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Medicine

D-Index
79
Citations
17301
World Ranking
17757
National Ranking
930

Overview

Thomas A. Bayer is affiliated with the University of Göttingen in Germany. Their research is primarily situated within the field of Medicine, with a focus on Surgery, Orthopedics and Sports Medicine, Physiology, Psychiatry and Mental Health, and Cellular and Molecular Neuroscience.

Their work covers several main topics including Orthopedic Surgery and Rehabilitation, Alzheimer's disease research and treatments, Sports injuries and prevention, Dementia and Cognitive Impairment Research, Tendon Structure and Treatment, Computational Drug Discovery Methods, and Shoulder Injury and Treatment.

Recent publications authored or co-authored by the scientist include:

  • Pyroglutamate Aβ cascade as drug target in Alzheimer's disease (2021), published in Molecular Psychiatry
  • Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits (2022), published in Scientific Reports
  • In vivo Imaging With 18F-FDG- and 18F-Florbetaben-PET/MRI Detects Pathological Changes in the Brain of the Commonly Used 5XFAD Mouse Model of Alzheimer's Disease (2020), published in Frontiers in Medicine
  • N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer's disease (2020), published in Neuropathology and Applied Neurobiology
  • Discovery of a novel pseudo β-hairpin structure of N-truncated amyloid-β for use as a vaccine against Alzheimer's disease (2021), published in Molecular Psychiatry

Frequent co-authors collaborating with Thomas A. Bayer include:

  • Yvonne Bouter
  • James L. Rudolph
  • Christoph Lutter
  • Mriganka Singh
  • Michael Uder

The scientist's work is regularly published in several journals, most notably:

  • BMJ Case Reports
  • Journal of Alzheimer s Disease
  • Journal of the American Medical Directors Association
  • Molecular Psychiatry
  • Scientific Reports

Best Publications

  • Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease.

    Sadim Jawhar;Anna Trawicka;Carolin Jenneckens;Thomas A. Bayer

  • Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ42 Accumulation in a Novel Alzheimer Transgenic Model

    Caty Casas;Nicolas Sergeant;Jean-Michel Itier;Véronique Blanchard

  • A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade.

    Oliver Wirths;Gerd Multhaup;Thomas A. Bayer

  • Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

    Oliver Wirths;Gerd Multhaup;Christian Czech;Véronique Blanchard

  • Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice

    Thomas A Bayer;Stephanie Schäfer;Andreas Simons;André Kemmling

  • Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the “Two hit hypothesis”

    Thomas A Bayer;Peter Falkai;Wolfgang Maier

  • Evidence for activation of microglia in patients with psychiatric illnesses

    Thomas A Bayer;Rolf Buslei;Laszlo Havas;Peter Falkai

  • Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease.

    Christoph Schmitz;Christoph Schmitz;Christoph Schmitz;Bart P.F. Rutten;Bart P.F. Rutten;Bart P.F. Rutten;Andrea Pielen;Stephanie Schäfer;Stephanie Schäfer

  • Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

    Maura Heverin;Nenad Bogdanovic;Dieter Lütjohann;Thomas Bayer

  • Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

    Steffen E. Storck;Sabrina Meister;Julius Nahrath;Julius N. Meißner

  • Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice

    Véronique Blanchard;Saliha Moussaoui;Christian Czech;Nathalie Touchet

  • Intracellular accumulation of amyloid-beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease

    Thomas A Bayer;Oliver Wirths

  • Homodimerization of Amyloid Precursor Protein and Its Implication in the Amyloidogenic Pathway of Alzheimer's Disease

    Stefan Scheuermann;Boris Hambsch;Lars Hesse;Joachim Stumm

  • A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease.

    Andreas Papassotiropoulos;Metin Bagli;Frank Jessen;Thomas A. Bayer

  • Pyroglutamate Amyloid-β (Aβ): A Hatchet Man in Alzheimer Disease

    Sadim Jawhar;Oliver Wirths;Thomas A. Bayer

  • Key Factors in Alzheimer's Disease: β‐amyloid Precursor Protein Processing, Metabolism and Intraneuronal Transport

    Thomas A. Bayer;Oliver Wirths;Katalin Majtényi;Tobias Hartmann

  • Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

    Zhuoran Yin;Divya Raj;Nasrin Saiepour;Debby Van Dam

  • Review of Immunological and Immunopathological Findings in Schizophrenia

    Matthias Rothermundt;Volker Arolt;Thomas A. Bayer

  • Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model.

    Oliver Wirths;Henning Breyhan;Holger Cynis;Stephan Schilling

  • Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice

    Katrin Schuessel;Stephanie Schäfer;Thomas A. Bayer;Christian Czech;Christian Czech

Frequent Co-Authors

Oliver Wirths
Oliver Wirths University of Göttingen
Gerd Multhaup
Gerd Multhaup McGill University
Peter Falkai
Peter Falkai Ludwig-Maximilians-Universität München
Konrad Beyreuther
Konrad Beyreuther Heidelberg University
William G. Honer
William G. Honer University of British Columbia
Jens Wiltfang
Jens Wiltfang University of Göttingen
Lars Lannfelt
Lars Lannfelt Uppsala University
Christoph Schmitz
Christoph Schmitz Maastricht University
Martin Ingelsson
Martin Ingelsson Uppsala University
Otmar D. Wiestler
Otmar D. Wiestler German Cancer Research Center

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