What is he best known for?
The fields of study he is best known for:
- Enzyme
- Cancer
- Biochemistry
Philippe G. Frank focuses on Cell biology, Caveolae, Internal medicine, Endocrinology and Reverse Warburg effect.
The concepts of his Cell biology study are interwoven with issues in Cell, Endocytosis, Albumin and Ligand.
His Caveolae research integrates issues from Transcytosis, Caveolin 1, In vivo and Blood vessel.
In his work, Tumor progression and Metabolism is strongly intertwined with Cancer research, which is a subfield of Internal medicine.
His work carried out in the field of Endocrinology brings together such families of science as CD36 and Atheroma.
While the research belongs to areas of Reverse Warburg effect, Philippe G. Frank spends his time largely on the problem of Stromal cell, intersecting his research to questions surrounding Cancer-Associated Fibroblasts.
His most cited work include:
- The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma (798 citations)
- Caveolin-1-deficient Mice Are Lean, Resistant to Diet-induced Obesity, and Show Hypertriglyceridemia with Adipocyte Abnormalities (467 citations)
- Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism (393 citations)
What are the main themes of his work throughout his whole career to date?
Cell biology, Caveolae, Caveolin 1, Cholesterol and Internal medicine are his primary areas of study.
His studies examine the connections between Cell biology and genetics, as well as such issues in Cell, with regards to Cell growth.
Many of his research projects under Caveolae are closely connected to Cellular differentiation with Cellular differentiation, tying the diverse disciplines of science together.
His Caveolin 1 study combines topics in areas such as Apoptosis, Sphingolipid, Signal transduction and Homeostasis.
His work in Cholesterol addresses subjects such as Efflux, which are connected to disciplines such as Phospholipid efflux.
His Internal medicine research includes themes of Endocrinology, Oncology and Cancer research.
He most often published in these fields:
- Cell biology (39.00%)
- Caveolae (36.00%)
- Caveolin 1 (37.00%)
What were the highlights of his more recent work (between 2012-2021)?
- Cancer research (23.00%)
- Cancer (14.00%)
- Cholesterol (25.00%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Cancer research, Cancer, Cholesterol, Breast cancer and Caveolin 1.
The Cancer research study combines topics in areas such as Cell migration, Cancer cell, Scavenger receptor, Signal transduction and Docetaxel.
His Cancer research is included under the broader classification of Internal medicine.
Cholesterol is the subject of his research, which falls under Biochemistry.
His research integrates issues of Inflammation and Caveolae, Caveolin in his study of Caveolin 1.
Philippe G. Frank has researched Caveolae in several fields, including Transcytosis, Endothelium and Lipoprotein.
Between 2012 and 2021, his most popular works were:
- Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development (82 citations)
- SR-BI: Linking Cholesterol and Lipoprotein Metabolism with Breast and Prostate Cancer. (41 citations)
- Endothelial caveolin-1 plays a major role in the development of atherosclerosis (37 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Cancer
- Biochemistry
Philippe G. Frank mostly deals with Cancer research, Signal transduction, Cancer cell, Cell biology and Scavenger receptor.
The study incorporates disciplines such as MAPK/ERK pathway, Biochemistry, Foam cell, RHOA and Metastasis Suppressor Gene in addition to Cancer research.
He combines subjects such as Lipid metabolism, Internal medicine, Reverse cholesterol transport and Phosphodiesterase with his study of Signal transduction.
His studies in Cancer cell integrate themes in fields like Cell migration, Extracellular, Metastasis, Intracellular and Breast cancer.
In general Cell biology study, his work on Caveolin 1 and Caveolae often relates to the realm of Vascular endothelial growth factor B, thereby connecting several areas of interest.
His Scavenger receptor study integrates concerns from other disciplines, such as Cancer, Cell signaling, Protein kinase B, Protein kinase A and PI3K/AKT/mTOR pathway.
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