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Biology and Biochemistry

D-Index
54
Citations
12133
World Ranking
15517
National Ranking
6476

Overview

Ferruccio Galbiati is affiliated with the University of Pittsburgh in the United States. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a focus on several related subfields such as Cell Biology, Molecular Biology, Physiology, Cancer Research, and Oncology.

Their recent work includes several publications exploring cellular senescence, cancer biology, and molecular signaling pathways. Notable papers authored by Galbiati include:

  • Caveolin-1, a master regulator of cellular senescence (2020) published in Cancer and Metastasis Reviews
  • Impaired Cdc20 signaling promotes senescence in normal cells and apoptosis in non-small cell lung cancer cells (2022) published in Journal of Biological Chemistry
  • Cell autonomous angiotensin II signaling controls the pleiotropic functions of oncogenic K-Ras (2020) published in Journal of Biological Chemistry
  • Purinergic signaling promotes premature senescence (2024) published in Journal of Biological Chemistry

The research topics covered in these publications reflect diverse areas such as Caveolin-1 and cellular processes, erythrocyte function and pathophysiology, microRNA in disease regulation, microtubule and mitosis dynamics, cancer-related molecular pathways, DNA repair mechanisms, and mechanisms of cancer metastasis.

Galbiati has collaborated extensively with several co-authors. Frequent collaborators include Daniela Volonté, Morgan Sedorovitz, Victoria E. Cespedes, Maria Beecher, and Cory J. Benson.

Their work is often published in venues such as the Journal of Biological Chemistry, which has featured three of their papers, and Cancer and Metastasis Reviews, which has published one of their significant articles.

Best Publications

  • Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy.

    Carlo Minetti;Federica Sotgia;Claudio Bruno;Claudio Bruno;Paolo Scartezzini

  • Emerging Themes in Lipid Rafts and Caveolae

    Ferruccio Galbiati;Babak Razani;Michael P. Lisanti

  • Cell-type and Tissue-specific Expression of Caveolin-2 CAVEOLINS 1 AND 2 CO-LOCALIZE AND FORM A STABLE HETERO-OLIGOMERIC COMPLEX IN VIVO

    Philipp E. Scherer;Renée Y. Lewis;Daniela Volonté;Jeffrey A. Engelman

  • Targeted downregulation of caveolin‐1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

    Ferruccio Galbiati;Daniela Volonté;Jeffrey A. Engelman;Genichi Watanabe

  • Caveolin-3 Null Mice Show a Loss of Caveolae, Changes in the Microdomain Distribution of the Dystrophin-Glycoprotein Complex, and T-tubule Abnormalities

    Ferruccio Galbiati;Jeffrey A. Engelman;Daniela Volonte;Xiao Lan Zhang

  • Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.

    Hyangkyu Lee;Daniela Volonte;Ferruccio Galbiati;Puneeth Iyengar

  • Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.

    Ferruccio Galbiati;Daniela Volonte;Jun Liu;Franco Capozza

  • Cellular Stress Induces the Tyrosine Phosphorylation of Caveolin-1 (Tyr14) via Activation of p38 Mitogen-activated Protein Kinase and c-Src kinase: EVIDENCE FOR CAVEOLAE, THE ACTIN CYTOSKELETON, AND FOCAL ADHESIONS AS MECHANICAL SENSORS OF OSMOTIC STRESS *

    Daniela Volonté;Ferruccio Galbiati;Richard G. Pestell;Michael P. Lisanti

  • Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe.

    Daniela Volonté;Ferruccio Galbiati;Shengwen Li;Kazutoshi Nishiyama

  • Expression of caveolin -1 induces premature cellular senescence in primary cultures of murine fibroblasts

    Daniela Volonte;Kun Zhang;Michael P. Lisanti;Ferruccio Galbiati

  • Expression of Caveolin-1 Is Required for the Transport of Caveolin-2 to the Plasma Membrane RETENTION OF CAVEOLIN-2 AT THE LEVEL OF THE GOLGI COMPLEX

    Isabella Parolini;Isabella Parolini;Massimo Sargiacomo;Ferruccio Galbiati;Giovanni Rizzo

  • Caveolin-1 Expression Inhibits Wnt/β-Catenin/Lef-1 Signaling by Recruiting β-Catenin to Caveolae Membrane Domains

    Ferruccio Galbiati;Daniela Volonte;Anthony M.C. Brown;Anthony M.C. Brown;David E. Weinstein

  • Molecular Genetics of the Caveolin Gene Family: Implications for Human Cancers, Diabetes, Alzheimer Disease, and Muscular Dystrophy

    Jeffrey A. Engelman;XiaoLan Zhang;Ferruccio Galbiati;Daniela Volonté

  • Crowded little caves: structure and function of caveolae

    Amnon Schlegel;Daniela Volonté;Jeffrey A. Engelman;Ferruccio Galbiati

  • Affinity-purification and characterization of caveolins from the brain: differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types.

    Tsuneya Ikezu;Hideho Ueda;Bruce D Trapp;Kazutoshi Nishiyama

  • Caveolae and caveolin-3 in muscular dystrophy.

    Ferruccio Galbiati;Babak Razani;Michael P Lisanti

  • Caveolinopathies: mutations in caveolin-3 cause four distinct autosomal dominant muscle diseases.

    Scott Eric Woodman;F. Sotgia;F. Galbiati;C. Minetti

  • Upregulation of caveolin-1 and caveolae organelles in Taxol-resistant A549 cells

    Chia Ping Huang Yang;Ferruccio Galbiati;Daniela Volonté;Susan Band Horwitz

  • Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons : caveolin-2 is up-regulated in response to cell injury

    Ferruccio Galbiati;Daniela Volonté;Orlando Gil;George Zanazzi

  • EVIDENCE FOR CAVEOLAE, THE ACTIN CYTOSKELETON, AND FOCAL ADHESIONS AS MECHANICAL SENSORS OF OSMOTIC STRESS*

    Daniela Volonte;Ferruccio Galbiati;Michael P. Lisanti

Frequent Co-Authors

Michael P. Lisanti
Michael P. Lisanti University of Salford
Richard G. Pestell
Richard G. Pestell The Wistar Institute
Philipp E. Scherer
Philipp E. Scherer The University of Texas Southwestern Medical Center
Carlo Minetti
Carlo Minetti University of Genoa
Federica Sotgia
Federica Sotgia University of Salford
Claudio Bruno
Claudio Bruno Istituto Giannina Gaslini
Massimo Sargiacomo
Massimo Sargiacomo Istituto Superiore di Sanità
Anthony M. C. Brown
Anthony M. C. Brown Cornell University
Cesare Peschle
Cesare Peschle Istituto Superiore di Sanità
Tsuneya Ikezu
Tsuneya Ikezu Boston University

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