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David J. Vocadlo

David J. Vocadlo

Simon Fraser University
Canada

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
27230
World Ranking
6514
National Ranking
234

David J. Vocadlo publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where David J. Vocadlo sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 264 publications — 71st percentile

71% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

David J. Vocadlo D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David J. Vocadlo sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 71 D-Index — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

David J. Vocadlo is affiliated with Simon Fraser University in Canada and focuses on research in biochemistry, genetics, and molecular biology, with significant contributions across medicine and chemistry. Their work spans several key subfields such as molecular biology, organic chemistry, physiology, cell biology, and immunology.

The scientist's research primarily addresses topics including carbohydrate chemistry and synthesis, glycosylation and glycoproteins research, lysosomal storage disorders research, cellular transport and secretion, galectins and cancer biology, biochemical and molecular research, and monoclonal and polyclonal antibodies research.

Frequent collaboration partners include Matthew C. Deen, G.J. Davies, Sha Zhu, Yanping Zhu, and Matthew G. Alteen.

Publications by David J. Vocadlo have appeared notably in venues such as bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Angewandte Chemie International Edition, Angewandte Chemie, and the Journal of the American Chemical Society.

Recent papers demonstrate a focus on O-GlcNAcase inhibition and its biological effects as well as methodological advances in protein modification analysis. These include:

  • MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy, 2020, Journal of Pharmacology and Experimental Therapeutics
  • Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of α-synuclein preformed fibrils, 2020, FEBS Journal
  • Monitoring and modulating O-GlcNAcylation: assays and inhibitors of O-GlcNAc processing enzymes, 2021, Current Opinion in Structural Biology
  • Precision Mapping of O-Linked N-Acetylglucosamine Sites in Proteins Using Ultraviolet Photodissociation Mass Spectrometry, 2020, Journal of the American Chemical Society
  • Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome, 2022, Journal of the American Chemical Society

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo.

    Scott A Yuzwa;Matthew S Macauley;Julia E Heinonen;Xiaoyang Shan

  • Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

    David J. Vocadlo;Gideon J. Davies;Gideon J. Davies;Roger Laine;Stephen G. Withers

  • A chemical approach for identifying O-GlcNAc-modified proteins in cells

    David J. Vocadlo;Howard C. Hang;Eun Ju Kim;John A. Hanover

  • Increasing O -GlcNAc slows neurodegeneration and stabilizes tau against aggregation

    Scott A Yuzwa;Xiaoyang Shan;Matthew S Macauley;Matthew S Macauley;Thomas Clark

  • Mechanistic insights into glycosidase chemistry.

    David J Vocadlo;Gideon J Davies

  • O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

    Matthew S. Macauley;Garrett E. Whitworth;Aleksandra W. Debowski;Danielle Chin

  • O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway.

    Christina M. Ferrer;Thomas P. Lynch;Valerie L. Sodi;John N. Falcone

  • Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase.

    Brian L. Mark;David J. Vocadlo;Spencer Knapp;Barbara L. Triggs-Raine

  • NAG-thiazoline, An N-Acetyl-β-hexosaminidase Inhibitor That Implicates Acetamido Participation

    Spencer Knapp;David Vocadlo;Zhinong Gao;Brian Kirk

  • Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

    Tracey M Gloster;Wesley F Zandberg;Julia E Heinonen;David L Shen

  • The emerging link between O-GlcNAc and Alzheimer disease.

    Yanping Zhu;Xiaoyang Shan;Scott A. Yuzwa;David J. Vocadlo

  • Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells

    Zhiyuan Ma;David J. Vocadlo;Keith Vosseller

  • O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond

    Scott A. Yuzwa;David J. Vocadlo

  • Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc)

    Donald A. R. Sinclair;Monika Syrzycka;Matthew S. Macauley;Tara Rastgardani

  • Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity

    Rebecca J Dennis;Edward J Taylor;Matthew S Macauley;Keith A Stubbs

  • Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology

    Tracey M Gloster;David J Vocadlo

  • HCF-1 is cleaved in the active site of O-GlcNAc transferase.

    Michael B. Lazarus;Jiaoyang Jiang;Vaibhav Kapuria;Tanja Bhuiyan

  • Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise

    Garrett E. Whitworth;Matthew S. Macauley;Keith A. Stubbs;Rebecca J. Dennis

  • O-GlcNAc processing enzymes: catalytic mechanisms, substrate specificity, and enzyme regulation.

    David J Vocadlo

Frequent Co-Authors

Gideon J. Davies
Gideon J. Davies University of York
Stephen G. Withers
Stephen G. Withers University of British Columbia
Alisdair B. Boraston
Alisdair B. Boraston University of Victoria
Harold G. Selnick
Harold G. Selnick MSD (United States)
Robert D. Burke
Robert D. Burke University of Victoria
Mirjam Czjzek
Mirjam Czjzek Sorbonne University
Michael N. G. James
Michael N. G. James University of Alberta
Antonio Oliver
Antonio Oliver Instituto de Salud Carlos III
Spencer Knapp
Spencer Knapp Rutgers, The State University of New Jersey
James C. Paton
James C. Paton University of Adelaide

External Links

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Related Online Degrees & Career Pathways

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For those interested in pharmaceuticals, online pharmd programs provide training for pharmacy licensure and advanced practice roles. If your passion lies in human performance and fitness, you might consider a program like an online exercise physiology degree that combines science with hands-on skill development.

Additionally, kinesiology online programs offer a science-based curriculum focused on movement, rehabilitation, and sports. For those looking to address rising mental health needs, the pmhnp online programs are a fast track to becoming a certified Psychiatric-Mental Health Nurse Practitioner.

These online pathways complement traditional biology and biochemistry, expanding career options in healthcare, research, wellness, and beyond.

Best Scientists Citing David J. Vocadlo

Stephen G. Withers

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University of British Columbia

Publications: 85

Gideon J. Davies

Gideon J. Davies

University of York

Publications: 83

Carolyn R. Bertozzi

Carolyn R. Bertozzi

Stanford University

Publications: 69

Gerald W. Hart

Gerald W. Hart

University of Georgia

Publications: 67

Daan M. F. van Aalten

Daan M. F. van Aalten

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Publications: 56

Carme Rovira

Carme Rovira

University of Barcelona

Publications: 52

John A. Hanover

John A. Hanover

National Institutes of Health

Publications: 42

Alisdair B. Boraston

Alisdair B. Boraston

University of Victoria

Publications: 35

Chi-Huey Wong

Chi-Huey Wong

Scripps Research Institute

Publications: 32

Bernard Henrissat

Bernard Henrissat

Technical University of Denmark

Publications: 30

Spencer J. Williams

Spencer J. Williams

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Publications: 29

Harry Brumer

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Publications: 26

Peng George Wang

Peng George Wang

Georgia State University

Publications: 25

Johannes M. F. G. Aerts

Johannes M. F. G. Aerts

Leiden University

Publications: 23

Herman S. Overkleeft

Herman S. Overkleeft

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Publications: 23

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Shahriar Mobashery

University of Notre Dame

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