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Immunology

D-Index
46
Citations
8136
World Ranking
4620
National Ranking
201

Overview

Patrick Bertolino is affiliated with the Centenary Institute of Cancer Medicine and Cell Biology in Australia. Their research primarily spans the fields of immunology and microbiology, with additional contributions to medicine. The main subfields of study for Bertolino include immunology, public health, environmental and occupational health, molecular biology, surgery, and parasitology.

Key topics in Bertolino's research encompass:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • Malaria Research and Control
  • Immune cells in cancer
  • Parasites and Host Interactions
  • Liver physiology and pathology

The scientist has authored several recent papers, including:

  • A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice (2020), published in Cell Host & Microbe
  • ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis (2021), published in JHEP Reports
  • mRNA vaccine against malaria tailored for liver-resident memory T cells (2023), published in Nature Immunology
  • Glycolipid-peptide vaccination induces liver-resident memory CD8 + T cells that protect against rodent malaria (2020), published in Science Immunology
  • Apoptotic cell fragments locally activate tingible body macrophages in the germinal center (2023), published in Cell

Bertolino frequently collaborates with several coauthors, including:

  • David G. Bowen
  • Kieran English
  • William R. Heath
  • Maria N. de Menezes
  • Lauren E. Holz

The scientist's work has appeared regularly in specific publication venues. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunology and Cell Biology
  • Blood
  • Transplantation
  • Cell Host & Microbe

Best Publications

  • TLR4 activation mediates kidney ischemia/reperfusion injury

    Huiling Wu;Gang Chen;Kate R. Wyburn;Jianlin Yin

  • Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.

    Daniel Fernandez-Ruiz;Wei Yi Ng;Wei Yi Ng;Lauren E Holz;Joel Z Ma

  • The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity

    David G. Bowen;Monica Zen;Lauren Holz;Thomas Davis

  • T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells

    Alessandra Warren;David G. Le Couteur;Robin Fraser;David G. Bowen

  • HEPATOCYTES INDUCE FUNCTIONAL ACTIVATION OF NAIVE CD8+ T LYMPHOCYTES BUT FAIL TO PROMOTE SURVIVAL

    Patrick Bertolino;Marie Claude Trescol-Biémont;Chantal Rabourdin-Combe

  • Antigen-specific primary activation of CD8+ T cells within the liver.

    Patrick Bertolino;David G. Bowen;Geoffrey W. McCaughan;Barbara Fazekas de St. Groth

  • Autocrine IL‐10 impairs dendritic cell (DC)‐derived immune responses to mycobacterial infection by suppressing DC trafficking to draining lymph nodes and local IL‐12 production

    Caroline Demangel;Patrick Bertolino;Warwick J. Britton;Warwick J. Britton

  • A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment

    Frederic Sierro;Maximilien Evrard;Simone Rizzetto;Michelle Melino

  • Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b).

    Christopher J. Greenhalgh;Patrick Bertolino;Sylvia L. Asa;Donald Metcalf

  • Role of primary intrahepatic T-cell activation in the 'liver tolerance effect'.

    Patrick Bertolino;Geoffrey W McCaughan;David G Bowen

  • Hepatocyte entry leads to degradation of autoreactive CD8 T cells

    Volker Benseler;Alessandra Warren;Michelle Vo;Lauren E. Holz

  • Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids.

    H. A. McNamara;Y. Cai;M. V. Wagle;Y. Sontani

  • The liver: a special case in transplantation tolerance.

    Volker Benseler;Geoffrey W. McCaughan;Hans J. Schlitt;G. Alex Bishop

  • EXPRESSION OF TWO T CELL RECEPTOR ALPHA CHAINS ON THE SURFACE OF NORMAL MURINE T CELLS

    William R. Heath;Francis R. Carbone;Patrick Bertolino;Jannice Kelly

  • Peripheral deletion of autoreactive CD8+ T cells in transgenic mice expressing H-2Kb in the liver.

    Patrick Bertolino;William R. Heath;Charles L. Hardy;Grant Morahan

  • Intrahepatic immunity: a tale of two sites?

    David G. Bowen;Geoffrey W. McCaughan;Patrick Bertolino

  • Death by neglect as a deletional mechanism of peripheral tolerance

    Patrick Bertolino;Marie-Claude Trescol-Biémont;Joëlle Thomas;Barbara Fazekas de St Groth

  • Intrahepatic murine CD8 T cell activation associates with a distinct phenotype leading to Bim-dependent death

    Lauren E. Holz;Volker Benseler;Volker Benseler;David G. Bowen;Philippe Bouillet

  • Suppressor of cytokine signaling-1 attenuates the duration of interferon gamma signal transduction in vitro and in vivo.

    Marta Brysha;Jian-Guo Zhang;Patrick Bertolino;Jason E. Corbin

  • An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis

    Ben Roediger;Quintin Lee;Shweta Tikoo;Joanna C.A. Cobbin

  • Erratum: Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection (Immunity (2016) 45(4) (889–902), (S1074761316303351), (10.1016/j.immuni.2016.08.011))

    Daniel Fernandez-Ruiz;Wei Yi Ng;Wei Yi Ng;Lauren E. Holz;Joel Z. Ma

Frequent Co-Authors

David Bowen
David Bowen Royal Prince Alfred Hospital
Geoffrey W. McCaughan
Geoffrey W. McCaughan University of Sydney
William R. Heath
William R. Heath University of Melbourne
Ian E. Alexander
Ian E. Alexander University of Sydney
David G. Le Couteur
David G. Le Couteur University of Sydney
Irina Caminschi
Irina Caminschi Monash University
Chantal Rabourdin-Combe
Chantal Rabourdin-Combe École Normale Supérieure de Lyon
Geoffrey I. McFadden
Geoffrey I. McFadden University of Melbourne
Wolfgang Weninger
Wolfgang Weninger Medical University of Vienna
Jennifer R. Gamble
Jennifer R. Gamble University of Sydney

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