World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
14396
World Ranking
16488
National Ranking
86

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Leiv Sigve Håvarstein focuses on Bacteriocin, Biochemistry, Peptide sequence, Amino acid and Genetics. His study in Bacteriocin is interdisciplinary in nature, drawing from both Open reading frame, Peptide and Lactic acid. His Biochemistry research includes themes of Lantibiotics, Microbiology and Bacteria.

His research investigates the connection with Microbiology and areas like Nucleic acid sequence which intersect with concerns in Antibacterial agent. Leiv Sigve Håvarstein is studying Edman degradation, which is a component of Peptide sequence. His works in Gene, DNA Transformation Competence, Transformation, Histidine kinase and Operon are all subjects of inquiry into Genetics.

His most cited work include:

  • Biosynthesis of bacteriocins in lactic acid bacteria (697 citations)
  • An unmodified heptadecapeptide pheromone induces competence for genetic transformation in Streptococcus pneumoniae (632 citations)
  • A family of bacteriocin ABC transporters carry out proteolytic processing of their substrates concomitant with export (498 citations)

What are the main themes of his work throughout his whole career to date?

Leiv Sigve Håvarstein mainly investigates Microbiology, Biochemistry, Streptococcus pneumoniae, Gene and Genetics. His research in Microbiology focuses on subjects like Lysis, which are connected to Naked DNA. He regularly links together related areas like Bacteriocin in his Biochemistry studies.

His Bacteriocin research includes elements of Consensus sequence, Edman degradation and Peptide. His Streptococcus pneumoniae research focuses on Mutant and how it connects with Transcription. Leiv Sigve Håvarstein works mostly in the field of Peptide sequence, limiting it down to topics relating to Nucleic acid sequence and, in certain cases, Antibacterial agent.

He most often published in these fields:

  • Microbiology (37.04%)
  • Biochemistry (33.33%)
  • Streptococcus pneumoniae (29.63%)

What were the highlights of his more recent work (between 2017-2021)?

  • Peptidoglycan (22.22%)
  • Cell biology (22.22%)
  • Cell division (14.81%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Peptidoglycan, Cell biology, Cell division, Bacterial cell structure and Cell. His research integrates issues of Streptococcus pneumoniae and Function in his study of Peptidoglycan. In the field of Microbiology and Bacteria Leiv Sigve Håvarstein studies Streptococcus pneumoniae.

His work carried out in the field of Cell biology brings together such families of science as Tyrosine, FtsZ and Site-directed mutagenesis. The study incorporates disciplines such as CRISPR interference and Gene in addition to Cell division. His Bacterial cell structure research is multidisciplinary, incorporating perspectives in Penicillin binding proteins and Immunoprecipitation.

Between 2017 and 2021, his most popular works were:

  • Class A PBPs have a distinct and unique role in the construction of the pneumococcal cell wall. (20 citations)
  • Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae. (20 citations)
  • Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae. (17 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Leiv Sigve Håvarstein spends much of his time researching Cell division, Peptidoglycan, Cell biology, CRISPR interference and Gene. His Peptidoglycan study is related to the wider topic of Biochemistry. His work on Operon, DNA ligase and Active site as part of general Biochemistry study is frequently connected to Glutamine amidotransferase, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

His biological study spans a wide range of topics, including Bacterial cell structure and Cell Cycle Protein. Leiv Sigve Håvarstein has researched CRISPR interference in several fields, including Mutation, Cell, Gene knockdown and Cell Cycle Gene. His Gene study is concerned with the larger field of Genetics.

Best Publications

  • Biosynthesis of bacteriocins in lactic acid bacteria

    Ingolf F. Nes;Dzung Bao Diep;Leiv Sigve Håvarstein;May Bente Brurberg

  • An unmodified heptadecapeptide pheromone induces competence for genetic transformation in Streptococcus pneumoniae

    Leiv Sigve Havarstein;Gowri Coomaraswamy;Donald A. Morrison

  • A family of bacteriocin ABC transporters carry out proteolytic processing of their substrates concomitant with export

    Leiv Sigve Havarstein;Dzung Bao Diep;Ingolf F. Nes

  • Biochemical and genetic characterization of enterocin P, a novel sec-dependent bacteriocin from Enterococcus faecium P13 with a broad antimicrobial spectrum.

    L M Cintas;P Casaus;L S Håvarstein;P E Hernández

  • Biochemical and genetic characterization of enterocin A from Enterococcus faecium, a new antilisterial bacteriocin in the pediocin family of bacteriocins.

    T Aymerich;H Holo;L S Håvarstein;M Hugas

  • Production of class II bacteriocins by lactic acid bacteria; an example of biological warfare and communication

    Vincent G H Eijsink;Lars Axelsson;Dzung B Diep;Leiv S Håvarstein

  • Regulation of competence for genetic transformation in Streptococcus pneumoniae by an auto-induced peptide pheromone and a two-component regulatory system.

    E. V. Pestova;L. S. Håvarstein;D. A. Morrison

  • A novel lactococcal bacteriocin whose activity depends on the complementary action of two peptides.

    J Nissen-Meyer;H Holo;L S Håvarstein;K Sletten

  • Characterization of the locus responsible for the bacteriocin production in Lactobacillus plantarum C11.

    D B Diep;L S Håvarstein;I F Nes

  • Natural genetic transformation: prevalence, mechanisms and function.

    Ola Johnsborg;Vegard Eldholm;Leiv Sigve Håvarstein

  • Enterocins L50A and L50B, Two Novel Bacteriocins from Enterococcus faecium L50, Are Related to Staphylococcal Hemolysins

    Luis M. Cintas;Pilar Casaus;Helge Holo;Pablo E. Hernandez

  • Biochemical and Genetic Evidence that Enterococcus faecium L50 Produces Enterocins L50A and L50B, the sec-Dependent Enterocin P, and a Novel Bacteriocin Secreted without an N-Terminal Extension Termed Enterocin Q

    Luis M. Cintas;Pilar Casaus;Carmen Herranz;Leiv Sigve Håvarstein

  • IDENTIFICATION OF THE STREPTOCOCCAL COMPETENCE-PHEROMONE RECEPTOR

    Leiv Sigve Håvarstein;Peter Gaustad;Ingolf F. Nes;Donald A. Morrison

  • Induction of natural competence in Streptococcus pneumoniae triggers lysis and DNA release from a subfraction of the cell population.

    Hilde Steinmoen;Eivind Knutsen;Leiv Sigve Håvarstein

  • Natural competence in the genus Streptococcus: evidence that streptococci can change pherotype by interspecies recombinational exchanges.

    Leiv Sigve Håvarstein;Regine Hakenbeck;Peter Gaustad

  • Evolution of Streptococcus pneumoniae and its close commensal relatives.

    Mogens Kilian;Knud Poulsen;Trinelise Blomqvist;Leiv S. Håvarstein

  • Cannibalism and fratricide: mechanisms and raisons d'être.

    Jean-Pierre Claverys;Leiv S. Håvarstein

  • Competence for genetic transformation in encapsulated strains of Streptococcus pneumoniae: two allelic variants of the peptide pheromone.

    Gianni Pozzi;L. Masala;Francesco Iannelli;R. Manganelli

  • The leader peptide of colicin V shares consensus sequences with leader peptides that are common among peptide bacteriocins produced by gram-positive bacteria.

    Leiv Sigve Håvarstein;Helge Holo;Ingolf F. Nes

  • Identification of DNA binding sites for ComE, a key regulator of natural competence in Streptococcus pneumoniae

    Ola Ween;Peter Gaustad;Leiv Sigve Håvarstein

Frequent Co-Authors

Ingolf F. Nes
Ingolf F. Nes Norwegian University of Life Sciences
Juan A. Hermoso
Juan A. Hermoso Spanish National Research Council
Dzung B. Diep
Dzung B. Diep Norwegian University of Life Sciences
Jean-Pierre Claverys
Jean-Pierre Claverys Paul Sabatier University
Waldemar Vollmer
Waldemar Vollmer Newcastle University
Jon Nissen-Meyer
Jon Nissen-Meyer University of Oslo
Mogens Kilian
Mogens Kilian Aarhus University
Pablo E. Hernández
Pablo E. Hernández Complutense University of Madrid
Donald A. Morrison
Donald A. Morrison University of Illinois at Chicago
Hervé Tettelin
Hervé Tettelin University of Maryland, Baltimore

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