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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
37780
World Ranking
1654
National Ranking
38

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award
  • 2015 - Fellow of the Australian Academy of Health and Medical Science

Overview

Mathew A. Vadas is affiliated with the University of Sydney in Australia and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans multiple subfields including Molecular Biology, Cancer Research, Immunology, Neurology, and Physiology.

Key topics in their research include:

  • Sphingolipid Metabolism and Signaling
  • Cancer-related molecular mechanisms research
  • Cancer, Hypoxia, and Metabolism
  • Telomeres, Telomerase, and Senescence
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Immune cells in cancer
  • Angiogenesis and VEGF in Cancer

Mathew A. Vadas has contributed to several papers, with recent examples being:

  • "Vascular senescence and leak are features of the early breakdown of the blood-brain barrier in Alzheimer's disease models," 2023, published in GeroScience
  • "Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2," 2020, published in Proceedings of the National Academy of Sciences
  • "Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice," 2020, published in PLoS Biology
  • "The aging endothelium," 2021, published in Vascular Biology
  • "The VE-Cadherin/β-catenin signalling axis regulates immune cell infiltration into tumours," 2020, published in Cancer Letters

The frequent coauthors collaborating with Mathew A. Vadas include:

  • Jennifer R. Gamble
  • Ka Ka Ting
  • Paul Coleman
  • Jinbiao Chen
  • Yang Zhao

Their work is often published in journals such as:

  • Journal of Translational Medicine
  • GeroScience
  • Proceedings of the National Academy of Sciences
  • PLoS Biology
  • Vascular Biology

Mathew A. Vadas was recognized as a Fellow of the Australian Academy of Health and Medical Science in 2015.

Best Publications

  • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.

    Philip A. Gregory;Andrew G. Bert;Emily L. Paterson;Simon C. Barry

  • Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

    J R Gamble;J M Harlan;S J Klebanoff;M A Vadas

  • Recombinant human interleukin 5 is a selective activator of human eosinophil function.

    Angel F. Lopez;Colin J. Sanderson;Jennifer R. Gamble;Hugh D. Campbell

  • Stimulation of neutrophils by tumor necrosis factor.

    S J Klebanoff;M A Vadas;J M Harlan;L H Sparks

  • High-Density Lipoproteins Inhibit Cytokine-Induced Expression of Endothelial Cell Adhesion Molecules

    Gillian W. Cockerill;Kerry-Anne Rye;Jennifer R. Gamble;Mathew Alexander Vadas

  • Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

    A F Lopez;D J Williamson;J R Gamble;C G Begley

  • Angiopoietin-1 Is an Antipermeability and Anti-Inflammatory Agent In Vitro and Targets Cell Junctions

    Jennifer R. Gamble;Jenny Drew;Libby Trezise;Anne Underwood

  • Activation of sphingosine kinase 1 by ERK1/2‐mediated phosphorylation

    Stuart M. Pitson;Paul A.B. Moretti;Julia R. Zebol;Helen E. Lynn

  • Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor.

    Metcalf D;Begley Cg;Johnson Gr;Nicola Na

  • An oncogenic role of sphingosine kinase

    Pu Xia;Jennifer R. Gamble;Lijun Wang;Stuart M. Pitson

  • Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway.

    Pu Xia;Jennifer R. Gamble;Kerry-Anne Rye;Lijun Wang

  • A New Method for the Purification of Human Eosinophils and Neutrophils, and a Comparison of the Ability of These Cells to Damage Schistosomula of Schistosoma Mansoni

    Mathew A. Vadas;John R. David;Anthony Butterworth;Nancy T. Pisani

  • Characterization of GMP-140 (P-selectin) as a circulating plasma protein.

    L C Dunlop;M P Skinner;L J Bendall;E J Favaloro

  • Activation of Sphingosine Kinase by Tumor Necrosis Factor-α Inhibits Apoptosis in Human Endothelial Cells

    Pu Xia;Lijun Wang;Jennifer R. Gamble;Mathew Alexander Vadas

  • Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins.

    J P Lévesque;D I Leavesley;S Niutta;M Vadas

  • Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factors.

    CG Begley;CG Begley;AF Lopez;AF Lopez;NA Nicola;NA Nicola;DJ Warren;DJ Warren

  • Sphingosine Kinase Interacts with TRAF2 and Dissects Tumor Necrosis Factor-α Signaling

    Pu Xia;Lijun Wang;Paul A. B. Moretti;Nathaniel Albanese

  • Prevention of activated neutrophil adhesion to endothelium by soluble adhesion protein GMP140.

    Jennifer R. Gamble;Michael P. Skinner;Michael C. Berndt;Mathew A. Vadas

  • High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL.

    Pu Xia;Mathew Alexander Vadas;Kerry-Anne Rye;Philip John Barter

  • Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling

    Stuart M. Pitson;Pu Xia;Tamara M. Leclercq;Paul A.B. Moretti

Frequent Co-Authors

Jennifer R. Gamble
Jennifer R. Gamble University of Sydney
Angel F. Lopez
Angel F. Lopez University of South Australia
Stuart M. Pitson
Stuart M. Pitson University of South Australia
Gregory J. Goodall
Gregory J. Goodall University of Adelaide
Kerry-Anne Rye
Kerry-Anne Rye University of New South Wales
Philip J. Barter
Philip J. Barter University of New South Wales
Geoffrey W. McCaughan
Geoffrey W. McCaughan University of Sydney
Peter N. Cockerill
Peter N. Cockerill University of Birmingham
Michael C. Berndt
Michael C. Berndt Curtin University
Thomas J. Gonda
Thomas J. Gonda University of South Australia

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