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Chemistry

D-Index
47
Citations
9486
World Ranking
15538
National Ranking
858

Overview

Stefan Howorka is affiliated with University College London in the United Kingdom, where they contribute to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Engineering. Their work spans across subfields such as Molecular Biology, Biomedical Engineering, Biomaterials, Water Science and Technology, and Computational Mechanics.

Their research topics focus heavily on advanced biosensing and bioanalysis techniques, nanopore and nanochannel transport studies, RNA interference and gene delivery, lipid membrane structure and behavior, supramolecular self-assembly in materials, membrane separation technologies, and ion-surface interactions and analysis.

Stefan Howorka has published numerous papers in notable scientific venues. Frequent publication venues include:

  • Nature Communications
  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • ACS Nano
  • Small

Their recent papers illustrate their focus on DNA nanopores and membrane technologies, with key publications including:

  • Highly shape- and size-tunable membrane nanopores made with DNA (2022) in Nature Nanotechnology
  • Nanopore DNA sequencing technologies and their applications towards single-molecule proteomics (2024) in Nature Chemistry
  • A reversibly gated protein-transporting membrane channel made of DNA (2022) in Nature Communications
  • Design, assembly, and characterization of membrane-spanning DNA nanopores (2020) in Nature Protocols
  • Creating complex protocells and prototissues using simple DNA building blocks (2023) in Nature Communications

The scientist collaborates frequently with the following coauthors:

  • Yongzheng Xing
  • Adam Dorey
  • Conor Lanphere
  • Jonathan R. Burns
  • Alexia Rottensteiner

These collaborations contribute to developments in nanopore technologies, molecular assemblies, and applications in proteomics and biosensing.

Best Publications

  • Nanopore analytics: sensing of single molecules

    Stefan Howorka;Zuzanna Siwy

  • Sequence-specific detection of individual DNA strands using engineered nanopores.

    Stefan Howorka;Stephen Cheley;Hagan Bayley;Hagan Bayley

  • Engineered voltage-responsive nanopores

    Zuzanna S. Siwy;Stefan Howorka

  • Detecting protein analytes that modulate transmembrane movement of a polymer chain within a single protein pore.

    Liviu Movileanu;Stefan Howorka;Orit Braha;Hagan Bayley;Hagan Bayley

  • A biomimetic DNA-based channel for the ligand-controlled transport of charged molecular cargo across a biological membrane

    Jonathan R. Burns;Astrid Seifert;Niels Fertig;Stefan Howorka

  • Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

    Parveen Goyal;Petya V. Krasteva;Nani Van Gerven;Francesca Gubellini

  • Self-Assembled DNA Nanopores That Span Lipid Bilayers

    Jonathan R. Burns;Eugen Stulz;Stefan Howorka

  • Kinetics of duplex formation for individual DNA strands within a single protein nanopore

    Stefan Howorka;Liviu Movileanu;Orit Braha;Hagan Bayley

  • Lipid‐Bilayer‐Spanning DNA Nanopores with a Bifunctional Porphyrin Anchor

    Jonathan R. Burns;Kerstin Göpfrich;James W. Wood;Vivek V. Thacker

  • SbsB structure and lattice reconstruction unveil Ca2+ triggered S-layer assembly.

    Ekaterina Baranova;Rémi Fronzes;Rémi Fronzes;Abel Garcia-Pino;Nani Van Gerven

  • DNA-Modified Polymer Pores Allow pH- and Voltage-Gated Control of Channel Flux

    Steven F. Buchsbaum;Gael Nguyen;Stefan Howorka;Zuzanna S. Siwy

  • Glass surfaces grafted with high-density poly(ethylene glycol) as substrates for DNA oligonucleotide microarrays.

    Robert Schlapak;Patrick Pammer;David Armitage;Rong Zhu

  • Protein components for nanodevices.

    Yann Astier;Hagan Bayley;Stefan Howorka

  • Stochastic Detection of Monovalent and Bivalent Protein–Ligand Interactions

    Stefan Howorka;Joonwoo Nam;Hagan Bayley;Hagan Bayley;Daniel Kahne

  • Spatial Presentation of Cholesterol Units on a DNA Cube as a Determinant of Membrane Protein-Mimicking Functions.

    Pongphak Chidchob;Daniel Offenbartl-Stiegert;Dillon McCarthy;Xin Luo

  • Probing Distance and Electrical Potential within a Protein Pore with Tethered DNA

    Stefan Howorka;Hagan Bayley;Hagan Bayley

  • Biosensor compositions and methods of use

    Hagan P. Bayley;Stefan G. Howorka;Liviu Movileanu

  • Membrane-spanning DNA nanopores with cytotoxic effect.

    Jonathan R. Burns;Noura Al-Juffali;Sam M. Janes;Stefan Howorka

  • Biomimetic Hybrid Nanocontainers with Selective Permeability.

    Lea Messager;Jonathan R. Burns;Jungyeon Kim;Denis Cecchin

  • Imaging surface charges of individual biomolecules.

    Carl Leung;Helen Kinns;Bart W. Hoogenboom;Stefan Howorka

  • A protein pore with a single polymer chain tethered within the lumen

    Stefan Howorka;Liviu Movileanu;Xiaofeng Lu;Melissa Magnon

Frequent Co-Authors

Hagan Bayley
Hagan Bayley University of Oxford
Zuzanna S. Siwy
Zuzanna S. Siwy University of California, Irvine
Peter Hinterdorfer
Peter Hinterdorfer Johannes Kepler University of Linz
Uwe B. Sleytr
Uwe B. Sleytr BOKU University
Werner Lubitz
Werner Lubitz BIRD-C GmbH
Hermann J. Gruber
Hermann J. Gruber Johannes Kepler University of Linz
Friedrich Schäffler
Friedrich Schäffler Johannes Kepler University of Linz
Ulrich F. Keyser
Ulrich F. Keyser University of Cambridge
Wojciech Chrzanowski
Wojciech Chrzanowski University of Sydney
Robert Tampé
Robert Tampé Goethe University Frankfurt

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