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Geoffrey W. McCaughan

Geoffrey W. McCaughan

D-Index & Metrics

Medicine

D-Index
101
Citations
35970
World Ranking
8014
National Ranking
237

Overview

Geoffrey W. McCaughan is affiliated with the University of Sydney in Australia. Their research primarily focuses on medicine, with a strong emphasis on hepatology, surgery, epidemiology, oncology, and immunology. This body of work addresses multiple aspects of liver diseases, organ transplantation techniques, and related outcomes.

The scientist has contributed extensively to key topics in their field, including:

  • Liver Disease and Transplantation
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease Diagnosis and Treatment
  • Renal Transplantation Outcomes and Treatments
  • Peptidase Inhibition and Analysis
  • Organ Donation and Transplantation
  • Hepatocellular Carcinoma Treatment and Prognosis

McCaughan's recent publications demonstrate a focus on liver disease and immunological responses related to hepatocellular carcinoma and the impact of comorbidities on COVID-19 severity. Notable papers include:

  • Gut microbiota impact on the peripheral immune response in non-alcoholic fatty liver disease related hepatocellular carcinoma, 2021, Nature Communications
  • Animal and translational models of SARS-CoV-2 infection and COVID-19, 2020, Mucosal Immunology
  • COVID-19 and comorbidities: A role for dipeptidyl peptidase 4 (DPP4) in disease severity?, 2020, Journal of Diabetes
  • Current perspectives on the tumor microenvironment in hepatocellular carcinoma, 2020, Hepatology International
  • Cardiovascular mortality following liver transplantation: predictors and temporal trends over 30 years, 2020, European Heart Journal - Quality of Care and Clinical Outcomes

Their research outputs are frequently published in selected venues, reflecting a focused area of expertise. These venues include:

  • Liver Transplantation
  • Journal of Hepatology
  • Transplantation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Transplantation

McCaughan has collaborated regularly with several coauthors, indicating a network of ongoing research partnerships. Frequent collaborators include Ken Liu, Simone I. Strasser, Carlo Pulitanò, Avik Majumdar, and Michael Crawford.

Best Publications

  • Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture

    M V Apte;P S Haber;T L Applegate;I D Norton

  • Insulin resistance is associated with chronic hepatitis C and virus infection fibrosis progression

    Jason M Hui;Archana Sud;Geoffrey C Farrell;Priyanka Bandara

  • Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis

    M V Apte;P S Haber;S J Darby;S C Rodgers

  • A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt

    William Sievert;Ibrahim Altraif;Homie A. Razavi;Ayman Abdo

  • Hepascore: An Accurate Validated Predictor of Liver Fibrosis in Chronic Hepatitis C Infection

    Leon A. Adams;Max Bulsara;Enrico Rossi;Bastiaan DeBoer

  • Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2005 update.

    Yun-Fan Liaw;Nancy Leung;Richard Guan;George K.K. Lau

  • 2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.

    A J Demetris;C Bellamy;S G Hübscher;J O'Leary

  • Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines

    J Napoli;G A Bishop;P H McGuinness;D M Painter

  • Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial

    Michael Manns;Didier Samuel;Edward J Gane;David Mutimer

  • Activation of Pancreatic Stellate Cells in Human and Experimental Pancreatic Fibrosis

    Paul S. Haber;Gregory W. Keogh;Minoti V. Apte;Corey S. Moran

  • CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes.

    M. D. Gorrell;V. Gysbers;G. W. McCaughan

  • Real‐time reverse transcriptase–polymerase chain reaction (RT–PCR) for measurement of cytokine and growth factor mRNA expression with fluorogenic probes or SYBR Green I

    Jian Lin Yin;Nicholas A Shackel;Amany Zekry;Peter H McGuinness

  • Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells

    Minoti V. Apte;Phoebe A. Phillips;Roger G. Fahmy;Samantha J. Darby

  • Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis

    Miriam T. Levy;Geoffrey W. McCaughan;Catherine A. Abbott;John E. Park

  • The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity

    David G. Bowen;Monica Zen;Lauren Holz;Thomas Davis

  • Combination low-dose hepatitis B immune globulin and lamivudine therapy provides effective prophylaxis against posttransplantation hepatitis B

    Peter W. Angus;Geoffrey W. McCaughan;Edward J. Gane;Darryl H.G. Crawford

  • Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant hepatitis B: final long-term results.

    Eugene Schiff;Cjing Lung Lai;Stephanos Hadziyannis;Peter Nuehaus

  • Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8.

    Catherine A. Abbott;Denise M. T. Yu;Erica Woollatt;Grant R. Sutherland

  • Lamivudine plus low-dose hepatitis B immunoglobulin to prevent recurrent hepatitis B following liver transplantation.

    Edward J. Gane;Peter W. Angus;Simone Strasser;Darrell H.G. Crawford

  • T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells

    Alessandra Warren;David G. Le Couteur;Robin Fraser;David G. Bowen

Frequent Co-Authors

Mark D. Gorrell
Mark D. Gorrell University of Sydney
David Bowen
David Bowen Royal Prince Alfred Hospital
Patrick Bertolino
Patrick Bertolino Centenary Institute of Cancer Medicine and Cell Biology
Jacob George
Jacob George University of Sydney
James G. Kench
James G. Kench Royal Prince Alfred Hospital
Peter W Angus
Peter W Angus Austin Hospital
Georgia A. Bishop
Georgia A. Bishop The Ohio State University
Gregory J. Dore
Gregory J. Dore University of New South Wales
John F. Thompson
John F. Thompson University of Sydney
Darrell H. G. Crawford
Darrell H. G. Crawford University of Queensland

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