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Spencer J. Williams

Spencer J. Williams

D-Index & Metrics

Chemistry

D-Index
44
Citations
7817
World Ranking
16770
National Ranking
371

Overview

Spencer J. Williams is affiliated with the University of Melbourne in Australia and has contributed extensively to research primarily within the field of Biochemistry, Genetics and Molecular Biology. Their body of work includes over 55 publications in this domain, with significant focus on several subfields such as Molecular Biology, Environmental Chemistry, Organic Chemistry, Materials Chemistry, and Immunology.

The main topics covered in their research encompass Environmental Chemistry and Analysis, Carbohydrate Chemistry and Synthesis, Enzyme Production and Characterization, Water Treatment and Disinfection, Microbial Community Ecology and Physiology, Glycosylation and Glycoproteins Research, and Biofuel production and bioconversion.

Among the recent papers authored or coauthored by Williams are:

  • "α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19" (2020, Biochemical Society Transactions)
  • "Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors" (2020, The Journal of Experimental Medicine)
  • "An Epoxide Intermediate in Glycosidase Catalysis" (2020, ACS Central Science)
  • "Sulfoglycolysis: catabolic pathways for metabolism of sulfoquinovose" (2021, Chemical Society Reviews)
  • "A Sulfoglycolytic Entner-Doudoroff Pathway in Rhizobium leguminosarum bv. trifolii SRDI565" (2020, Applied and Environmental Microbiology)

Williams frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Cambridge Structural Database, Chemical Science, Proceedings of the National Academy of Sciences, and the Journal of Biological Chemistry.

The scientist has collaborated frequently with other researchers, including G.J. Davies, Ethan D. Goddard-Borger, Laura Burchill, Mahima Sharma, and Nichollas E. Scott, reflecting integrated work across related biochemical and molecular biology fields.

Best Publications

  • Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

    Fiona Cuskin;Fiona Cuskin;Elisabeth C. Lowe;Max J. Temple;Yanping Zhu;Yanping Zhu

  • Glycosyl fluorides in enzymatic reactions.

    Spencer J. Williams;Stephen G. Withers

  • Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes

    Wade Abbott;Orly Alber;Ed Bayer;Jean-Guy Berrin

  • 'Click' cycloaddition catalysts: copper(I) and copper(II) tris(triazolylmethyl)amine complexes.

    Paul S Donnelly;Shannon D Zanatta;Steven C Zammit;Jonathan M White

  • Dissecting conformational contributions to glycosidase catalysis and inhibition

    Gaetono Speciale;Andrew James Thompson;Gideon John Davies;Spencer J Williams

  • A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.

    Alan Cartmell;Jose Muñoz-Muñoz;Jose Muñoz-Muñoz;Jonathon A. Briggs;Didier A. Ndeh

  • Mechanistic insights into a Ca2+-dependent family of α-mannosidases in a human gut symbiont

    Yanping Zhu;Michael D L Suits;Andrew J Thompson;Sambhaji Chavan

  • Sulfotransferases and Sulfatases in Mycobacteria

    Joseph D Mougous;Richard E Green;Spencer J Williams;Steven E Brenner

  • High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans xylanase 10A with bound substrates reveal a novel mode of xylan binding.

    Valerie Notenboom;Alisdair B. Boraston;Spencer J. Williams;Douglas G. Kilburn

  • Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.

    Spencer J. Williams;Brian L. Mark;David J. Vocadlo;Michael N.G. James

  • Trehalose is required for growth of Mycobacterium smegmatis.

    Peter J. Woodruff;Brian L. Carlson;Bunpote Siridechadilok;Matthew R. Pratt

  • A semi-invariant V[alpha]10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties

    Adam P Uldrich;Onisha Patel;Garth Cameron;Daniel G Pellicci

  • Protein--carbohydrate interactions: learning lessons from nature.

    Spencer J. Williams;Gideon J. Davies

  • Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity.

    Cheng Xue Qin;Xingqiang Chen;Richard A Hughes;Spencer J Williams

  • Conjugation of Transferrin to Azide-Modified CdSe/ZnS Core-Shell Quantum Dots using Cyclooctyne Click Chemistry

    Christine Schieber;Alessandra Bestetti;Jet Phey Lim;Anneke D. Ryan

  • Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination

    Pavla Bojarová;Spencer J Williams

  • Compartmentalization of Lipid Biosynthesis in Mycobacteria

    Yasu S. Morita;René Velasquez;Ellen Taig;Ross F. Waller

  • 5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria.

    Spencer J. Williams;Ryan H. Senaratne;Joseph D. Mougous;Lee W. Riley

  • Active-site Peptide “Fingerprinting” of Glycosidases in Complex Mixtures by Mass Spectrometry DISCOVERY OF A NOVEL RETAINING β-1,4-GLYCANASE IN CELLULOMONAS FIMI

    Omid Hekmat;Young-Wan Kim;Spencer J. Williams;Shouming He

  • Sulfoquinovose in the biosphere: occurrence, metabolism and functions.

    Ethan D. Goddard-Borger;Ethan D. Goddard-Borger;Spencer J. Williams

  • Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase

    Andrew J. Thompson;Rohan J. Williams;Zalihe Hakki;Dominic S. Alonzi

  • YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids

    Gaetano Speciale;Yi Jin;Gideon J Davies;Spencer J Williams

Frequent Co-Authors

Gideon J. Davies
Gideon J. Davies University of York
Carme Rovira
Carme Rovira University of Barcelona
Harry J. Gilbert
Harry J. Gilbert Newcastle University
Malcolm J. McConville
Malcolm J. McConville University of Melbourne
Jamie Rossjohn
Jamie Rossjohn Monash University
Jonathan M. White
Jonathan M. White University of Melbourne
Stephen G. Withers
Stephen G. Withers University of British Columbia
Paul S. Donnelly
Paul S. Donnelly University of Melbourne
Dale I. Godfrey
Dale I. Godfrey University of Melbourne
Darren J. Kelly
Darren J. Kelly Ascension Health

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