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Catriona McLean

Catriona McLean

D-Index & Metrics

Medicine

D-Index
107
Citations
50548
World Ranking
6165
National Ranking
171

Overview

Catriona McLean is affiliated with The Alfred Hospital in Australia. Their research spans multiple fields within medicine, particularly focusing on molecular biology and neurological disorders. They have contributed extensively to the study of neurodegenerative diseases, with significant work in Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

The scientist's research primarily covers these main fields of study:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, their subfields of expertise include:

  • Molecular Biology
  • Neurology
  • Genetics
  • Physiology
  • Oncology

Their main research topics encompass:

  • Alzheimer's disease research and treatments
  • Amyotrophic Lateral Sclerosis Research
  • Parkinson's Disease Mechanisms and Treatments
  • Cutaneous Melanoma Detection and Management
  • Prion Diseases and Protein Misfolding
  • Neurogenetic and Muscular Disorders Research
  • Genetic Neurodegenerative Diseases

Catriona McLean has coauthored many publications with researchers such as Colin L. Masters, Blaine R. Roberts, Bernardino Ghetti, Victoria Mar, and Paul S. Donnelly. Their work is frequently published in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Communicable Diseases Intelligence
  • Pathology
  • Australasian Journal of Dermatology

Examples of their recent papers include:

  • TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS (2020), published in Cell
  • cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas (2020), published in Acta Neuropathologica
  • Transcriptional signature in microglia associated with Aβ plaque phagocytosis (2021), published in Nature Communications
  • Characterization of brain-derived extracellular vesicle lipids in Alzheimer's disease (2021), published in Journal of Extracellular Vesicles
  • Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis (2021), published in Cell Death and Differentiation

Best Publications

  • Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.

    Catriona A. McLean;Robert A. Cherny;Fiona W. Fraser;Stephanie J. Fuller

  • Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

    Robert A Cherny;Craig S Atwood;Michel E Xilinas;Danielle N Gray

  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

    Fiona M. Blows;Kristy E. Driver;Marjanka K. Schmidt;Annegien Broeks

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

    James A. Duce;Andrew Tsatsanis;Michael A. Cater;Simon A. James

  • Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women

    Leila Dorling;Sara Carvalho;Jamie Allen

  • A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation.

    Alexandra Grubman;Alexandra Grubman;Alexandra Grubman;Gabriel Chew;John F Ouyang;Guizhi Sun;Guizhi Sun;Guizhi Sun

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Increased expression of the amyloid precursor β‐secretase in Alzheimer's disease

    R. M. Damian Holsinger;Catriona A. McLean;Konrad Beyreuther;Colin L. Masters

  • Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

    Peng Lei;Scott Ayton;David I Finkelstein;Loredana Spoerri

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Aqueous Dissolution of Alzheimer's Disease Aβ Amyloid Deposits by Biometal Depletion *

    Robert A. Cherny;Robert A. Cherny;Jacinta T. Legg;Jacinta T. Legg;Catriona A. McLean;Catriona A. McLean;David P. Fairlie

  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    Vivianna M. Van Deerlin;Patrick M A Sleiman;Maria Martinez-Lage;Maria Martinez-Lage;Alice Chen-Plotkin

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

    Gabor G. Kovacs;Isidro Ferrer;Lea T. Grinberg;Lea T. Grinberg;Irina Alafuzoff

  • Cerebral radiation necrosis: incidence, outcomes, and risk factors with emphasis on radiation parameters and chemotherapy.

    Jeremy D Ruben;Michael Dally;Michael John Bailey;Robin Smith

  • Genome-wide association studies identify four ER negative-specific breast cancer risk loci

    Montserrat Garcia-Closas;Fergus J. Couch;Sara Lindstrom;Kyriaki Michailidou

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Colin L. Masters
Colin L. Masters University of Melbourne
Melissa C. Southey
Melissa C. Southey Monash University
John L. Hopper
John L. Hopper University of Melbourne
Barbara Burwinkel
Barbara Burwinkel Heidelberg University
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Montserrat Garcia-Closas
Montserrat Garcia-Closas National Institutes of Health

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