World's Best Scientists 2026 revealed!
Anne-Marie Lambeir

Anne-Marie Lambeir

D-Index & Metrics

Chemistry

D-Index
59
Citations
11529
World Ranking
10217
National Ranking
132

Biology and Biochemistry

D-Index
59
Citations
11840
World Ranking
12599
National Ranking
233

Overview

Anne-Marie Lambeir is affiliated with the University of Antwerp in Belgium. Their research contributions span across medicine and biochemistry, genetics, and molecular biology, with a focus on molecular biology, oncology, cancer research, cellular and molecular neuroscience, and immunology.

The scientist's work extensively covers several main topics, including:

  • Peptidase Inhibition and Analysis
  • Protease and Inhibitor Mechanisms
  • Neuropeptides and Animal Physiology
  • Signaling Pathways in Disease
  • Parkinson's Disease Mechanisms and Treatments
  • Electrochemical sensors and biosensors
  • Cancer, Hypoxia, and Metabolism

Anne-Marie Lambeir has published in various scientific venues. The most frequent publication outlets include:

  • Journal of Medicinal Chemistry
  • International Journal of Molecular Sciences
  • Scientific Reports
  • Frontiers in Chemistry
  • FEBS Letters

Recent papers authored or co-authored by Anne-Marie Lambeir include:

  • "Metal ions shape α-synuclein", 2020, Scientific Reports
  • "Small molecule 3PO inhibits glycolysis but does not bind to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3)", 2020, FEBS Letters
  • "A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation", 2020, Scientific Reports
  • "The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy", 2020, Biomedicine & Pharmacotherapy
  • "In Vitro and In Situ Activity-Based Labeling of Fibroblast Activation Protein with UAMC1110-Derived Probes", 2021, Frontiers in Chemistry

Their frequent co-authors include:

  • Ingrid De Meester
  • Pieter Van der Veken
  • Koen Augustyns
  • Maya Berg
  • Roos Van Elzen

Best Publications

  • Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.

    Anne-Marie Lambeir;Christine Durinx;Simon Scharpé;Ingrid De Meester

  • Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection.

    Paul Proost;Ingrid De Meester;Dominique Schols;Sofie Struyf

  • Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides.

    Christine Durinx;Anne-Marie Lambeir;Eugène Bosmans;Jean-Bernard Falmagne

  • Kinetic Investigation of Chemokine Truncation by CD26/Dipeptidyl Peptidase IV Reveals a Striking Selectivity within the Chemokine Family

    Anne-Marie Lambeir;Paul Proost;Christine Durinx;Gunther Bal

  • Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties

    Paul Proost;Evemie Schutyser;Patricia Menten;Sofie Struyf

  • Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

    Koen Jansen;Leen Heirbaut;Robert Verkerk;Jonathan D Cheng

  • Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form.

    Inger Brandt;Anne-Marie Lambeir;Jean-Marie Ketelslegers;Marc Vanderheyden

  • Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold.

    Koen Jansen;Leen Heirbaut;Jonathan D. Cheng;Jurgen Joossens

  • Spectral properties of the higher oxidation states of prostaglandin H synthase.

    Lambeir Am;Markey Cm;Dunford Hb;Marnett Lj

  • The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis.

    Yannick Waumans;Lesley Baerts;Kaat Kehoe;Anne-Marie Lambeir

  • Truncation of Macrophage-derived Chemokine by CD26/ Dipeptidyl-Peptidase IV beyond Its Predicted Cleavage Site Affects Chemotactic Activity and CC Chemokine Receptor 4 Interaction

    Paul Proost;Sofie Struyf;Dominique Schols;Ghislain Opdenakker

  • The unique properties of dipeptidyl-peptidase IV (DPP IV / CD26) and the therapeutic potential of DPP IV inhibitors.

    K Augustyns;G Bal;G Thonus;A Belyaev

  • Regulation of intestinal permeability: The role of proteases.

    Hanne Van Spaendonk;Hannah Ceuleers;Leonie Witters;Eveline Patteet

  • Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).

    Inger Brandt;Jurgen Joossens;Xin Chen;Marie-Berthe Maes

  • Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.

    Jenkins J;Janin J;Rey F;Chiadmi M

  • Fluoro-Olefins as Peptidomimetic Inhibitors of Dipeptidyl Peptidases

    Pieter Van der Veken;Kristel Senten;István Kertèsz;Ingrid De Meester

  • Serine peptidase modulators

    Simon Scharpe;Ingrid De Meester;Anne-Marie Lambeir;Koen Augustyns

  • A fluorescence stopped flow study of colchicine binding to tubulin.

    A Lambeir;Yves Engelborghs

  • Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power

    John C. Williams;Johan P. Zeelen;Gitte Neubauer;Gert Vriend

  • Kinetics of the reaction of compound II of horseradish peroxidase with hydrogen peroxide to form compound III

    Suara A. Adediran;Anne-Marie Lambeir

  • Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors

    A. Belyaev;Xuemei Zhang;K. Augustyns;A.-M. Lambeir

Frequent Co-Authors

Koen Augustyns
Koen Augustyns University of Antwerp
Ingrid De Meester
Ingrid De Meester University of Antwerp
Simon Scharpé
Simon Scharpé University of Antwerp
Paul Proost
Paul Proost KU Leuven
Rik K. Wierenga
Rik K. Wierenga University of Oulu
Louis Maes
Louis Maes University of Antwerp
Frank Sobott
Frank Sobott University of Leeds
Jo Van Damme
Jo Van Damme Rega Institute for Medical Research
Erik Fransen
Erik Fransen University of Antwerp
Paul Cos
Paul Cos University of Antwerp

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