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Andrea I. McClatchey

Andrea I. McClatchey

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
15571
World Ranking
14820
National Ranking
6201

Overview

Andrea I. McClatchey is affiliated with Harvard University in the United States. Their research spans multiple fields predominantly in Medicine and Biochemistry, Genetics and Molecular Biology. The scientist has contributed extensively to subfields such as Cell Biology, Neurology, Molecular Biology, Pulmonary and Respiratory Medicine, and Oncology.

Their recent research outputs include a variety of papers published in respected venues. Notable papers are:

  • Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform, 2020, Nature Communications
  • Cellular mechanisms of heterogeneity in NF2-mutant schwannoma, 2023, Nature Communications
  • EPHecting cell contact by increasing cortical tension, 2021, The Journal of Cell Biology
  • Cellular mechanisms of heterogeneity inNF2-mutant schwannoma, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions recommendation of Low Rho activity in hepatocytes prevents apical from basolateral cargo separation during trans-Golgi network to surface transport., 2021, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

The scientist frequently collaborates with several researchers in their field. Their most common co-authors include:

  • Christine Chiasson-MacKenzie
  • Shannon L. Stott
  • Jérémie Vitte
  • Ching-Hui Liu
  • Emily A. Wright

Their work is often published in a range of academic venues, with recurring publications in:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Cell Biology
  • UNC Libraries

Andrea I. McClatchey's research topics focus on several biomedical themes, including:

  • Hippo pathway signaling and YAP/TAZ
  • Cellular Mechanics and Interactions
  • Neurofibromatosis and Schwannoma Cases
  • Sarcoma Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Cancer Cells and Metastasis
  • 3D Printing in Biomedical Research

Best Publications

  • p53 status and the efficacy of cancer therapy in vivo

    SW Lowe;S Bodis;A McClatchey;L Remington

  • Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease.

    Rudolph E. Tanzi;Andrea I. McClatchey;Edward D. Lamperti;Edward D. Lamperti;Edward D. Lamperti;Lydia Villa-Komaroff;Lydia Villa-Komaroff

  • Organizing the cell cortex: the role of ERM proteins

    Richard G. Fehon;Andrea I. McClatchey;Anthony Bretscher

  • Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine.

    Ichiko Saotome;Marcello Curto;Andrea I McClatchey

  • Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

    Andrea I. McClatchey;Ichiko Saotome;Kim Mercer;Denise Crowley

  • Contact-dependent inhibition of EGFR signaling by Nf2/Merlin

    Marcello Curto;Banumathi K. Cole;Dominique Lallemand;Ching-Hui Liu

  • Spatial regulation of receptor tyrosine kinases in development and cancer

    Jessica B. Casaletto;Andrea I. McClatchey

  • The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling

    Reuben J. Shaw;J.Guillermo Paez;Marcello Curto;Ann Yaktine

  • Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin.

    Andrea I. McClatchey;Marco Giovannini

  • NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

    Dominique Lallemand;Marcello Curto;Ichiko Saotome;Marco Giovannini

  • The genetic defect in familial Alzheimer's disease is not tightly linked to the amyloid β-protein gene

    Rudolph E. Tanzi;Peter H St George-Hyslop;Jonathan L. Haines;Ronald J. Polinsky

  • Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

    Samira Benhamouche;Marcello Curto;Ichiko Saotome;Andrew B. Gladden

  • Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship

    Irina M. Shapiro;Vihren N. Kolev;Christian M. Vidal;Yuwaraj Kadariya

  • DOCK4, a GTPase activator, is disrupted during tumorigenesis.

    Vijay Yajnik;Charles Paulding;Raffaella Sordella;Andrea I. McClatchey

  • Merlin and ERM proteins: unappreciated roles in cancer development?

    Andrea I. McClatchey

  • Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex

    Andrea I. McClatchey;Richard G. Fehon

  • The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.

    A I McClatchey;I Saotome;V Ramesh;J F Gusella

  • Temperature-sensitive mutations in the III-IV cytoplasmic loop region of the skeletal muscle sodium channel gene in paramyotonia congenita.

    Andrea I. McClatchey;Peter Van den Bergh;Margaret A. Pericak-Vance;Wendy Raskind

  • YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression

    Julien Fitamant;Filippos Kottakis;Samira Benhamouche;Samira Benhamouche;Helen S. Tian

  • Contact inhibition (of proliferation) redux.

    Andrea I. McClatchey;Alpha S. K. Yap

Frequent Co-Authors

James F. Gusella
James F. Gusella Harvard University
Marco Giovannini
Marco Giovannini University of California, Los Angeles
Vijaya Ramesh
Vijaya Ramesh Harvard University
Bruce R. Korf
Bruce R. Korf University of Alabama at Birmingham
Richard G. Fehon
Richard G. Fehon University of Chicago
Marcy E. MacDonald
Marcy E. MacDonald Harvard University
D. Gareth Evans
D. Gareth Evans University of Manchester
Thomas D. Bird
Thomas D. Bird University of Washington

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