Taisuke Tomita

Overview

Best Publications

• APP processing and synaptic function.

  Flavio Kamenetz;Taisuke Tomita;Helen Hsieh;Helen Hsieh;Guy Seabrook

  2095
  Citations

• Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

  M. Baba;S. Nakajo;P.-H. Tu;T. Tomita

  1996
  Citations

• High performance plasma amyloid-β biomarkers for Alzheimer’s disease

  Akinori Nakamura;Naoki Kaneko;Victor L Villemagne;Takashi Kato

  1685
  Citations

• AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss.

  Helen Hsieh;Jannic Boehm;Chihiro Sato;Takeshi Iwatsubo

  1355
  Citations

• The role of presenilin cofactors in the gamma-secretase complex.

  Nobumasa Takasugi;Taisuke Tomita;Ikuo Hayashi;Makiko Tsuruoka

  1142
  Citations

• Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein

  Pang-hsien Tu;James E. Galvin;James E. Galvin;Minami Baba;Benoit Giasson

  736
  Citations

• Structures of α-synuclein filaments from multiple system atrophy

  Manuel Schweighauser;Yang Shi;Airi Tarutani;Airi Tarutani;Fuyuki Kametani

  560
  Citations

• Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating.

  King-Ho Cheung;Diana Shineman;Marioly Müller;César Cárdenas

  528
  Citations

• The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue

  Taisuke Tomita;Kei Maruyama;Takaomi C. Saido;Hideaki Kume

  527
  Citations

• Effects of PS1 Deficiency on Membrane Protein Trafficking in Neurons

  Satoshi Naruse;Gopal Thinakaran;Jin Jun Luo;John W. Kusiak

  468
  Citations

• A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling.

  Harald Steiner;Karen Duff;Anja Capell;Helmut Romig

  402
  Citations

• Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.

  Keiro Shirotani;Satoshi Tsubuki;Nobuhisa Iwata;Yoshie Takaki

  361
  Citations

• Sedation and Anesthesia Mediated by Distinct GABAA Receptor Isoforms

  David S. Reynolds;Thomas W. Rosahl;Jennifer Cirone;Gillian F. O'Meara

  342
  Citations

• Presenilins mediate a dual intramembranous γ‐secretase cleavage of Notch‐1

  Masayasu Okochi;Harald Steiner;Akio Fukumori;Hisashi Tanii

  330
  Citations

• High performance plasma amyloid-beta biomarkers for Alzheimer's disease

  Akinori Nakamura;Naoki Kaneko;Victor L Villemagne;Takashi Kato

  278
  Citations

• A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis.

  Eric H. Schroeter;Ma. Xenia G. Ilagan;Anne L. Brunkan;Silva Hecimovic

  270
  Citations

• Sulindac Sulfide Is a Noncompetitive γ-Secretase Inhibitor That Preferentially Reduces Aβ42 Generation

  Yasuko Takahashi;Ikuo Hayashi;Yusuke Tominari;Kentaro Rikimaru

  261
  Citations

• Activity-Dependent Proteolytic Cleavage of Neuroligin-1

  Kunimichi Suzuki;Yukari Hayashi;Soichiro Nakahara;Hiroshi Kumazaki

  231
  Citations

• BACE1 activity is modulated by cell-associated sphingosine-1-phosphate

  Nobumasa Takasugi;Tomoki Sasaki;Kunimichi Suzuki;Satoko Osawa

  227
  Citations

• Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease.

  Masaaki Takahashi;Sylvain Doré;Christopher D. Ferris;Taisuke Tomita

  221
  Citations