What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Dipeptidyl peptidase, Internal medicine, Endocrinology, Biochemistry and Insulin.
Dipeptidyl peptidase is a subfield of Enzyme that Hans-Ulrich Demuth explores.
His research in Internal medicine intersects with topics in Diabetes mellitus, Incretin, Glucagon-like peptide-1, Type 2 diabetes and In vivo.
His studies deal with areas such as Receptor and Biological activity, In vitro as well as Endocrinology.
Hans-Ulrich Demuth combines subjects such as Gastric inhibitory polypeptide and Peptide with his study of Receptor.
The Biochemistry study combines topics in areas such as Cell culture and Dipeptidyl peptidase-4.
His most cited work include:
- Dipeptidyl Peptidase IV Inhibitor Treatment Stimulates β-Cell Survival and Islet Neogenesis in Streptozotocin-Induced Diabetic Rats (350 citations)
- Improved glucose tolerance in Zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (309 citations)
- Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β (285 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Biochemistry, Dipeptidyl peptidase, Internal medicine, Endocrinology and Enzyme.
His study in Biochemistry is interdisciplinary in nature, drawing from both Chromatography and In vivo.
His work deals with themes such as Incretin, Blood sugar, Dipeptidyl peptidase-4, Pharmacology and Effector, which intersect with Dipeptidyl peptidase.
His work carried out in the field of Internal medicine brings together such families of science as Diabetes mellitus and Type 2 diabetes.
His Endocrinology research includes themes of Receptor, Genetically modified mouse and Neuropeptide Y receptor.
In his research on the topic of Enzyme, Amino acid, Active site, Residue, Serine and Proline is strongly related with Stereochemistry.
He most often published in these fields:
- Biochemistry (34.59%)
- Dipeptidyl peptidase (28.77%)
- Internal medicine (26.71%)
What were the highlights of his more recent work (between 2012-2021)?
- Biochemistry (34.59%)
- Cell biology (6.51%)
- Amyloid (6.51%)
In recent papers he was focusing on the following fields of study:
Hans-Ulrich Demuth mainly focuses on Biochemistry, Cell biology, Amyloid, Internal medicine and Genetically modified mouse.
His Biochemistry research focuses on In vivo and how it connects with In vitro and Peptide.
His biological study spans a wide range of topics, including Endocrinology, Cognition and Mechanism of action.
His Genetically modified mouse study combines topics in areas such as Gliosis and Amyloid precursor protein.
The concepts of his Exopeptidase activity study are interwoven with issues in Dipeptidyl peptidase and Protein precursor.
In his research, Glutamate receptor and Dipeptidyl peptidase-4 is intimately related to Cleavage, which falls under the overarching field of Dipeptidyl peptidase.
Between 2012 and 2021, his most popular works were:
- Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models. (76 citations)
- Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease (54 citations)
- An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice. (35 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Biochemistry, Alzheimer's disease, In vivo, Cell biology and Internal medicine.
His study in the field of Peptide, Enzyme, Signal transduction and Fibril is also linked to topics like Lead structure.
His Alzheimer's disease research integrates issues from Immunology, Gene isoform, Monoclonal antibody and Immunotherapy.
His In vivo study incorporates themes from In vitro and Amyloid.
His studies in Internal medicine integrate themes in fields like Serine protease, Endocrinology and Pathology.
When carried out as part of a general Endocrinology research project, his work on Dipeptidyl peptidase-4 is frequently linked to work in Population, therefore connecting diverse disciplines of study.
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