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Biology and Biochemistry

D-Index
49
Citations
9511
World Ranking
17978
National Ranking
626

Overview

Wayne S. Sossin is affiliated with the Montreal Neurological Institute and Hospital in Canada. Their research spans multiple fields primarily in Biochemistry, Genetics and Molecular Biology as well as Neuroscience. Within these broad areas, they focus notably on Molecular Biology, Cellular and Molecular Neuroscience, Cell Biology, Cognitive Neuroscience, and Genetics.

Their main topics of work include:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Neurobiology and Insect Physiology Research
  • Neuroscience and Neuropharmacology Research
  • Calpain Protease Function and Regulation
  • Genetics and Neurodevelopmental Disorders
  • Memory and Neural Mechanisms

Recent scientific publications demonstrate the diversity and focus of their research. Some notable papers are:

  • "Ribosomes in RNA Granules Are Stalled on mRNA Sequences That Are Consensus Sites for FMRP Association" (2023), published in the Journal of Neuroscience
  • "Biallelic variants in the small optic lobe calpain CAPN15 are associated with congenital eye anomalies, deafness and other neurodevelopmental deficits" (2020), published in Human Molecular Genetics
  • "The evolution of synaptic and cognitive capacity: Insights from the nervous system transcriptome of Aplysia" (2022), published in Proceedings of the National Academy of Sciences
  • "Terminological and Epistemological Issues in Current Memory Research" (2020), published in Frontiers in Molecular Neuroscience
  • "The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner" (2024), published in Proceedings of the National Academy of Sciences

Frequent collaborators include:

  • Mina N. Anadolu
  • Jingyu Sun
  • Joaquín Ortega
  • Congyao Zha
  • Senthilkumar Kailasam

Their work has appeared regularly in several scientific venues, with the greatest number of publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Journal of Neuroscience
  • Human Molecular Genetics
  • Frontiers in Molecular Neuroscience

Best Publications

  • Translational control of long-lasting synaptic plasticity and memory.

    Mauro Costa-Mattioli;Wayne S. Sossin;Eric Klann;Nahum Sonenberg

  • eIF2α Phosphorylation Bidirectionally Regulates the Switch from Short- to Long-Term Synaptic Plasticity and Memory

    Mauro Costa-Mattioli;Delphine Gobert;Elad Stern;Karine Gamache

  • Translational control of hippocampal synaptic plasticity and memory by the eIF2α kinase, GCN2

    Mauro Costa-Mattioli;Delphine Gobert;Heather Harding;Barbara Herdy

  • Differential Sorting of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Hippocampal Neurons

    S. Javad Mowla;Sangeeta Pareek;Hooman F. Farhadi;Kevin Petrecca

  • Characterization of an RNA Granule from Developing Brain

    George Elvira;Sylwia Wasiak;Vanessa Blandford;Xin-Kang Tong

  • Synapse- and stimulus-specific local translation during long-term neuronal plasticity.

    Dan Ohtan Wang;Sang Mok Kim;Yali Zhao;Hongik Hwang

  • Cellular and molecular biology of neuropeptide processing and packaging

    Wayne S. Sossin;Joseph M. Fisher;Richard H. Scheller

  • Multiple neuropeptides derived from a common precursor are differentially packaged and transported.

    Joseph M. Fisher;Wayne Sossin;Robert Newcomb;Richard H. Scheller

  • Reactivation of stalled polyribosomes in synaptic plasticity

    Tyson E. Graber;Sarah Hébert-Seropian;Arkady Khoutorsky;Alexandre David

  • Identification of the Major Synaptojanin-binding Proteins in Brain

    Elaine de Heuvel;Alexander W. Bell;Antoine R. Ramjaun;Kenny Wong

  • Neurons Promote the Translocation of Peripheral Myelin Protein 22 into Myelin

    Pareek S;Notterpek L;Snipes Gj;Naef R

  • Dale's hypothesis revisited: different neuropeptides derived from a common prohormone are targeted to different processes

    Wayne S. Sossin;Alejandro Sweet-Cordero;Richard H. Scheller

  • Intracellular trafficking of RNA in neurons.

    Wayne S. Sossin;Luc DesGroseillers

  • Protein kinase C activation promotes microtubule advance in neuronal growth cones by increasing average microtubule growth lifetimes.

    Nurul Kabir;Andrew W. Schaefer;Arash Nakhost;Wayne S. Sossin

  • A recollection of mTOR signaling in learning and memory.

    Tyson E. Graber;Patrick K. McCamphill;Wayne S. Sossin

  • Sorting within the regulated secretory pathway occurs in the trans-Golgi network.

    W S Sossin;J M Fisher;R H Scheller

  • Isoform specificity of protein kinase Cs in synaptic plasticity.

    Wayne S. Sossin

  • Peptidergic modulation of neuronal circuitry controlling feeding in Aplysia

    WS Sossin;Kirk;RH Scheller

  • Ca2+-independent protein kinase C Apl II mediates the serotonin-induced facilitation at depressed aplysia sensorimotor synapses.

    Frédéric Manseau;Xiaotang Fan;Tina Hueftlein;Wayne S. Sossin

  • Translational Control in the Brain in Health and Disease.

    Wayne S. Sossin;Mauro Costa-Mattioli

Frequent Co-Authors

Jean-Claude Lacaille
Jean-Claude Lacaille University of Montreal
Vincent F. Castellucci
Vincent F. Castellucci University of Montreal
Luc DesGroseillers
Luc DesGroseillers University of Montreal
James H. Schwartz
James H. Schwartz Columbia University
Nahum Sonenberg
Nahum Sonenberg McGill University
Samuel Schacher
Samuel Schacher Columbia University
David L. Glanzman
David L. Glanzman University of California, Los Angeles
Kelsey C. Martin
Kelsey C. Martin University of California, Los Angeles
Peter S. McPherson
Peter S. McPherson Montreal Neurological Institute and Hospital

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