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D-Index & Metrics

Molecular Biology

D-Index
64
Citations
26100
World Ranking
1701
National Ranking
39

Overview

Tian Xu is affiliated with Westlake University in China and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily focuses on molecular biology with notable applications in oncology, surgery, pulmonary and respiratory medicine, and epidemiology.

The scientist's work encompasses a range of topics including pluripotent stem cells research, CRISPR and genetic engineering, autophagy in disease and therapy, epigenetics and DNA methylation, reproductive biology and fertility, tissue engineering and regenerative medicine, and radiomics and machine learning in medical imaging.

Among Tian Xu's recent publications are:

  • Development and validation of a radiomics-based nomogram for predicting a major pathological response to neoadjuvant immunochemotherapy for patients with potentially resectable non-small cell lung cancer, 2023, Frontiers in Immunology
  • Selective autophagic degradation of ACLY (ATP citrate lyase) maintains citrate homeostasis and promotes oocyte maturation, 2022, Autophagy
  • TDG is a pig-specific epigenetic regulator with insensitivity to H3K9 and H3K27 demethylation in nuclear transfer embryos, 2021, Stem Cell Reports
  • ATG7-mediated autophagy facilitates embryonic stem cell exit from naive pluripotency and marks commitment to differentiation, 2022, Autophagy
  • Genomic Profiling Reveals the Variant Landscape of Sporadic Parathyroid Adenomas in Chinese Population, 2023, The Journal of Clinical Endocrinology & Metabolism

Tian Xu frequently publishes in the following venues:

  • Autophagy
  • Cell Death and Disease
  • International Journal of Molecular Sciences
  • Frontiers in Immunology
  • Stem Cell Reports

Frequent collaborators in Tian Xu's research include:

  • Yi-Liang Miao
  • Jilong Zhou
  • Chengli Dou
  • Hainan He
  • Xin Liu

The breadth of Tian Xu's work shows extensive involvement in interdisciplinary scientific studies integrating aspects of molecular biology, regenerative medicine, and advanced biomedical techniques. Their contributions include studies on stem cell pluripotency, gene editing technologies, and disease-related autophagy mechanisms, reflecting ongoing engagement with cutting-edge biomedical research topics.

Best Publications

  • Analysis of genetic mosaics in developing and adult Drosophila tissues

    Tian Xu;Gerald M. Rubin

  • Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

    Ken Inoki;Yong Li;Tian Xu;Kun Liang Guan

  • Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

    Kristi A. Wharton;Kristen M. Johansen;Tian Xu;Spyros Artavanis-Tsakonas

  • Akt regulates growth by directly phosphorylating Tsc2.

    Christopher J. Potter;Laura G. Pedraza;Tian Xu

  • Efficient Transposition of the piggyBac (PB) Transposon in Mammalian Cells and Mice

    Sheng Ding;Xiaohui Wu;Gang Li;Min Han;Min Han

  • Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

    Richard G. Fehon;Pamela J. Kooh;Ilaria Rebay;Cathy L. Regan

  • Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase

    Tian Xu;Waiyi Wang;Sheng Zhang;R. A. Stewart

  • A genetic screen in drosophila for metastatic behavior

    Tian Xu;Raymond Pagliarini;Tatsushi Igaki

  • Drosophila Tsc1 Functions with Tsc2 to Antagonize Insulin Signaling in Regulating Cell Growth, Cell Proliferation, and Organ Size

    Christopher J. Potter;He Huang;Tian Xu

  • Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction

    Maie A R St John;Wufan Tao;Xiaolan Fei;Royd Fukumoto

  • Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian

    Huilin Qi;Matthew D. Rand;Xiaohui Wu;Nenad Sestan

  • SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

    Xiaochang Zhang;Kai Lei;Xiaobing Yuan;Xiaohui Wu

  • Loss of Cell Polarity Drives Tumor Growth and Invasion through JNK Activation in Drosophila

    Tatsushi Igaki;Raymond A. Pagliarini;Tian Xu

  • SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice.

    Xu Ding;Rener Xu;Juehua Yu;Tian Xu;Tian Xu

  • Interaction between Ras V12 and scribbled clones induces tumour growth and invasion

    Ming Wu;José Carlos Pastor-Pareja;Tian Xu;Tian Xu

  • KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis

    Jenny Rooke;Duojia Pan;Tian Xu;Gerald M. Rubin

  • PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development.

    He Huang;Christopher J. Potter;Wufan Tao;Da Ming Li

  • Shaping cells and organs in Drosophila by opposing roles of fat body-secreted Collagen IV and perlecan.

    José Carlos Pastor-Pareja;Tian Xu;Tian Xu

  • Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity

    Wufan Tao;Sheng Zhang;Gregory S. Turenchalk;Rodney A. Stewart

  • An innate immune response of blood cells to tumors and tissue damage in Drosophila

    José Carlos Pastor-Pareja;Ming Wu;Tian Xu

Frequent Co-Authors

Yuan Zhuang
Yuan Zhuang Duke University
Min Han
Min Han University of Colorado Boulder
Gabriel G. Haddad
Gabriel G. Haddad University of California, San Diego
Spyros Artavanis-Tsakonas
Spyros Artavanis-Tsakonas Harvard University
Kun-Liang Guan
Kun-Liang Guan Westlake University
Peter M. Glazer
Peter M. Glazer Yale University
Richard G. Fehon
Richard G. Fehon University of Chicago
Nenad Sestan
Nenad Sestan Yale University
Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute
Richard P. Lifton
Richard P. Lifton Rockefeller University

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