D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 109 Citations 60,990 332 World Ranking 453 National Ranking 33

Research.com Recognitions

Awards & Achievements

1992 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Neurosciences

1990 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology

1990 - Metlife Foundation Award for Medical Research in Alzheimer's Disease

1990 - Sedgwick Memorial Medal, American Public Health Association

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Biochemistry, Amyloid precursor protein, Alzheimer's disease, Amyloid and P3 peptide. His work carried out in the field of Biochemistry brings together such families of science as Presenilin and Copper. His Amyloid precursor protein research is multidisciplinary, relying on both Molecular biology and Cell biology.

His Alzheimer's disease research includes themes of Endocrinology and Degenerative disease. His Amyloid research also works with subjects such as

  • PBT2 that intertwine with fields like Clioquinol,
  • Immunology which is related to area like Western blot and Neurodegeneration. Konrad Beyreuther interconnects Transgene, Extracellular, Neuroscience and APLP1 in the investigation of issues within P3 peptide.

His most cited work include:

  • The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor (4173 citations)
  • Amyloid plaque core protein in Alzheimer disease and Down syndrome (3627 citations)
  • Soluble pool of Aβ amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease (1631 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Amyloid precursor protein, Biochemistry, Amyloid, Alzheimer's disease and P3 peptide. His Amyloid precursor protein research is multidisciplinary, incorporating elements of Molecular biology, Endocrinology and Cell biology. His Biochemistry study frequently involves adjacent topics like Alpha secretase.

Konrad Beyreuther combines topics linked to Extracellular with his work on Amyloid. His work deals with themes such as Dementia, Neuroscience, Immunology and Degenerative disease, which intersect with Alzheimer's disease. Konrad Beyreuther usually deals with P3 peptide and limits it to topics linked to Biochemistry of Alzheimer's disease and BACE1-AS.

He most often published in these fields:

  • Amyloid precursor protein (35.24%)
  • Biochemistry (34.25%)
  • Amyloid (24.02%)

What were the highlights of his more recent work (between 2000-2020)?

  • Amyloid precursor protein (35.24%)
  • Biochemistry (34.25%)
  • Amyloid (24.02%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Amyloid precursor protein, Biochemistry, Amyloid, P3 peptide and Cell biology. His Amyloid precursor protein research is included under the broader classification of Alzheimer's disease. His Alzheimer's disease study combines topics in areas such as Endocrinology, Cholesterol and Randomized controlled trial.

Konrad Beyreuther combines subjects such as Cell culture and Alpha secretase with his study of Biochemistry. His Amyloid research incorporates elements of Amino acid, Neurodegeneration and Immunology, Pathogenesis. His P3 peptide study incorporates themes from Biochemistry of Alzheimer's disease, Intracellular and Senile plaques.

Between 2000 and 2020, his most popular works were:

  • Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice (1215 citations)
  • Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo (989 citations)
  • Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial (822 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Konrad Beyreuther mostly deals with Amyloid precursor protein, Alzheimer's disease, Biochemistry, P3 peptide and Genetically modified mouse. The study incorporates disciplines such as Cell biology, Presenilin and Amyloid in addition to Amyloid precursor protein. His Alzheimer's disease research incorporates themes from Endocrinology, Cholesterol and Randomized controlled trial.

Konrad Beyreuther has included themes like Toxicity and Pharmacology in his Biochemistry study. His research in P3 peptide intersects with topics in Biochemistry of Alzheimer's disease, Peptide, Neuroscience and Senile plaques. The various areas that Konrad Beyreuther examines in his Genetically modified mouse study include Molecular biology and Pathology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Jie Kang;H.-G. Lemaire;A. Unterbeck;J. M. Salbaum.
Nature (1987)

5802 Citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome

Colin L. Masters;Gail Simms;Nicola A. Weinman;Gerd Multhaup.
Proceedings of the National Academy of Sciences of the United States of America (1985)

5232 Citations

Soluble pool of Aβ amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

Catriona A. McLean;Robert A. Cherny;Fiona W. Fraser;Stephanie J. Fuller.
Annals of Neurology (1999)

2253 Citations

Rapid induction of Alzheimer A beta amyloid formation by zinc.

Ashley I. Bush;Warren H. Pettingell;Gerd Multhaup;Marc D. Paradis.
Science (1994)

1781 Citations

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Robert A Cherny;Craig S Atwood;Michel E Xilinas;Danielle N Gray.
Neuron (2001)

1698 Citations

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

Andreas Weidemann;Gerhard König;Dirk Bunke;Peter Fischer.
Cell (1989)

1512 Citations

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons.

Mikael Simons;Patrick Keller;Bart De Strooper;Konrad Beyreuther.
Proceedings of the National Academy of Sciences of the United States of America (1998)

1448 Citations

Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

K. Fassbender;M. Simons;C. Bergmann;M. Stroick.
Proceedings of the National Academy of Sciences of the United States of America (2001)

1398 Citations

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing.

S. S. Sisodia;E. H. Koo;K. Beyreuther;A. Unterbeck.
Science (1990)

1324 Citations

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

C L Masters;G Multhaup;G Simms;J Pottgiesser.
The EMBO Journal (1985)

1235 Citations

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