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Biology and Biochemistry

D-Index
52
Citations
11226
World Ranking
16586
National Ranking
6864

Overview

Thomas R. Moench is affiliated with Johns Hopkins University in the United States. Their research primarily focuses on Medicine, with substantial contributions to Immunology and Microbiology. The main subfields addressed include Immunology, Microbiology, Epidemiology, Infectious Diseases, and Biotechnology.

The scientist's work covers topics such as:

  • Reproductive tract infections research
  • Reproductive System and Pregnancy
  • Transgenic Plants and Applications
  • Monoclonal and Polyclonal Antibodies Research
  • Complement system in diseases
  • Blood groups and transfusion
  • Adolescent Sexual and Reproductive Health

Thomas R. Moench has published recent papers including:

  • The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis (2020) in PLoS Pathogens
  • Safety, acceptability, and pharmacokinetics of a monoclonal antibody-based vaginal multipurpose prevention film (MB66): A Phase I randomized trial (2021) in PLoS Medicine
  • Engineering monoclonal antibody-based contraception and multipurpose prevention technologies (2020) in Biology of Reproduction
  • Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women (2021) in EBioMedicine
  • ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study (2023) in American Journal of Obstetrics and Gynecology

Frequent coauthors working with Thomas R. Moench include:

  • Samuel K. Lai
  • Kevin J. Whaley (8 publications)
  • Alison Schaefer (8 publications)
  • Miles B. Brennan (7 publications)
  • Joseph A. Politch (6 publications)

Most of the scientist's work has appeared in venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • EBioMedicine
  • American Journal of Obstetrics and Gynecology
  • PLoS Pathogens

Best Publications

  • In vitro and in vivo: the story of nonoxynol 9.

    Sharon L Hillier;Thomas Moench;Robin Shattock;Roberta Black

  • Diffusion of macromolecules and virus-like particles in human cervical mucus.

    Stuart S. Olmsted;Janet L. Padgett;Ashley I. Yudin;Kevin J. Whaley

  • Origins of vaginal acidity: high d/l lactate ratio is consistent with bacteria being the primary source

    E.R. Boskey;R.A. Cone;K.J. Whaley;T.R. Moench

  • Vaginal pH and microbicidal lactic acid when lactobacilli dominate the microbiota.

    Deirdre E. O’Hanlon;Thomas R. Moench;Richard A. Cone

  • Acid production by vaginal flora in vitro is consistent with the rate and extent of vaginal acidification.

    E. R. Boskey;K. M. Telsch;K. J. Whaley;T. R. Moench

  • In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide

    Deirdre E O'Hanlon;Thomas R Moench;Richard A Cone

  • A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpes.

    Larry Zeitlin;Stuart S. Olmsted;Thomas R. Moench;Man Sung Co

  • Spatial segregation of mRNA encoding myelin-specific proteins

    B D Trapp;T Moench;M Pulley;E Barbosa

  • Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women

    Salim Safurdeen. Abdool Karim;Barbra Ann. Richardson;Gita. Ramjee;Irving F. Hoffman

  • Vaginal concentrations of lactic acid potently inactivate HIV

    Muriel Constanza Aldunate;David Tyssen;Adam Johnson;Tasnim Saifudin Zakir

  • Preventing disease by protecting the cervix: the unexplored promise of internal vaginal barrier devices.

    Thomas R. Moench;Tsungai Chipato;Nancy S. Padian

  • Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission

    Richard A Cone;Timothy Hoen;XiXi Wong;Raed Abusuwwa

  • SPL7013 Gel (VivaGel®) Retains Potent HIV-1 and HSV-2 Inhibitory Activity following Vaginal Administration in Humans

    Clare F Price;David Tyssen;Secondo Sonza;Secondo Sonza;Ashley Davie

  • Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent

    Kristen V. Khanna;Kevin J. Whaley;Larry Zeitlin;Thomas R. Moench

  • Basis of neurovirulence in Sindbis virus encephalomyelitis of mice.

    A. C. Jackson;T. R. Moench;B. D. Trapp;D. E. Griffin

  • Efficiency of in situ hybridization as a function of probe size and fixation technique.

    Thomas R. Moench;Howard Eliot Gendelman;Janice E. Clements;Opendra Narayan

  • Tests of vaginal microbicides in the mouse genital herpes model.

    Larry Zeitlin;Kevin J. Whaley;Tracy A. Hegarty;Thomas R. Moench

  • Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli

    Deirdre E O'Hanlon;Blair R Lanier;Thomas R Moench;Richard A Cone

  • Immunocytochemical identification and quantitation of the mononuclear cells in the cerebrospinal fluid, meninges, and brain during acute viral meningoencephalitis.

    Thomas R. Moench;Diane E. Griffin

  • Identification of the inflammatory cells in the central nervous system of patients with adrenoleukodystrophy

    Diane E. Griffin;Diane E. Griffin;Hugo W. Moser;Querubin Mendoza;Thomas R. Moench

Frequent Co-Authors

Diane E. Griffin
Diane E. Griffin Johns Hopkins University
Gilda Tachedjian
Gilda Tachedjian Burnet Institute
Deborah J. Anderson
Deborah J. Anderson Boston University
Kenneth H. Mayer
Kenneth H. Mayer Harvard Medical School
Richard T. Johnson
Richard T. Johnson Johns Hopkins University School of Medicine
Susan Cu-Uvin
Susan Cu-Uvin Brown University
Howard E. Gendelman
Howard E. Gendelman University of Nebraska Medical Center
Sharon L. Hillier
Sharon L. Hillier University of Pittsburgh
Barbra A. Richardson
Barbra A. Richardson University of Washington
Justin Hanes
Justin Hanes Johns Hopkins University

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