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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
14173
World Ranking
10766
National Ranking
155

Overview

Sam Okret is affiliated with the Karolinska Institute in Sweden. Their research spans multiple fields within biomedical science, with a focus on understanding mechanisms related to lymphoma and cancer biology. Their principal areas of study include medicine, immunology, and microbiology, supported by additional expertise in pathology and forensic medicine, reproductive medicine, molecular biology, and nutrition and dietetics.

Okret's scholarly work addresses critical topics such as lymphoma diagnosis and treatment, galectins and cancer biology, ovarian cancer diagnosis and treatment, retinoids in leukemia and cellular processes, vitamin C and antioxidants research, acute lymphoblastic leukemia research, and chronic lymphocytic leukemia research.

Their recent publications include the following papers:

  • Estrogen Receptor β (ESR2) Transcriptome and Chromatin Binding in a Mantle Cell Lymphoma Tumor Model Reveal the Tumor-Suppressing Mechanisms of Estrogens, 2022, Cancers
  • Sex- and Female Age-Dependent Differences in Gene Expression in Diffuse Large B-Cell Lymphoma-Possible Estrogen Effects, 2023, Cancers
  • A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis, 2023, Cell Reports

Frequent co-authors collaborating with Okret include:

  • Dan Huang
  • Mattias Berglund
  • Anastasios Damdimopoulos
  • Zhiqiang Huang
  • Rajitha Indukuri

Okret's work has been published primarily in the journals Cancers and Cell Reports. This publication pattern reflects their engagement with leading research venues relevant to oncology and cellular biology.

Best Publications

  • Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA

    Roger Miesfeld;Sandro Rusconi;Paul J. Godowski;Bonnie A. Maler

  • Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region.

    Farhang Payvar;Donald DeFranco;Gary L. Firestone;Bruce Edgar

  • Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor.

    Kjell Fuxe;Ann-Charlotte Wikström;Sam Okret;Luigi F. Agnati

  • Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.

    E. Caldenhoven;J. Liden;S. Wissink;A. Van de Stolpe

  • Glucocorticoid receptor immunoreactivity in monoaminergic neurons of rat brain

    A Härfstrand;K Fuxe;A Cintra;L F Agnati

  • Biochemistry molecular biology, and physiology of the glucocorticoid receptor

    Jan-Ake Gustafsson;J. Carlstedt-Duke;L. Poellinger;S. Okret

  • Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids.

    Franck Delaunay;Akhtar Khan;Antonio Cintra;Behrous Davani

  • Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms.

    Yu Dong;Lorenz Poellinger;Jan-Åke Gustafsson;Sam Okret

  • Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

    Farhang Payvar;Orjan Wrange;Jan Carlstedt-Duke;Sam Okret

  • Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells

    Roger Miesfeld;Sam Okret;Ann Charlotte Wikström;Örjan Wrange

  • Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone.

    Sam Okret;Lorenz Poellinger;Yu Dong;Jan-Ake Gustafsson

  • Localization of glucocorticoid receptor mRNA in the male rat brain by in situ hybridization

    Marie Aronsson;Kjell Fuxe;Yu Dong;Luigi F. Agnati

  • Monoclonal antibodies against the rat liver glucocorticoid receptor.

    Sam Okret;Ann-Charlotte Wikstrom;Orjan Wrange;Birger Andersson

  • Mapping and computer assisted morphometry and microdensitometry of glucocorticoid receptor immunoreactive neurons and glial cells in the rat central nervous system

    A Cintra;Michele Zoli;L Rosen;Luigi Francesco Agnati

  • Intracellular Localization of the Glucocorticoid Receptor: Evidence for Cytoplasmic and Nuclear Localization*

    Ann-Charlotte Wikström;Oddmund Bakke;Sam Okret;Mikael Brönnegård

  • The glucocorticoid receptor recognizes a specific nucleotide sequence in hepatitis B virus DNA causing increased activity of the HBV enhancer.

    Ran Tur-Kaspa;Yosef Shaul;David D. Moore;Robert D. Burk

  • Characterization of the purified activated glucocorticoid receptor from rat liver cytosol.

    O Wrange;S Okret;M Radojćić;J Carlstedt-Duke

  • Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.

    Jan Carlstedt-Duke;Sam Okret;Orjan Wrange;Jan-Ake Gustafsson

  • A New Function for the C-terminal Zinc Finger of the Glucocorticoid Receptor REPRESSION OF RelA TRANSACTIVATION

    Johan Liden;Franck Delaunay;Ingalill Rafter;Jan-Ã…ke Gustafsson

  • p57(Kip2) cooperates with Nurr1 in developing dopamine cells.

    Bertrand Joseph;Åsa Wallén-Mackenzie;Gérard Benoit;Takashi Murata

Frequent Co-Authors

Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
Mikael Jondal
Mikael Jondal Karolinska Institute
Kjell Fuxe
Kjell Fuxe Karolinska Institute
Jan Carlstedt-Duke
Jan Carlstedt-Duke Nanyang Technological University
Antonio Cintra
Antonio Cintra Karolinska Institute
Anders Härfstrand
Anders Härfstrand Karolinska Institute
Lorenz Poellinger
Lorenz Poellinger Karolinska Institute
Luigi F. Agnati
Luigi F. Agnati University of Modena and Reggio Emilia
David J. McConkey
David J. McConkey Johns Hopkins University
Menek Goldstein
Menek Goldstein New York University

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