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Chemistry

D-Index
72
Citations
15332
World Ranking
5385
National Ranking
1669

Biology and Biochemistry

D-Index
74
Citations
16030
World Ranking
5732
National Ranking
2711

Overview

Kelley W. Moremen is affiliated with the University of Georgia in the United States and has a research focus primarily in biochemistry, genetics, and molecular biology. Their scholarly work spans multiple subfields including molecular biology, organic chemistry, immunology, plant science, and radiology, nuclear medicine, and imaging.

The scientist's research topics cover a range of specialized areas, notably:

  • Glycosylation and glycoproteins research
  • Carbohydrate chemistry and synthesis
  • Monoclonal and polyclonal antibodies research
  • Galectins and cancer biology
  • Proteoglycans and glycosaminoglycans research
  • Polysaccharides and plant cell walls
  • Enzyme production and characterization

Recent publications authored or co-authored by Moremen include:

  • Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases (2020, eLife)
  • Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses (2021, Nature Communications)
  • Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration (2022, Nature Communications)
  • Molecular Mechanism of Polysaccharide Acetylation by the Arabidopsis Xylan O-acetyltransferase XOAT1 (2020, The Plant Cell)
  • Variable posttranslational modifications of severe acute respiratory syndrome coronavirus 2 nucleocapsid protein (2021, Glycobiology)

Co-authorship collaborations commonly occur with:

  • Digantkumar Chapla
  • Jeong-Yeh Yang
  • Chin Huang
  • Geert-Jan Boons
  • Breeanna R. Urbanowicz

Moremen's work has been published extensively in frequent venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Glycobiology
  • Nature Communications
  • Angewandte Chemie

Best Publications

  • Vertebrate protein glycosylation: diversity, synthesis and function

    Kelley W. Moremen;Michael Tiemeyer;Alison V. Nairn

  • Glycosidases of the asparagine-linked oligosaccharide processing pathway

    Kelley Moremen;Robert B. Trimble;Annetté Herscovics

  • Expression system for structural and functional studies of human glycosylation enzymes.

    K.W. Moremen;A. Ramiah;M. Stuart;J. Steel

  • Regulation of glycan structures in animal tissues: transcript profiling of glycan-related genes.

    Alison V. Nairn;William S. York;Kyle Harris;Erica M. Hall

  • Alpha-Mannosidase-II Deficiency Results in Dyserythropoiesis and Unveils an Alternate Pathway in Oligosaccharide Biosynthesis

    Daniel Chui;Masayoshi Oh-Eda;Yung-Feng Liao;Krishnasamy Panneerselvam

  • Two Arabidopsis proteins synthesize acetylated xylan in vitro

    Breeanna R. Urbanowicz;Maria J. Peña;Heather A. Moniz;Kelley W. Moremen

  • Guanosine diphosphatase is required for protein and sphingolipid glycosylation in the Golgi lumen of Saccharomyces cerevisiae.

    Claudia Abeijon;Ken Yanagisawa;Elisabet C. Mandon;Alex Hausler

  • Identification, Expression, and Characterization of a cDNA Encoding Human Endoplasmic Reticulum Mannosidase I, the Enzyme That Catalyzes the First Mannose Trimming Step in Mammalian Asn-linked Oligosaccharide Biosynthesis

    Daniel S. Gonzalez;Khanita Karaveg;Alison S. Vandersall-Nairn;Anita Lal

  • Germ cell survival through carbohydrate-mediated interaction with Sertoli cells.

    Tomoya O. Akama;Hiroaki Nakagawa;Kazuhiro Sugihara;Sonoko Narisawa

  • Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

    Steven W. Mast;Krista Diekman;Khanita Karaveg;Ann Davis

  • Elucidation of the molecular logic by which misfolded α1-antitrypsin is preferentially selected for degradation

    Ying Wu;Matthew T. Swulius;Kelley W. Moremen;Richard N. Sifers

  • Emerging structural insights into glycosyltransferase-mediated synthesis of glycans

    Kelley W. Moremen;Robert S. Haltiwanger

  • Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.

    F Vallee;K Karaveg;A Herscovics;K.W Moremen

  • Novel purification of the catalytic domain of Golgi alpha-mannosidase II. Characterization and comparison with the intact enzyme.

    K W Moremen;O Touster;P W Robbins

  • Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans.

    K W Moremen;P W Robbins

  • Synthesis of asymmetrical multiantennary human milk oligosaccharides.

    Anthony R. Prudden;Lin Liu;Chantelle J. Capicciotti;Margreet A. Wolfert;Margreet A. Wolfert

  • An automated platform for the enzyme-mediated assembly of complex oligosaccharides.

    Tiehai Li;Lin Liu;Na Wei;Jeong-Yeh Yang

  • Cloning, Expression, Purification, and Characterization of the Human Broad Specificity Lysosomal Acid α-Mannosidase *

    Yung-Feng Liao;Anita Lal;Kelley W. Moremen

  • Golgi α-mannosidase II deficiency in vertebrate systems: implications for asparagine-linked oligosaccharide processing in mammals

    Kelley W Moremen

  • Molecular cloning and expression of cDNAs encoding human alpha-mannosidase II and a previously unrecognized alpha-mannosidase IIx isozyme.

    Masahiro Misago;Yung-Feng Liao;Shinichi Kudo;Sumiya Eto

  • Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.

    Chen Zhang;Tuo Zhang;Juan Zou;Cassandra Lynn Miller

  • Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control

    Khanita Karaveg;Aloysius Siriwardena;Wolfram Tempel;Zhi-Jie Liu

  • Substrate specificities of recombinant murine Golgi α1,2-mannosidases IA and IB and comparison with endoplasmic reticulum and Golgi processing α1,2-mannosidases

    Anita Lal;Peng Pang;Sandeep Kalelkar;Pedro A. Romero

  • Human homologs of the Xenopus oocyte cortical granule lectin XL35.

    Jin-Kyu Lee;Janet Schnee;Mabel Pang;Margreet Wolfert

Frequent Co-Authors

Geert-Jan Boons
Geert-Jan Boons University of Georgia
Richard D. Cummings
Richard D. Cummings Harvard Medical School
Lance Wells
Lance Wells University of Georgia
David F. Smith
David F. Smith Emory University
James H. Prestegard
James H. Prestegard University of Georgia
John J. Kopchick
John J. Kopchick Ohio University
Parastoo Azadi
Parastoo Azadi University of Georgia
Stephen Dalton
Stephen Dalton University of Georgia
Peng Wu
Peng Wu Scripps Research Institute
Robert J. Linhardt
Robert J. Linhardt Rensselaer Polytechnic Institute

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