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Catherine Postic

Catherine Postic

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
18351
World Ranking
14782
National Ranking
576

Overview

Catherine Postic is affiliated with the Institut Cochin in France. Their research primarily spans several fields within medicine and biochemistry, genetics, and molecular biology, with a significant focus on subfields such as epidemiology, molecular biology, physiology, surgery, and endocrinology, diabetes, and metabolism.

The scientist's work addresses multiple main topics, including:

  • Liver Disease Diagnosis and Treatment
  • Diet, Metabolism, and Disease
  • Lipid Metabolism and Biosynthesis
  • Adipose Tissue and Metabolism
  • Cholesterol and Lipid Metabolism
  • Diet and Metabolism Studies
  • Pancreatic Function and Diabetes

Catherine Postic has authored several recent papers, highlighting advances in understanding nonalcoholic fatty liver disease (NAFLD) and related metabolic processes. Some of these key publications include:

  • "New targets for NAFLD," published in 2021 in JHEP Reports
  • "Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity," published in 2020 in Scientific Reports
  • "ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity," published in 2022 in Cell Reports
  • "The role of ChREBP in carbohydrate sensing and NAFLD development," published in 2023 in Nature Reviews Endocrinology
  • "Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target," published in 2021 in Gut

The publication venues where Catherine Postic frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • JHEP Reports
  • Scientific Reports
  • Cell Reports
  • Journal of Hepatology

Collaboration forms an important aspect of their research output. Frequent co-authors working with Catherine Postic are:

  • Hervé Guillou
  • Marion Régnier
  • Fadila Benhamed
  • Arnaud Polizzi
  • Alexandra Montagner

Best Publications

  • Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

    M.Dodson Michael;Rohit N. Kulkarni;Catherine Postic;Steven F. Previs

  • Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase.

    C. Postic;M. Shiota;K. D. Niswender;T. L. Jetton

  • Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes

    R N Kulkarni;J C Brüning;J N Winnay;C Postic

  • Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

    Catherine Postic;Jean Girard

  • Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

    Lesley Hoyles;José-Manuel Fernández-Real;Massimo Federici;Matteo Serino;Matteo Serino

  • Role of the liver in the control of carbohydrate and lipid homeostasis

    C Postic;R Dentin;J Girard

  • Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice

    Renaud Dentin;Fadila Benhamed;Isabelle Hainault;Véronique Fauveau

  • Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression.

    Renaud Dentin;Jean-Paul Pégorier;Fadila Benhamed;Fabienne Foufelle

  • Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver.

    Renaud Dentin;Jean Girard;Catherine Postic

  • DNA excision in liver by an albumin‐Cre transgene occurs progressively with age

    Catherine Postic;Mark A. Magnuson

  • The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

    Fadila Benhamed;Pierre-Damien Denechaud;Maud Lemoine;Céline Robichon

  • Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation

    Renaud Dentin;Fadila Benhamed;Jean-Paul Pégorier;Fabienne Foufelle

  • Brain glucagon-like peptide–1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage

    Claude Knauf;Patrice D. Cani;Christophe Perrin;Miguel A. Iglesias

  • The role of the lipogenic pathway in the development of hepatic steatosis.

    C. Postic;C. Postic;J. Girard;J. Girard

  • Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

    Julien Bricambert;Jonatan Miranda;Fadila Benhamed;Jean Girard

  • ChREBP, a transcriptional regulator of glucose and lipid metabolism.

    Catherine Postic;Renaud Dentin;Pierre-Damien Denechaud;Jean Girard

  • Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism.

    Pengxiang She;Masakazu Shiota;Kathy D. Shelton;Roger Chalkley

  • Hepatocyte-Specific Mutation Establishes Retinoid X Receptor α as a Heterodimeric Integrator of Multiple Physiological Processes in the Liver

    Yu Jui Yvonne Wan;Dahsing An;Yan Cai;Joyce J. Repa

  • ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver

    Pierre-Damien Denechaud;Pascale Bossard;Jean-Marc A. Lobaccaro;Lesley Millatt

  • Novel insights into ChREBP regulation and function

    Gaëlle Filhoulaud;Gaëlle Filhoulaud;Gaëlle Filhoulaud;Sandra Guilmeau;Sandra Guilmeau;Sandra Guilmeau;Renaud Dentin;Renaud Dentin;Renaud Dentin;Jean Girard;Jean Girard;Jean Girard

Frequent Co-Authors

Hervé Guillou
Hervé Guillou INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Walter Wahli
Walter Wahli University of Lausanne
Mark A. Magnuson
Mark A. Magnuson Vanderbilt University
Fabienne Foufelle
Fabienne Foufelle Sorbonne University
Pascal Ferré
Pascal Ferré Sorbonne University
Jean-Philippe Girard
Jean-Philippe Girard Federal University of Toulouse Midi-Pyrénées
Bart Staels
Bart Staels University of Lille

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