World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
68
Citations
13735
World Ranking
1532
National Ranking
31

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • DNA

Cesare Peschle focuses on Cell biology, Cellular differentiation, Haematopoiesis, Immunology and Molecular biology. His Cell biology study combines topics from a wide range of disciplines, such as Cell culture, Receptor, Erythropoietin and Apoptosis. His biological study spans a wide range of topics, including Acute promyelocytic leukemia and Erythroblast.

His Haematopoiesis research is multidisciplinary, incorporating elements of Internal medicine and Endocrinology. He has researched Immunology in several fields, including CD34, Stem cell and Kinase insert domain receptor. Cesare Peschle interconnects Cord blood, Progenitor cell, Transcription factor, Biochemistry and Regulation of gene expression in the investigation of issues within Molecular biology.

His most cited work include:

  • The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. (806 citations)
  • MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation (705 citations)
  • MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation (705 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cell biology, Haematopoiesis, Molecular biology, Internal medicine and Progenitor cell. His work carried out in the field of Cell biology brings together such families of science as Cell culture, Cell growth, Apoptosis, Immunology and Receptor. As a part of the same scientific family, Cesare Peschle mostly works in the field of Haematopoiesis, focusing on Cellular differentiation and, on occasion, Acute promyelocytic leukemia and Erythroblast.

The Molecular biology study which covers microRNA that intersects with Northern blot. Cesare Peschle works mostly in the field of Internal medicine, limiting it down to concerns involving Endocrinology and, occasionally, Spleen. His Progenitor cell study is related to the wider topic of Stem cell.

He most often published in these fields:

  • Cell biology (56.50%)
  • Haematopoiesis (53.66%)
  • Molecular biology (49.19%)

What were the highlights of his more recent work (between 2003-2019)?

  • Cell biology (56.50%)
  • Progenitor cell (36.59%)
  • Haematopoiesis (53.66%)

In recent papers he was focusing on the following fields of study:

Cesare Peschle spends much of his time researching Cell biology, Progenitor cell, Haematopoiesis, microRNA and Molecular biology. His research integrates issues of Receptor, Apoptosis, Death domain and Fas receptor in his study of Cell biology. His Progenitor cell research incorporates themes from Cell culture and Clinical uses of mesenchymal stem cells, Adult stem cell.

The study incorporates disciplines such as Regulation of gene expression, Transcription factor, Gene expression and Autocrine signalling in addition to Haematopoiesis. His studies deal with areas such as Gene silencing, Prostate cancer and Northern blot as well as microRNA. His research in Molecular biology intersects with topics in Stem cell factor, Cell growth and Cellular differentiation.

Between 2003 and 2019, his most popular works were:

  • The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. (806 citations)
  • MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation (705 citations)
  • MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation (705 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • DNA

His primary areas of study are Cell biology, microRNA, Immunology, Cancer research and Gene silencing. Cesare Peschle works in the field of Cell biology, namely Signal transduction. In his research on the topic of Signal transduction, Cell culture is strongly related with Apoptosis.

His Cell culture study combines topics in areas such as Progenitor cell, Molecular biology and Cellular differentiation. He combines subjects such as Cancer, Stem cell factor, Cell growth and Transfection with his study of microRNA. His Immunology research is multidisciplinary, relying on both Retinoic acid, Transplantation and Decoy receptors.

Best Publications

  • MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation

    Nadia Felli;Laura Fontana;Elvira Pelosi;Rosanna Botta

  • The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

    Francesco Grignani;Pier Francesco Ferrucci;Ugo Testa;Giampaolo Talamo

  • KDR receptor: a key marker defining hematopoietic stem cells.

    B. L. Ziegler;M. Valtieri;M. Valtieri;G. Almeida Porada;R. De Maria;R. De Maria

  • MicroRNAs 17-5p–20a–106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation

    Laura Fontana;Elvira Pelosi;Paolo Greco;Serena Racanicchi

  • Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1

    Ruggero De Maria;Ruggero De Maria;Ann Zeuner;Ann Zeuner;Adriana Eramo;Cristina Domenichelli

  • High-Efficiency Gene Transfer and Selection of Human Hematopoietic Progenitor Cells with a Hybrid EBV/Retroviral Vector Expressing the Green Fluorescence Protein

    Francesco Grignani;Todd Kinsella;Amedea Mencarelli;Mauro Valtieri

  • Elevated expression of IL-3Rα in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis

    Ugo Testa;Ugo Testa;Ugo Testa;Roberta Riccioni;Roberta Riccioni;Roberta Riccioni;Stefania Militi;Stefania Militi;Stefania Militi;Eliana Coccia;Eliana Coccia;Eliana Coccia

  • Human embryonic hemopoiesis. Kinetics of progenitors and precursors underlying the yolk sac----liver transition.

    G Migliaccio;A R Migliaccio;S Petti;F Mavilio

  • Identification of the hemangioblast in postnatal life.

    Elvira Pelosi;Mauro Valtieri;Simona Coppola;Rosanna Botta

  • Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis

    R. De Maria;R. De Maria;R. De Maria;U. Testa;U. Testa;U. Testa;L. Luchetti;L. Luchetti;L. Luchetti;A. Zeuner;A. Zeuner;A. Zeuner

  • Expression of Caveolin-1 Is Required for the Transport of Caveolin-2 to the Plasma Membrane RETENTION OF CAVEOLIN-2 AT THE LEVEL OF THE GOLGI COMPLEX

    Isabella Parolini;Isabella Parolini;Massimo Sargiacomo;Ferruccio Galbiati;Giovanni Rizzo

  • Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer.

    G Scambia;U Testa;P Benedetti Panici;E Foti

  • Signal transduction and glycophosphatidylinositol-linked proteins (lyn, lck, CD4, CD45, G proteins, and CD55) selectively localize in Triton-insoluble plasma membrane domains of human leukemic cell lines and normal granulocytes.

    I Parolini;M Sargiacomo;MP Lisanti;C Peschle

  • Autocrine-paracrine VEGF loops potentiate the maturation of megakaryocytic precursors through Flt1 receptor.

    Ida Casella;Tiziana Feccia;Tiziana Feccia;Cristiana Chelucci;Cristiana Chelucci;Paola Samoggia;Paola Samoggia

  • Overexpression of the zinc finger protein MZF1 inhibits hematopoietic development from embryonic stem cells: correlation with negative regulation of CD34 and c-myb promoter activity.

    D Perrotti;P Melotti;T Skorski;I Casella

  • IL-4 protects tumor cells from anti-CD95 and chemotherapeutic agents via up-regulation of antiapoptotic proteins.

    Concetta Conticello;Francesca Pedini;Ann Zeuner;Mariella Patti

  • Molecular mechanisms of human hemoglobin switching: selective undermethylation and expression of globin genes in embryonic, fetal, and adult erythroblasts.

    F Mavilio;A Giampaolo;A Carè;G Migliaccio

  • Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis.

    C Labbaye;M Valtieri;T Barberi;E Meccia

  • Transforming growth factor-beta potentiates vitamin D3-induced terminal monocytic differentiation of human leukemic cell lines.

    U Testa;R Masciulli;E Tritarelli;R Pustorino

  • The transferrin receptor.

    Testa U;Pelosi E;Peschle C

Frequent Co-Authors

Ugo Testa
Ugo Testa Istituto Superiore di Sanità
Mauro Valtieri
Mauro Valtieri Istituto Superiore di Sanità
Gianluigi Condorelli
Gianluigi Condorelli Humanitas University
Giovanni Migliaccio
Giovanni Migliaccio University of Washington
Anna Rita Migliaccio
Anna Rita Migliaccio University of Bologna
Ruggero De Maria
Ruggero De Maria Catholic University of the Sacred Heart
Carlo M. Croce
Carlo M. Croce The Ohio State University
Fulvio Mavilio
Fulvio Mavilio University of Modena and Reggio Emilia
Sergio Ottolenghi
Sergio Ottolenghi University of Milano-Bicocca
Gianni Marone
Gianni Marone University of Naples Federico II

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