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Byoung Joo Gwag

Byoung Joo Gwag

D-Index & Metrics

Neuroscience

D-Index
52
Citations
10803
World Ranking
5298
National Ranking
26

Overview

Byoung Joo Gwag is a researcher affiliated with Yonsei University in South Korea, focused primarily on the field of Medicine with significant contributions in Biochemistry, Genetics, and Molecular Biology. Their work encompasses various specialized subfields such as Epidemiology, Neurology, Molecular Biology, Emergency Medicine, and Internal Medicine.

Their research topics cover a range of areas related to acute clinical and biological conditions. Notable topics include:

  • Acute Ischemic Stroke Management
  • Cardiac Arrest and Resuscitation
  • S100 Proteins and Annexins
  • Venous Thromboembolism Diagnosis and Management
  • Human-Animal Interaction Studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments

Byoung Joo Gwag has contributed to several publications, including notable papers such as:

  • Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2− production, 2020, Nature Neuroscience
  • Nelonemdaz for Patients With Acute Ischemic Stroke Undergoing Endovascular Reperfusion Therapy: A Randomized Phase II Trial, 2022, Stroke
  • The Rescue on Reperfusion Damage in Cerebral Infarction by Nelonemdaz (RODIN) Trial: Protocol for a Double-Blinded Clinical Trial of Nelonemdaz in Patients with Hyperacute Ischemic Stroke and Endovascular Thrombectomy, 2023, Journal of Stroke
  • Nelonemdaz and Patients With Acute Ischemic Stroke and Mechanical Reperfusion, 2025, JAMA Network Open
  • Rationale and methods of the Antioxidant and NMDA receptor blocker Weans Anoxic brain damage of KorEa OHCA patients (AWAKE) trial, 2022, Trials

Their frequent coauthors include:

  • Jin Soo Lee
  • Ji Sung Lee
  • Chun San An
  • Seong Hwan Ahn
  • Sun U. Kwon

Byoung Joo Gwag's work appears regularly in journals such as Stroke, Journal of Stroke, Nature Neuroscience, JAMA Network Open, and Applied Animal Behaviour Science.

Best Publications

  • The Role of Zinc in Selective Neuronal Death After Transient Global Cerebral Ischemia

    Jae Young Koh;Sang W. Suh;Byoung J. Gwag;Yong Y. He

  • Mediation of neuronal apoptosis by enhancement of outward potassium current.

    Shan Ping Yu;Chen Hsiung Yeh;Stefano L. Sensi;Byoung J. Gwag

  • The Highly Conserved DRY Motif of Class A G Protein-Coupled Receptors: Beyond the Ground State

    G. Enrico Rovati;Valérie Capra;Richard R. Neubig

  • Potentiated necrosis of cultured cortical neurons by neurotrophins

    Jae-Young Koh;Byoung J. Gwag;Doug Lobner;Dennis W. Choi

  • Cellular and molecular pathways of ischemic neuronal death.

    Seok Joon Won;Doo Yeon Kim;Byoung Joo Gwag

  • Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals.

    Y.-H. Kim;E.Y. Kim;B.J. Gwag;S. Sohn

  • Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro

    B.J. Gwag;D. Lobner;J.Y. Koh;M.B. Wie

  • Staurosporine-Induced Neuronal Apoptosis

    Jae-Young Koh;Myung B. Wie;Byoung J. Gwag;Stefano L. Sensi

  • Proapoptotic Effects of Tau Cleavage Product Generated by Caspase-3

    Chul Woong Chung;Yu Hyun Song;In Ki Kim;Won Joo Yoon

  • Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2-production

    Heejung Chun;Hyeonjoo Im;You Jung Kang;Yunha Kim

  • Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures

    Eun Young Kim;Jae Young Koh;Yang Hee Kim;Seonghyang Sohn

  • Slowly triggered excitotoxicity occurs by necrosis in cortical cultures

    B. J. Gwag;J. Y. Koh;J. A. Demaro;H. S. Ying

  • Necrosis and apoptosis after retinal ischemia: involvement of NMDA-mediated excitotoxicity and p53.

    Choun Ki Joo;Jun Sub Choi;Hyuk W. Ko;Kye Yoon Park

  • Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice.

    Jin Hwan Lee;Sun Mi Won;Jaehong Suh;Sun Joo Son

  • Co-accumulation of vascular endothelial growth factor with β-amyloid in the brain of patients with Alzheimer's disease

    Seung-Pil Yang;Dong-Goo Bae;Hyo Jung Kang;Byoung Joo Gwag

  • Ectopic Expression of the Catalytic Subunit of Telomerase Protects against Brain Injury Resulting from Ischemia and NMDA-Induced Neurotoxicity

    Hyo Jung Kang;Yoon Sik Choi;Seung Beom Hong;Kee Won Kim

  • Cyclosporine induces neuronal apoptosis and selective oligodendrocyte death in cortical cultures.

    John W. McDonald;Mark P. Goldberg;Byoung J. Gwag;Shu Ing Chi

  • Calcium ionophores can induce either apoptosis or necrosis in cultured cortical neurons

    B. J. Gwag;L. M T Canzoniero;S. L. Sensi;J. A. Demaro

  • Phosphatidylinositol 3-kinase-mediated regulation of neuronal apoptosis and necrosis by insulin and IGF-I.

    Bo Rum Ryu;Hyuk Wan Ko;Ilo Jou;Jai Sung Noh

  • Effects of estrogen on lifespan and motor functions in female hSOD1 G93A transgenic mice.

    Chan-Il Choi;Young-Don Lee;Byoung Joo Gwag;Sung Ig Cho

  • Brain-derived neurotrophic factor can act as a pronecrotic factor through transcriptional and translational activation of NADPH oxidase.

    Sun H. Kim;Seok J. Won;Seonghyang Sohn;Hyuk J. Kwon

Frequent Co-Authors

Joe E. Springer
Joe E. Springer University of Kentucky
Dennis W. Choi
Dennis W. Choi Stony Brook University
Eun-hye Joe
Eun-hye Joe Ajou University
Hoon Ryu
Hoon Ryu Korea Institute of Science and Technology
C. Justin Lee
C. Justin Lee Institute for Basic Science
Oh Young Bang
Oh Young Bang Samsung Medical Center
M. Margarita Behrens
M. Margarita Behrens Salk Institute for Biological Studies
Lorella M.T. Canzoniero
Lorella M.T. Canzoniero University of Sannio
Daesoo Kim
Daesoo Kim Korea Advanced Institute of Science and Technology
Young Chul Sung
Young Chul Sung Pohang University of Science and Technology

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