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Eun-hye Joe

Eun-hye Joe

D-Index & Metrics

Neuroscience

D-Index
59
Citations
10200
World Ranking
4064
National Ranking
18

Overview

Eun-hye Joe is affiliated with Ajou University in South Korea and is an active researcher in the fields of neuroscience and medicine. Their work principally revolves around neurology, cellular and molecular neuroscience, developmental neuroscience, molecular biology, and immunology.

The scientist's research focus includes several key topics such as:

  • Neuroinflammation and neurodegeneration mechanisms
  • Nerve injury and regeneration
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroscience and neuropharmacology research
  • Parkinson's disease mechanisms and treatments
  • Anesthesia and neurotoxicity research
  • Tryptophan and brain disorders

Their recent publications cover various aspects of brain injury, repair, and neurodegenerative conditions. Selected papers include:

  • "Dying neurons conduct repair processes in the injured brain through osteopontin expression in cooperation with infiltrated blood monocytes," 2020, Glia
  • "Critical roles of astrocytic-CCL2-dependent monocyte infiltration in a DJ-1 knockout mouse model of delayed brain repair," 2020, Glia
  • "The dual role of c-src in cell-to-cell transmission of α-synuclein," 2020, EMBO Reports
  • "Peptide-mediated targeted delivery of SOX9 nanoparticles into astrocytes ameliorates ischemic brain injury," 2023, Nanoscale
  • "Small heterodimer partner (SHP) aggravates ER stress in Parkinson's disease-linked LRRK2 mutant astrocyte by regulating XBP1 SUMOylation," 2021, Journal of Biomedical Science

Frequent coauthors collaborating with Eun-hye Joe include Ilo Jou, Sang Myun Park, Hai-Jie Yang, Jiawei An, and Byung Gon Kim. These collaborations have supported research output primarily published in venues such as Glia, EMBO Reports, Molecular Brain, Experimental Neurobiology, and Zenodo (CERN European Organization for Nuclear Research).

Through consistent contributions to journals and interdisciplinary studies, Eun-hye Joe has engaged with advanced topics in brain repair mechanisms, neurodegenerative disease pathways, and targeted therapeutic delivery systems. Their research outputs demonstrate sustained involvement in examining the cellular and molecular underpinnings of neurological disorders and brain injury recovery processes.

Best Publications

  • Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia.

    Hee Young Kim;Eun Jung Park;Eun-hye Joe;Ilo Jou

  • 15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia.

    Eun Jung Park;Soo Young Park;Eun-hye Joe;Ilo Jou

  • Astrocytes induce hemeoxygenase-1 expression in microglia: a feasible mechanism for preventing excessive brain inflammation.

    Kyoung-Jin Min;Myung-soon Yang;Seung-Up Kim;Ilo Jou

  • Neuroprotective effects of human mesenchymal stem cells on dopaminergic neurons through anti-inflammatory action.

    You Joung Kim;Hyun Jung Park;Gwang Lee;Oh Young Bang

  • Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia

    Hankyoung Pyo;Ilo Jou;Soyoung Jung;Sumin Hong

  • Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures

    Eun Young Kim;Jae Young Koh;Yang Hee Kim;Seonghyang Sohn

  • Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo.

    Sang-H. Choi;Eun H. Joe;Seung U. Kim;Byung K. Jin

  • Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia

    Beomsue Kim;Myung Soon Yang;Dongjoo Choi;Jong Hyeon Kim

  • JAK-STAT Signaling Mediates Gangliosides-induced Inflammatory Responses in Brain Microglial Cells

    Ohn Soon Kim;Eun Jung Park;Eun-hye Joe;Ilo Jou

  • Thrombin Induces NO Release from Cultured Rat Microglia via Protein Kinase C, Mitogen-activated Protein Kinase, and NF-κB

    Jooyoung Ryu;Hankyoung Pyo;Ilo Jou;Eunhye Joe

  • Differential SUMOylation of LXRα and LXRβ Mediates Transrepression of STAT1 Inflammatory Signaling in IFN-γ-Stimulated Brain Astrocytes

    Jee Hoon Lee;Sang Myun Park;Ohn Soon Kim;Chang Seok Lee

  • Gangliosides Trigger Inflammatory Responses via TLR4 in Brain Glia

    Ilo Jou;Jee Hoon Lee;Soo Young Park;Hee Jung Yoon

  • Gangliosides Activate Cultured Rat Brain Microglia

    Hankyoung Pyo;Eun-hye Joe;Soyoung Jung;Soo Hwan Lee

  • Microglia Expressing Interleukin-13 Undergo Cell Death and Contribute to Neuronal Survival In Vivo

    Won Ho Shin;Da-Yong Lee;Keun Woo Park;Seung Up Kim

  • Astrocytes, Microglia, and Parkinson's Disease

    Eun-Hye Joe;Dong-Joo Choi;Jiawei An;Jin-Hwa Eun

  • Immune following suppression mesenchymal stem cell transplantation in the ischemic brain is mediated by TGF-β

    Seung-Wan Yoo;Da-Young Chang;Hye-Sun Lee;Gyu-Hee Kim

  • Interleukin-13 and -4 induce death of activated microglia.

    Myung-Soon Yang;Eun Jung Park;Seonghyang Sohn;Hyuk Jae Kwon

  • Resident microglia die and infiltrated neutrophils and monocytes become major inflammatory cells in lipopolysaccharide-injected brain.

    Kyung-Ae Ji;Myung-Soon Yang;Hey-Kyeong Jeong;Kyoung-Jin Min

  • Systemic LPS administration induces brain inflammation but not dopaminergic neuronal death in the substantia nigra

    Hey Kyeong Jeong;Ilo Jou;Eun hye Joe

  • Gangliosides activate microglia via protein kinase C and NADPH oxidase.

    Kyoung-Jin Min;Han-Kyung Pyo;Myung-Soon Yang;Kyung-Ae Ji

Frequent Co-Authors

Byoung Joo Gwag
Byoung Joo Gwag Yonsei University
Seung U. Kim
Seung U. Kim University of British Columbia
Oh Young Bang
Oh Young Bang Samsung Medical Center
Phil Hyu Lee
Phil Hyu Lee Yonsei University
Xiaoxi Zhuang
Xiaoxi Zhuang University of Chicago
Yoo-Hun Suh
Yoo-Hun Suh Seoul National University

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