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Haruhiko Fuwa

Haruhiko Fuwa

D-Index & Metrics

Chemistry

D-Index
42
Citations
5672
World Ranking
17602
National Ranking
1392

Overview

Haruhiko Fuwa is affiliated with Chuo University in Japan and has contributed extensively to the fields of Chemistry, Materials Science, and Biochemistry, Genetics and Molecular Biology. Fuwa's research output encompasses 61 publications in Chemistry, with significant contributions to Organic Chemistry, Materials Chemistry, and Biotechnology.

Their research largely focuses on Synthetic Organic Chemistry Methods, Crystallization and Solubility Studies, and X-ray Diffraction in Crystallography. Additional topics include Marine Sponges and Natural Products, Chemical Synthesis and Alkaloids, Marine Toxins and Detection Methods, and Asymmetric Synthesis and Catalysis.

Frequent publication venues for Fuwa include The Cambridge Structural Database, where they have published 19 papers, Organic Letters and The Journal of Organic Chemistry with six papers each, the Bulletin of the Chemical Society of Japan with four publications, and Chemistry - An Asian Journal with two.

Fuwa has collaborated regularly with a core group of researchers, with notable frequent coauthors being Yuki Wada, Pavel M. Usov, Makoto Mukaida, Ken Ohmori, and Hiroyoshi Ohtsu, each appearing in 20 joint publications.

Selected recent papers illustrating Fuwa's research include:

  • Structure determination, correction, and disproof of marine macrolide natural products by chemical synthesis, 2021, Organic Chemistry Frontiers
  • Total Synthesis of (+)-Neopeltolide by the Macrocyclization/Transannular Pyran Cyclization Strategy, 2022, Organic Letters
  • Stereoselective Tandem Synthesis of Pyrrolidine Derivatives under Gold Catalysis: An Asymmetric Synthesis of (−)-Lepadiformine A, 2022, Organic Letters
  • Atomic-resolution structure analysis inside an adaptable porous framework, 2024, Nature Communications
  • Determination of the toxicity equivalency factors for ciguatoxins using human sodium channels, 2022, Food and Chemical Toxicology

Best Publications

  • Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling

    Masahiro Sonoshita;Masahiro Aoki;Haruhiko Fuwa;Koji Aoki

  • Total Synthesis of Gambierol

    Haruhiko Fuwa;Noriko Kainuma;Kazuo Tachibana;Makoto Sasaki

  • C-terminal fragment of presenilin is the molecular target of a dipeptidic γ-secretase-specific inhibitor DAPT (N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine T-butyl ester

    Yuichi Morohashi;Toshiyuki Kan;Yusuke Tominari;Haruhiko Fuwa

  • Total synthesis, structure revision, and absolute configuration of (-)-brevenal.

    Haruhiko Fuwa;Makoto Ebine;Andrea J. Bourdelais;Daniel G. Baden

  • New strategy for convergent synthesis of trans-fused polyether frameworks based on palladium-catalyzed suzuki cross-coupling reaction

    Makoto Sasaki;Haruhiko Fuwa;Masayuki Inoue;Kazuo Tachibana

  • A General Method for Convergent Synthesis of Polycyclic Ethers Based on Suzuki Cross-Coupling: Concise Synthesis of the ABCD Ring System of Ciguatoxin

    Makoto Sasaki;Haruhiko Fuwa;Makoto Ishikawa;Kazuo Tachibana

  • A Concise Total Synthesis of (+)‐Neopeltolide

    Haruhiko Fuwa;Asami Saito;Makoto Sasaki

  • Divergent synthesis of multifunctional molecular probes to elucidate the enzyme specificity of dipeptidic γ-secretase inhibitors

    Haruhiko Fuwa;Yasuko Takahashi;Yu Konno;Naoto Watanabe

  • Total synthesis of (+)-neopeltolide

    Haruhiko Fuwa;Shinya Naito;Tomomi Goto;Makoto Sasaki

  • Total Synthesis of Polycyclic Ether Natural Products Based on Suzuki-Miyaura Cross-Coupling

    Makoto Sasaki;Haruhiko Fuwa

  • Convergent strategies for the total synthesis of polycyclic ether marine metabolites.

    Makoto Sasaki;Haruhiko Fuwa

  • A general strategy for the convergent synthesis of fused polycyclic ethers via B-alkyl Suzuki coupling: synthesis of the ABCD ring fragment of ciguatoxins

    Makoto Sasaki;Makoto Sasaki;Makoto Ishikawa;Haruhiko Fuwa;Kazuo Tachibana

  • A unified total synthesis of aspergillides A and B.

    Haruhiko Fuwa;Hiroshi Yamaguchi;Makoto Sasaki

  • Stereoselective synthesis of substituted tetrahydropyrans via domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization.

    Haruhiko Fuwa;Kenkichi Noto;Makoto Sasaki

  • Synthetic studies on a marine polyether toxin, gambierol: stereoselective synthesis of the FGH ring system via B-alkyl Suzuki coupling

    Haruhiko Fuwa;Makoto Sasaki;Kazuo Tachibana

  • Total synthesis of gambierol.

    Haruhiko Fuwa;Makoto Sasaki;Masayuki Satake;Kazuo Tachibana

  • Inhibition of voltage-gated potassium currents by gambierol in mouse taste cells.

    Valeria Ghiaroni;Makoto Sasaki;Haruhiko Fuwa;Gian Paolo Rossini

  • Total synthesis and biological evaluation of (+)-neopeltolide and its analogues.

    Haruhiko Fuwa;Asami Saito;Shinya Naito;Keiichi Konoki

  • Total synthesis and biological assessment of (-)-exiguolide and analogues.

    Haruhiko Fuwa;Takaya Suzuki;Hiroshi Kubo;Takao Yamori

  • Stereoselective Synthesis of 2,6-Cis-Substituted Tetrahydropyrans: Brønsted Acid-Catalyzed Intramolecular Oxa-Conjugate Cyclization of α,β-Unsaturated Ester Surrogates

    Haruhiko Fuwa;Naoki Ichinokawa;Kenkichi Noto;Makoto Sasaki

  • Strategies for the synthesis of 2-substituted indoles and indolines starting from acyclic alpha-phosphoryloxy enecarbamates.

    Haruhiko Fuwa;Makoto Sasaki

Frequent Co-Authors

Makoto Sasaki
Makoto Sasaki Tohoku University
Kazuo Tachibana
Kazuo Tachibana University of Tokyo
Takeshi Iwatsubo
Takeshi Iwatsubo University of Tokyo
Luis M. Botana
Luis M. Botana University of Santiago de Compostela
Taisuke Tomita
Taisuke Tomita University of Tokyo
Tohru Fukuyama
Tohru Fukuyama Nagoya University
Takeshi Yasumoto
Takeshi Yasumoto Tohoku University
Mercedes R. Vieytes
Mercedes R. Vieytes University of Santiago de Compostela
Masashi Tsuda
Masashi Tsuda Kōchi University
Jordi Molgó
Jordi Molgó Centre national de la recherche scientifique, CNRS

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