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Robert S. Haltiwanger

Robert S. Haltiwanger

D-Index & Metrics

Chemistry

D-Index
70
Citations
14730
World Ranking
5991
National Ranking
1827

Biology and Biochemistry

D-Index
74
Citations
16438
World Ranking
5724
National Ranking
2708

Overview

Robert S. Haltiwanger is affiliated with the University of Georgia in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a notable focus on Molecular Biology and Immunology among subfields. The scientist's body of work covers various topics including Glycosylation and Glycoproteins Research, Developmental Biology and Gene Regulation, and Galectins and Cancer Biology, alongside Carbohydrate Chemistry and Synthesis, Connective Tissue Disorders Research, Protease and Inhibitor Mechanisms, and Lysosomal Storage Disorders Research.

Throughout their career, Robert S. Haltiwanger has contributed numerous publications, frequently appearing in journals such as the Journal of Biological Chemistry, The FASEB Journal, Glycobiology, bioRxiv (Cold Spring Harbor Laboratory), and Molecules.

Co-authorship has been an important aspect of their research, collaborating multiple times with the following researchers:

  • Atsuko Ito
  • Huilin Hao
  • Kenjiroo Matsumoto
  • Kelvin B. Luther
  • Megumi Takeuchi

Some recent papers authored by or involving Robert S. Haltiwanger include:

  • "Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2," published in 2020 in the Journal of Biological Chemistry
  • "Fucosylation of HLA-DRB1 regulates CD4+ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy," published in 2023 in Nature Cancer
  • "Fringe GlcNAc-transferases differentially extend O-fucose on endogenous NOTCH1 in mouse activated T cells," published in 2022 in the Journal of Biological Chemistry
  • "Diseases related to Notch glycosylation," published in 2020 in Molecular Aspects of Medicine
  • "POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, α-dystroglycan hypoglycosylation and a distinctive radiological pattern," published in 2020 in Acta Neuropathologica

Best Publications

  • Fringe is a glycosyltransferase that modifies Notch

    Daniel J. Moloney;Vladislav M. Panin;Stuart H. Johnston;Stuart H. Johnston;Jihua Chen

  • Role of Glycosylation in Development

    Robert S Haltiwanger;John B Lowe

  • Glycosylation of nuclear and cytoplasmic proteins. Purification and characterization of a uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase.

    Robert S. Haltiwanger;Mellissa A. Blomberg;Gerald Warren Hart

  • Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.

    G. D. Holt;C. M. Snow;A. Senior;R. S. Haltiwanger

  • Glycosylation in the nucleus and cytoplasm

    Gerald W. Hart;Robert S. Haltiwanger;Gordon D. Holt;William G. Kelly

  • Enzymatic addition of O-GlcNAc to nuclear and cytoplasmic proteins. Identification of a uridine diphospho-N-acetylglucosamine:peptide beta-N-acetylglucosaminyltransferase.

    Robert S. Haltiwanger;Gordon D. Holt;Gerald Warren Hart

  • Biological functions of fucose in mammals.

    Michael Schneider;Esam Al-Shareffi;Esam Al-Shareffi;Robert S Haltiwanger;Robert S Haltiwanger

  • Mammalian Notch1 Is Modified with Two Unusual Forms ofO-Linked Glycosylation Found on Epidermal Growth Factor-like Modules

    Daniel J. Moloney;Louisa H. Shair;Frederick M. Lu;Jie Xia

  • Modulation of O-LinkedN-Acetylglucosamine Levels on Nuclear and Cytoplasmic Proteins in Vivo Using the PeptideO-GlcNAc-β-N-acetylglucosaminidase InhibitorO-(2-Acetamido-2-deoxy-dglucopyranosylidene)amino-N-phenylcarbamate

    Robert S. Haltiwanger;Kathleen Grove;Glenn A. Philipsberg

  • Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling

    Melih Acar;Hamed Jafar-Nejad;Hideyuki Takeuchi;Akhila Rajan

  • Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase.

    Yang Wang;Li Shao;Shaolin Shi;Reed J. Harris

  • Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.

    Vincent C. Luca;Vincent C. Luca;Byoung Choul Kim;Byoung Choul Kim;Chenghao Ge;Shinako Kakuda

  • Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains.

    Hiroyuki O. Ishikawa;Hideyuki Takeuchi;Robert S. Haltiwanger;Kenneth D. Irvine

  • Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.

    Y-Ting. Yan;J-Jan. Liu;Y. Luo

  • Glycosylation of nuclear and cytoplasmic proteins is ubiquitous and dynamic

    Robert S. Haltiwanger;William G. Kelly;Elizabeth P. Roquemore;Melissa A. Blomberg

  • Fringe Modifies O-Fucose on Mouse Notch1 at Epidermal Growth Factor-like Repeats within the Ligand-binding Site and the Abruptex Region

    Li Shao;Daniel J. Moloney;Robert S. Haltiwanger

  • Notch Ligands Are Substrates for Protein O-Fucosyltransferase-1 and Fringe*

    Vladislav M. Panin;Li Shao;Liang Lei;Daniel J. Moloney

  • Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi

    Rodrigo Fernandez-Valdivia;Hideyuki Takeuchi;Amin Samarghandi;Mario Lopez

  • Erythrocytes contain cytoplasmic glycoproteins. O-linked GlcNAc on Band 4.1.

    G. D. Holt;R. S. Haltiwanger;C. R. Torres;Gerald Warren Hart

  • Emerging structural insights into glycosyltransferase-mediated synthesis of glycans

    Kelley W. Moremen;Robert S. Haltiwanger

  • Significance of glycosylation in Notch signaling.

    Hideyuki Takeuchi;Robert S. Haltiwanger

Frequent Co-Authors

Gerald W. Hart
Gerald W. Hart University of Georgia
Suneel S. Apte
Suneel S. Apte Case Western Reserve University
Pamela Stanley
Pamela Stanley Albert Einstein College of Medicine
Hudson H. Freeze
Hudson H. Freeze Discovery Institute
K. Christopher Garcia
K. Christopher Garcia Stanford University
Huilin Li
Huilin Li Van Andel Institute
Kenneth D. Irvine
Kenneth D. Irvine Rutgers, The State University of New Jersey
Rita Gerardy-Schahn
Rita Gerardy-Schahn Hannover Medical School
Howard R. Morris
Howard R. Morris Imperial College London

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