biology, Signal transduction, Cancer research and STAT5. His work on Immunology expands to the thematically related Cell biology. In his work, RNA, Signal peptide, Virus, Nucleolus and Plasmid is strongly intertwined with Cell culture, which is a subfield of Molecular biology.

His study in Signal transduction is interdisciplinary in nature, drawing from both STAT6, Fibronectin, Programmed cell death and Cellular differentiation. His biological study spans a wide range of topics, including Transcriptional regulation, Promoter, Receptor tyrosine kinase, Tumor progression and Leukemia. In his research, Mutagenesis, Mutant and Transactivation is intimately related to Tyrosine phosphorylation, which falls under the overarching field of STAT5.

His most cited work include:

  • Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. (1192 citations)
  • Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics (610 citations)
  • Defective Lymphoid Development in Mice Lacking Jak3 (580 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Molecular biology, Cell biology, Cancer research, Immunology and Virology. Tetsuya Nosaka has researched Molecular biology in several fields, including Cell culture, STAT5, Gene, Nucleolus and Virus. The concepts of his STAT5 study are interwoven with issues in STAT3 and Tyrosine phosphorylation.

His studies deal with areas such as Cellular differentiation and Cell growth as well as Cell biology. His Cancer research research is multidisciplinary, relying on both Carcinogenesis, Receptor tyrosine kinase, Janus kinase and Lymphoma. His Signal transduction research integrates issues from Regulation of gene expression, Endocrinology and Internal medicine.

He most often published in these fields:

  • Molecular biology (31.51%)
  • Cell biology (33.56%)
  • Cancer research (20.55%)

What were the highlights of his more recent work (between 2013-2021)?

  • Virology (16.44%)
  • Immunology (21.92%)
  • Vector (5.48%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Virology, Immunology, Vector, Fusion protein and Cancer research. Tetsuya Nosaka combines subjects such as Molecular biology and Transduction with his study of Virology. His work on Immune system as part of general Immunology research is often related to Streptococcus, thus linking different fields of science.

His Fusion protein research is multidisciplinary, incorporating perspectives in Amino acid, Cytoplasm, Cell biology and NLS. Tetsuya Nosaka is interested in Progenitor cell, which is a branch of Cell biology. His research integrates issues of Leukemia and Cellular differentiation in his study of Myeloid leukemia.

Between 2013 and 2021, his most popular works were:

  • A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis. (10 citations)
  • Recombinant Ag85B vaccine by taking advantage of characteristics of human parainfluenza type 2 virus vector showed Mycobacteria-specific immune responses by intranasal immunization (10 citations)
  • Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis. (9 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Immunology, Mutation, Immune system, Gene and Fusion protein are his primary areas of study. In the subject of general Immunology, his work in Exacerbation is often linked to Staphylococcus, thereby combining diverse domains of study. His study explores the link between Mutation and topics such as Cancer that cross with problems in Cancer research.

His Cancer research research is multidisciplinary, incorporating elements of Haematopoiesis, Stem cell, Cellular differentiation, Mutation testing and CD5. His study on Gene is covered under Genetics. His research in Antigen intersects with topics in Molecular biology, Nucleic acid and Peptide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene.

Kazuya Shimoda;Jan van Deursent;Mark Y. Sangster;Sally R. Sarawar.
Nature (1996)

1579 Citations

Defective Lymphoid Development in Mice Lacking Jak3

Tetsuya Nosaka;Jan M. A. van Deursen;Ralph A. Tripp;William E. Thierfelder.
Science (1995)

772 Citations

Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

Toshio Kitamura;Yuko Koshino;Fumi Shibata;Toshihiko Oki.
Experimental Hematology (2003)

765 Citations

STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells

Tetsuya Nosaka;Toshiyuki Kawashima;Kazuhide Misawa;Koichi Ikuta.
The EMBO Journal (1999)

623 Citations

Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro

Atsushi Tanaka;Chiaki Takahashi;Shoji Yamaoka;Tetsuya Nosaka.
Proceedings of the National Academy of Sciences of the United States of America (1990)

517 Citations

Identification and Characterization of a Constitutively Active STAT5 Mutant That Promotes Cell Proliferation

Mayumi Onishi;Tetsuya Nosaka;Kazuhide Misawa;Alice L.-F. Mui.
Molecular and Cellular Biology (1998)

499 Citations

Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis

Yukinori Minoshima;Toshiyuki Kawashima;Koichi Hirose;Koichi Hirose;Yukio Tonozuka.
Developmental Cell (2003)

371 Citations

Sequence requirements for nucleolar localization of human T cell leukemia virus type I pX protein, which regulates viral RNA processing

Haruhiko Siomi;Hisatoshi Shida;Seok Hyun Nam;Tetsuya Nosaka.
Cell (1988)

342 Citations

Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.

F. W. Quelle;Demin Wang;T. Nosaka;W. E. Thierfelder.
Molecular and Cellular Biology (1996)

312 Citations

MgcRacGAP Is Involved in Cytokinesis through Associating with Mitotic Spindle and Midbody

Koichi Hirose;Toshiyuki Kawashima;Itsuo Iwamoto;Tetsuya Nosaka.
Journal of Biological Chemistry (2001)

245 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Tetsuya Nosaka

Toshio Kitamura

Toshio Kitamura

University of Tokyo

Publications: 108

John J. O'Shea

John J. O'Shea

National Institutes of Health

Publications: 46

James N. Ihle

James N. Ihle

St. Jude Children's Research Hospital

Publications: 40

Warren J. Leonard

Warren J. Leonard

National Institutes of Health

Publications: 40

Demin Wang

Demin Wang

Medical College of Wisconsin

Publications: 35

Mark H. Kaplan

Mark H. Kaplan

Indiana University

Publications: 34

Richard Moriggl

Richard Moriggl

University of Veterinary Medicine Vienna

Publications: 32

Fred D. Finkelman

Fred D. Finkelman

University of Cincinnati

Publications: 30

William E. Paul

William E. Paul

National Institute of Allergy and Infectious Diseases

Publications: 29

Akihiko Yoshimura

Akihiko Yoshimura

Keio University

Publications: 29

Michael J. Grusby

Michael J. Grusby

Harvard University

Publications: 28

Kuan-Teh Jeang

Kuan-Teh Jeang

National Institutes of Health

Publications: 26

Shizuo Akira

Shizuo Akira

Osaka University

Publications: 25

Taisuke Tomita

Taisuke Tomita

University of Tokyo

Publications: 24

John N. Brady

John N. Brady

National Institutes of Health

Publications: 23

Hiroshi Nakajima

Hiroshi Nakajima

Chiba University

Publications: 22

Trending Scientists

Branko Milanovic

Branko Milanovic

City University of New York

Loretta J. Mester

Loretta J. Mester

Federal Reserve Bank of Cleveland

Robert C. Qiu

Robert C. Qiu

Shanghai Jiao Tong University

Werner-Michael Kulicke

Werner-Michael Kulicke

Universität Hamburg

George W. Kabalka

George W. Kabalka

University of Tennessee at Knoxville

Erico M.M. Flores

Erico M.M. Flores

Universidade Federal de Santa Maria

Xiaodong Cheng

Xiaodong Cheng

The University of Texas MD Anderson Cancer Center

Edward L. Tatum

Edward L. Tatum

Rockefeller University

Eran Pichersky

Eran Pichersky

University of Michigan–Ann Arbor

Brian M. Chase

Brian M. Chase

Centre national de la recherche scientifique, CNRS

Yonggang Liu

Yonggang Liu

University of South Florida St. Petersburg

Nelly Alia-Klein

Nelly Alia-Klein

Icahn School of Medicine at Mount Sinai

Paul A. Kirschner

Paul A. Kirschner

Open University in the Netherlands

Diane R. Follingstad

Diane R. Follingstad

University of Kentucky

Peter D. Gluckman

Peter D. Gluckman

University of Auckland

Bernhard O. Boehm

Bernhard O. Boehm

Nanyang Technological University

Something went wrong. Please try again later.