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Jennifer R. Gamble

Jennifer R. Gamble

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
22673
World Ranking
4753
National Ranking
112

Overview

Jennifer R. Gamble is affiliated with the University of Sydney in Australia. Their research activity spans multiple fields within medicine and biological sciences, with a strong focus on molecular and cellular mechanisms of disease as well as immunology and neurology.

The scientist's primary fields of study include Medicine and Biochemistry, Genetics and Molecular Biology. Within these, their notable subfields of research are Cancer Research, Molecular Biology, Neurology, Immunology, and Infectious Diseases.

The main topics addressed in their publications reflect a concentration on disease processes and molecular regulation, including:

  • Cancer, Hypoxia, and Metabolism
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • MicroRNA in disease regulation
  • Cell Adhesion Molecules Research
  • Cancer-related molecular mechanisms research
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies

Recent papers authored or co-authored by Jennifer R. Gamble demonstrate involvement in both infectious disease research and molecular biology topics. Selected publications include:

  • Animal and translational models of SARS-CoV-2 infection and COVID-19, 2020, Mucosal Immunology
  • Development of Novel Therapeutics Targeting the Blood-Brain Barrier: From Barrier to Carrier, 2021, Advanced Science
  • Vascular senescence and leak are features of the early breakdown of the blood-brain barrier in Alzheimer's disease models, 2023, GeroScience
  • Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2, 2020, Proceedings of the National Academy of Sciences
  • Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice, 2020, PLoS Biology

The researcher's frequent publication venues illustrate a diversity of scientific outlets, including bioRxiv (Cold Spring Harbor Laboratory), Mucosal Immunology, Advanced Science, GeroScience, and JHEP Reports.

Jennifer R. Gamble has collaborated regularly with several co-authors, featuring repeated joint publications with:

  • Paul Coleman
  • Mathew A. Vadas
  • Ka Ka Ting
  • Jinbiao Chen
  • Geoffrey W. McCaughan

This profile reflects a scientific career characterized by research into molecular pathways of disease, immune system mechanisms, and translational approaches addressing conditions such as cancer, neurodegeneration, and infectious diseases including COVID-19.

Best Publications

  • Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

    J R Gamble;J M Harlan;S J Klebanoff;M A Vadas

  • Recombinant human interleukin 5 is a selective activator of human eosinophil function.

    Angel F. Lopez;Colin J. Sanderson;Jennifer R. Gamble;Hugh D. Campbell

  • Stimulation of neutrophils by tumor necrosis factor.

    S J Klebanoff;M A Vadas;J M Harlan;L H Sparks

  • High-Density Lipoproteins Inhibit Cytokine-Induced Expression of Endothelial Cell Adhesion Molecules

    Gillian W. Cockerill;Kerry-Anne Rye;Jennifer R. Gamble;Mathew Alexander Vadas

  • Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

    A F Lopez;D J Williamson;J R Gamble;C G Begley

  • Angiopoietin-1 Is an Antipermeability and Anti-Inflammatory Agent In Vitro and Targets Cell Junctions

    Jennifer R. Gamble;Jenny Drew;Libby Trezise;Anne Underwood

  • An oncogenic role of sphingosine kinase

    Pu Xia;Jennifer R. Gamble;Lijun Wang;Stuart M. Pitson

  • Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway.

    Pu Xia;Jennifer R. Gamble;Kerry-Anne Rye;Lijun Wang

  • Characterization of GMP-140 (P-selectin) as a circulating plasma protein.

    L C Dunlop;M P Skinner;L J Bendall;E J Favaloro

  • Activation of Sphingosine Kinase by Tumor Necrosis Factor-α Inhibits Apoptosis in Human Endothelial Cells

    Pu Xia;Lijun Wang;Jennifer R. Gamble;Mathew Alexander Vadas

  • Roles of Cyclooxygenase (COX)-1 and COX-2 in Prostanoid Production by Human Endothelial Cells: Selective Up-Regulation of Prostacyclin Synthesis by COX-2

    Gillian E. Caughey;Leslie G. Cleland;Peter S. Penglis;Jennifer R. Gamble

  • Sphingosine Kinase Interacts with TRAF2 and Dissects Tumor Necrosis Factor-α Signaling

    Pu Xia;Lijun Wang;Paul A. B. Moretti;Nathaniel Albanese

  • Prevention of activated neutrophil adhesion to endothelium by soluble adhesion protein GMP140.

    Jennifer R. Gamble;Michael P. Skinner;Michael C. Berndt;Mathew A. Vadas

  • High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL.

    Pu Xia;Mathew Alexander Vadas;Kerry-Anne Rye;Philip John Barter

  • Endothelial Adhesiveness for Blood Neutrophils Is Inhibited by Transforming Growth Factor-β

    Jennifer R. Gamble;Matthew A. Vadas

  • Transforming growth factor-beta inhibits E-selectin expression on human endothelial cells.

    J R Gamble;Y Khew-Goodall;M A Vadas

  • Angiogenesis: models and modulators.

    Gillian W. Cockerill;Jennifer R. Gamble;Mathew A. Vadas

  • Regulation of in vitro capillary tube formation by anti-integrin antibodies.

    J R Gamble;L J Matthias;G Meyer;P Kaur

  • Factors Influencing the Ability of HDL to Inhibit Expression of Vascular Cell Adhesion Molecule-1 in Endothelial Cells

    Dale T. Ashby;Kerry-Anne Rye;Moira A. Clay;Mathew A. Vadas

  • Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression.

    M A Vadas;J F Miller;I F McKenzie;S E Chism

Frequent Co-Authors

Mathew A. Vadas
Mathew A. Vadas University of Sydney
Angel F. Lopez
Angel F. Lopez University of South Australia
Geoffrey W. McCaughan
Geoffrey W. McCaughan University of Sydney
Kerry-Anne Rye
Kerry-Anne Rye University of New South Wales
Stuart M. Pitson
Stuart M. Pitson University of South Australia
Philip J. Barter
Philip J. Barter University of New South Wales
Patrick Bertolino
Patrick Bertolino Centenary Institute of Cancer Medicine and Cell Biology
Michael C. Berndt
Michael C. Berndt Curtin University
John M. Harlan
John M. Harlan University of Washington
Gregory J. Goodall
Gregory J. Goodall University of Adelaide

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