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D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
15460
World Ranking
19195
National Ranking
7837

Overview

Richard G. Fehon is affiliated with the University of Chicago in the United States. Their research primarily focuses on areas within Biochemistry, Genetics, and Molecular Biology, with a considerable number of publications spanning cell biology, molecular biology, cellular and molecular neuroscience, biophysics, and organic chemistry.

The scientist's recent work encompasses several papers published between 2020 and 2024, covering topics related to developmental biology, cellular mechanics, and signaling pathways. Selected publications include:

  • "Rho1 activation recapitulates early gastrulation events in the ventral, but not dorsal, epithelium of Drosophila embryos" (2020, eLife)
  • "Apical polarity and actomyosin dynamics control Kibra subcellular localization and function in Drosophila Hippo signaling" (2023, Developmental Cell)
  • "Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription" (2021, eLife)
  • "Cortical tension promotes Kibra degradation via Par-1" (2023, Molecular Biology of the Cell)
  • "Dachsous and Fat coordinately repress the Dachs-Dlish-Approximated complex to control growth" (2024, The Journal of Cell Biology)

Frequent collaborators include Sherzod A. Tokamov, Michael Glotzer, Anne Ullyot, Ashley Rich, and Nicki Nouri. These collaborations have often resulted in multiple co-authored publications addressing overlapping fields of cell biology and molecular signaling.

Richard G. Fehon's work has appeared repeatedly in publication venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Molecular Biology of the Cell, Developmental Cell, and The Journal of Cell Biology.

Research topics pursued by this scientist incorporate:

  • Hippo pathway signaling and YAP/TAZ
  • Wnt/β-catenin signaling in development and cancer
  • Cellular mechanics and interactions
  • Developmental biology and gene regulation
  • Neurobiology and insect physiology research
  • Advanced fluorescence microscopy techniques
  • Click chemistry and applications

The combination of these topics with their main fields and subfields of study situates their contributions at the intersection of cellular behavior, molecular pathways, and developmental processes, particularly within model organisms such as Drosophila.

Best Publications

  • ERM proteins and merlin: integrators at the cell cortex

    Anthony Bretscher;Kevin Edwards;Richard G. Fehon

  • Organizing the cell cortex: the role of ERM proteins

    Richard G. Fehon;Andrea I. McClatchey;Anthony Bretscher

  • Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

    Ilaria Rebay;Robert J. Fleming;Richard G. Fehon;Lucy Cherbas

  • Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

    Richard G. Fehon;Pamela J. Kooh;Ilaria Rebay;Cathy L. Regan

  • Protein interaction mapping: A Drosophila case study

    Etienne Formstecher;Sandra Aresta;Vincent Collura;Alexandre Hamburger

  • The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane

    Athar H. Chishti;Anthony C. Kim;Shirin M. Marfatia;Mohini Lutchman

  • Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor.

    Ilaria Rebay;Richard G. Fehon;Spyros Artavanis-Tsakonas

  • Epithelial Cell Polarity and Cell Junctions in Drosophila

    Ulrich Tepass;Guy Tanentzapf;Robert E. Ward;Richard G. Fehon

  • Delineation of a Fat tumor suppressor pathway

    Eunjoo Cho;Yongqiang Feng;Cordelia Rauskolb;Sushmita Maitra

  • A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene

    Richard G. Fehon;Iain A. Dawson;Spyridon Artavanis-Tsakonas

  • Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function.

    R G Fehon;K Johansen;I Rebay;S Artavanis-Tsakonas

  • Ezrin, Radixin and Moesin: key regulators of membrane-cortex interactions and signaling.

    Amanda L Neisch;Richard G Fehon

  • Neuroglian, Gliotactin, and the Na+/K+ ATPase are essential for septate junction function in Drosophila.

    Jennifer L. Genova;Richard G. Fehon

  • Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development

    P. J. Kooh;R. G. Fehon;M. A. T. Muskavitch

  • Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity

    Olga Speck;Sarah C. Hughes;Sarah C. Hughes;Nicole K. Noren;Rima M. Kulikauskas;Rima M. Kulikauskas

  • Tao-1 Phosphorylates Hippo/MST Kinases to Regulate the Hippo-Salvador-Warts Tumor Suppressor Pathway

    Julian C. Boggiano;Pamela J. Vanderzalm;Richard G. Fehon

  • The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling.

    Sushmita Maitra;Rima M. Kulikauskas;Heather Gavilan;Richard G. Fehon

  • Drosophila coracle, a member of the protein 4.1 superfamily, has essential structural functions in the septate junctions and developmental functions in embryonic and adult epithelial cells.

    Rebecca S. Lamb;Robert E. Ward;Liang Schweizer;Richard G. Fehon

  • Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex

    Andrea I. McClatchey;Richard G. Fehon

  • The involvement of the Notch locus in Drosophila oogenesis.

    Tian Xu;L. A. Caron;R. G. Fehon;S. Artavanis-Tsakonas

Frequent Co-Authors

Marc A. T. Muskavitch
Marc A. T. Muskavitch Biogen (United States)
Spyros Artavanis-Tsakonas
Spyros Artavanis-Tsakonas Harvard University
Anthony Bretscher
Anthony Bretscher Cornell University
Andrea I. McClatchey
Andrea I. McClatchey Harvard University
Bruno Goud
Bruno Goud Institute Curie
Pierre Legrain
Pierre Legrain Institut Pasteur
Ludger Johannes
Ludger Johannes Institute Curie
Olivier Delattre
Olivier Delattre PSL University

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