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Isabelle Dugail

Isabelle Dugail

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
25367
World Ranking
18525
National Ranking
848

Overview

Isabelle Dugail is a researcher affiliated with Inserm in France, with a focus on medicine, biochemistry, genetics, and molecular biology. Their research spans several subfields including physiology, epidemiology, molecular biology, cancer research, and cardiology and cardiovascular medicine. The scientist's work addresses key topics such as adipokines, inflammation, and metabolic diseases; adipose tissue and metabolism; extracellular vesicles in disease; microRNA in disease regulation; cardiovascular disease and adiposity; autophagy in disease and therapy; as well as diet and metabolism studies.

Dugail has contributed to a number of scientific publications, with notable recent papers including:

  • Lipidomic analysis of adipose-derived extracellular vesicles reveals specific EV lipid sorting informative of the obesity metabolic state (2023, Cell Reports)
  • High prevalence for obesity in severe COVID-19: Possible links and perspectives towards patient stratification (2020, Biochimie)
  • Importance of the Microenvironment and Mechanosensing in Adipose Tissue Biology (2022, Cells)
  • Autophagy inhibition blunts PDGFRA adipose progenitors' cell-autonomous fibrogenic response to high-fat diet (2020, Autophagy)
  • Increased Weight Gain and Insulin Resistance in HF-Fed PLTP Deficient Mice Is Related to Altered Inflammatory Response and Plasma Transport of Gut-Derived LPS (2022, International Journal of Molecular Sciences)

The researcher has frequently published in several venues, including:

  • Diabetes
  • Biochimie
  • International Journal of Molecular Sciences
  • Cell Reports
  • Cells

Dugail often collaborates with coauthors such as Karine Clément, Simon Lecoutre, Soazig Le Lay, Camille Gamblin, and Christine Rouault. These frequent coauthor relationships indicate ongoing collaborative efforts in their research domains.

The main fields of study for this scientist include medicine and biochemistry, genetics, and molecular biology, with a strong emphasis on physiological and molecular pathways, disease epidemiology, and cardiovascular and cancer-related investigations.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose

    Marc Foretz;Corinne Pacot;Isabelle Dugail;Patricia Lemarchand

  • Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy.

    C. A. Kim;Marc Delépine;Emilie Boutet;Haquima El Mourabit

  • Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat.

    S Hallakou;L Doaré;F Foufelle;M Kergoat

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Cholesterol, a Cell Size-dependent Signal That Regulates Glucose Metabolism and Gene Expression in Adipocytes

    Soazig Le Lay;Stéphane Krief;Céline Farnier;Isabelle Lefrère

  • Insulin and Sterol-regulatory Element-binding Protein-1c (SREBP-1C) Regulation of Gene Expression in 3T3-L1 Adipocytes IDENTIFICATION OF CCAAT/ENHANCER-BINDING PROTEIN β AS AN SREBP-1C TARGET

    Soazig Le Lay;Isabelle Lefrère;Christian Trautwein;Isabelle Dugail

  • Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis.

    Soazig Le Lay;Eric Hajduch;Margaret R. Lindsay;Xavier Le Lièpvre

  • ADD-1/SREBP-1 is a major determinant of tissue differential lipogenic capacity in mammalian and avian species.

    Florence Gondret;Pascal Ferré;Isabelle Dugail

  • Decreased resistin expression in mice with different sensitivities to a high-fat diet.

    Soazig Le Lay;Jérémie Boucher;Astrid Rey;Isabelle Castan-Laurell

  • Obesity-related Overexpression of Fatty-acid Synthase Gene in Adipose Tissue Involves Sterol Regulatory Element-binding Protein Transcription Factors

    Muriel Boizard;Xavier Le Liepvre;Patricia Lemarchand;Fabienne Foufelle

  • Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes

    Céline Dubuquoy;Céline Robichon;Céline Robichon;Céline Robichon;Françoise Lasnier;Françoise Lasnier;Clotilde Langlois;Clotilde Langlois

  • Cavin proteins: New players in the caveolae field

    Nolwenn Briand;Isabelle Dugail;Isabelle Dugail;Isabelle Dugail;Soazig Le Lay;Soazig Le Lay;Soazig Le Lay

  • Plasma membrane subdomain compartmentalization contributes to distinct mechanisms of ceramide action on insulin signaling.

    Cédric M. Blouin;Cécilia Prado;Karen K. Takane;Françoise Lasnier

  • Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects.

    Cédric M. Blouin;Soazig Le Lay;Anita Eberl;Harald C Köfeler

  • Targeting of PKCzeta and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide.

    Eric Hajduch;Eric Hajduch;Sophie Turban;Xavier Le Liepvre;Xavier Le Liepvre;Soazig Le Lay;Soazig Le Lay

  • In Vitro Suppression of the Lipogenic Pathway by the Nonnucleoside Reverse Transcriptase Inhibitor Efavirenz in 3T3 and Human Preadipocytes or Adipocytes

    Khadija El Hadri;Martine Glorian;Christelle Monsempes;Marie-Noëlle Dieudonné

  • Circulating phospholipid profiling identifies portal contribution to NASH signature in obesity

    Kavya Anjani;Kavya Anjani;Kavya Anjani;Marie Lhomme;Nataliya Sokolovska;Nataliya Sokolovska;Nataliya Sokolovska;Christine Poitou;Christine Poitou;Christine Poitou

Frequent Co-Authors

Pascal Ferré
Pascal Ferré Sorbonne University
Eric Hajduch
Eric Hajduch European Association for the Study of Diabetes
Karine Clément
Karine Clément Sorbonne University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Fabienne Foufelle
Fabienne Foufelle Sorbonne University
Sergio Lavandero
Sergio Lavandero University of Chile
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Catherine Postic
Catherine Postic Institut Cochin
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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