Klaus Neubert

Overview

Best Publications

• The role of dipeptidyl peptidase IV in human T lymphocyte activation. Inhibitors and antibodies against dipeptidyl peptidase IV suppress lymphocyte proliferation and immunoglobulin synthesis in vitro.

  Ekkehard Schön;Sigbert Jahn;Stephan T. Kiessig;Hans-Ulrich Demuth

  228
  Citations

• Targeting Dipeptidyl Peptidase IV (CD26) Suppresses Autoimmune Encephalomyelitis and Up-Regulates TGF-β1 Secretion In Vivo

  Andreas Steinbrecher;Dirk Reinhold;Laura Quigley;Ameer Gado

  218
  Citations

• Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV?

  J Rahfeld;M Schierhorn;B Hartrodt;K Neubert

  194
  Citations

• Dipeptidyl peptidase IV (CD 26) and aminopeptidase N (CD 13) catalyzed hydrolysis of cytokines and peptides with N-terminal cytokine sequences

  T. Hoffmann;J. Faust;K. Neubert;S. Ansorge

  170
  Citations

• Mechanism of proline-specific proteinases: (I) Substrate specificity of dipeptidyl peptidase IV from pig kidney and proline-specific endopeptidase from Flavobacterium meningosepticum.

  J. Heins;P. Welker;Chr. Schönlein;I. Born

  160
  Citations

• Dipeptidyl peptidase IV in the immune system. Effects of specific enzyme inhibitors on activity of dipeptidyl peptidase IV and proliferation of human lymphocytes.

  Ekkehard Schön;Ilona Born;Hans-Ulrich Demuth;Jürgen Faust

  156
  Citations

• Opioid peptides derived from food proteins

  Victor Brantl;Klaus Neubert

  154
  Citations

• Inhibitors of dipeptidyl peptidase IV induce secretion of transforming growth factor-beta 1 in PWM-stimulated PBMC and T cells.

  D. Reinhold;U. Bank;F. Bühling;U. Lendeckel

  148
  Citations

• Functional role of CD26 on human B lymphocytes

  Frank Bühling;Udo Junker;Dirk Reinhold;Klaus Neubert

  148
  Citations

• Dipeptidyl peptidase IV in human T lymphocytes. Impaired induction of interleukin 2 and gamma interferon due to specific inhibition of dipeptidyl peptidase IV.

  E. Schön;H.‐U. Demuth;E. Eichmann;H.‐J. Horst

  139
  Citations

• Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation.

  Anja Thielitz;Dirk Reinhold;Robert Vetter;Ute Bank

  114
  Citations

• Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts.

  Anja Thielitz;Robert W. Vetter;Bianca Schultze;Sabine Wrenger

  113
  Citations

• The renal type H+/peptide symporter PEPT2: structure-affinity relationships

  A. Biegel;I. Knütter;B. Hartrodt;S. Gebauer

  113
  Citations

• TGF-β1-Mediated Control of Central Nervous System Inflammation and Autoimmunity through the Inhibitory Receptor CD26

  Vera Preller;Annegret Gerber;Sabine Wrenger;Mauro Togni

  111
  Citations

• Derivatives of β-casomorphins with high analgesic potency

  Hansjuergen Matthies;Holger Stark;Bianka Hartrodt;Heide-Linde Ruethrich

  109
  Citations

• Three-Dimensional Quantitative Structure−Activity Relationship Analyses of β-Lactam Antibiotics and Tripeptides as Substrates of the Mammalian H+/Peptide Cotransporter PEPT1

  Annegret Biegel;Sabine Gebauer;Bianka Hartrodt;Matthias Brandsch

  105
  Citations

• The role of dipeptidyl peptidase IV (DP IV) enzymatic activity in T cell activation and autoimmunity.

  Dirk Reinhold;Thilo Kähne;Andreas Steinbrecher;Sabine Wrenger

  101
  Citations

• Serotonin, l-tryptophan, and tryptamine are effective inhibitors of the amino acid transport system PAT1

  Linda Metzner;Gabor Kottra;Klaus Neubert;Hannelore Daniel

  100
  Citations

• Inhibitors of dipeptidyl peptidase IV/CD26 suppress activation of human MBP-specific CD4+ T cell clones

  Dirk Reinhold;Dirk Reinhold;Bernhard Hemmer;Bruno Gran;Ilona Born

  98
  Citations

• Dipeptidyl Peptidase IV (CD26) on Human Lymphocytes. Synthetic Inhibitors of and Antibodies against Dipeptidyl Peptidase IV Suppress the Proliferation of Pokeweed Mitogen-Stimulated Peripheral Blood Mononuclear Cells, and IL-2 and IL-6 Production

  Dirk Reinhold;Ute Bank;Frank Bühling;Klaus Neubert

  97
  Citations