Anthony Bretscher

Research.com Recognitions

• 2018 - Fellow of the American Academy of Arts and Sciences
• 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Global Mapping of the Yeast Genetic Interaction Network

  Amy Hin Yan Tong;Guillaume Lesage;Gary D. Bader;Huiming Ding

  2580
  Citations

• ERM proteins and merlin: integrators at the cell cortex

  Anthony Bretscher;Kevin Edwards;Richard G. Fehon

  1707
  Citations

• Organizing the cell cortex: the role of ERM proteins

  Richard G. Fehon;Andrea I. McClatchey;Anthony Bretscher

  1364
  Citations

• Role of Formins in Actin Assembly: Nucleation and Barbed-End Association

  David Pruyne;Marie Evangelista;Changsong Yang;Erfei Bi

  945
  Citations

• Polarization of cell growth in yeast.

  D. Pruyne;A. Bretscher

  883
  Citations

• Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family

  David Reczek;Mark Berryman;Anthony Bretscher

  850
  Citations

• A kinase-regulated PDZ-domain interaction controls endocytic sorting of the β2-adrenergic receptor

  Tracy T. Cao;Heather W. Deacon;David Reczek;Anthony Bretscher

  804
  Citations

• Structure of the ERM Protein Moesin Reveals the FERM Domain Fold Masked by an Extended Actin Binding Tail Domain

  Matthew A. Pearson;David Reczek;Anthony Bretscher;P.Andrew Karplus;P.Andrew Karplus

  733
  Citations

• The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane

  Athar H. Chishti;Anthony C. Kim;Shirin M. Marfatia;Mohini Lutchman

  671
  Citations

• Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states

  David Pruyne;Anthony Bretscher

  621
  Citations

• Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast

  Marie Evangelista;David Pruyne;David C Amberg;Charles Boone;Charles Boone

  619
  Citations

• Synergism between morphogenetic mutants of Myxococcus xanthus

  David C. Hagen;Anthony P. Bretscher;Dale Kaiser

  595
  Citations

• Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site.

  R Gary;A Bretscher

  593
  Citations

• Villin is a major protein of the microvillus cystoskeleton which binds both G and F actin in a calcium-dependent manner

  Anthony Bretscher;Klaus Weber

  591
  Citations

• Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells

  Mark Berryman;Zsofia Franck;Anthony Bretscher

  590
  Citations

• An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the Cytoskeleton

  Douglas B. Short;Kevin W. Trotter;David Reczek;Silvia M. Kreda

  577
  Citations

• Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.

  A Bretscher

  540
  Citations

• ERM-Merlin and EBP50 protein families in plasma membrane organization and function.

  Anthony Bretscher;David Chambers;Rachel Nguyen;David Reczek

  526
  Citations

• Mechanisms of polarized growth and organelle segregation in yeast.

  David Pruyne;Aster Legesse-Miller;Lina Gao;Yuqing Dong

  524
  Citations

• Regulation of cortical structure by the ezrin-radixin-moesin protein family.

  Anthony Bretscher

  519
  Citations