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Molecular Biology

D-Index
47
Citations
6922
World Ranking
2758
National Ranking
16

Overview

Pyung-Lim Han is affiliated with Ewha Womans University in South Korea and conducts research primarily in the fields of Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Behavioral Neuroscience, Biological Psychiatry, Molecular Biology, Neurology, and Social Psychology.

Their research covers diverse topics such as Stress Responses and Cortisol, Tryptophan and brain disorders, Neuroinflammation and Neurodegeneration Mechanisms, Neuroendocrine regulation and behavior, Alzheimer's disease research and treatments, Extracellular vesicles in disease, and Gut microbiota and health.

Recent publications authored or co-authored by Pyung-Lim Han include:

  • Repeated exposure with short-term behavioral stress resolves pre-existing stress-induced depressive-like behavior in mice (2021, Nature Communications)
  • Extracellular Vesicles from Gram-positive and Gram-negative Probiotics Remediate Stress-Induced Depressive Behavior in Mice (2022, Molecular Neurobiology)
  • Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice (2020, Communications Biology)
  • Lactobacillus-derived extracellular vesicles counteract Aβ42-induced abnormal transcriptional changes through the upregulation of MeCP2 and Sirt1 and improve Aβ pathology in Tg-APP/PS1 mice (2023, Experimental & Molecular Medicine)
  • Behavioral Engagement With Playable Objects Resolves Stress-Induced Adaptive Changes by Reshaping the Reward System (2021, Biological Psychiatry)

Frequent co-authors collaborating with Pyung-Lim Han include:

  • Hye-Jin Kwon
  • Juli Choi
  • Eun Hwa Lee
  • Jin-Young Park
  • Yoon-Keun Kim

They have published multiple articles in several key venues, including:

  • Experimental Neurobiology
  • Molecular Neurobiology
  • Experimental & Molecular Medicine
  • Nature Communications
  • Communications Biology

Best Publications

  • HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain

    Jung-Bin Kim;Joon Sig Choi;Young-Mi Yu;Kihoon Nam

  • The Drosophila learning and memory gene rutabaga encodes a Ca2+/Calmodulin-responsive adenylyl cyclase.

    Lonny R. Levin;Pyung Lim Han;Paul M. Hwang;Paul G. Feinstein

  • Vitamin D3 Up-Regulated Protein 1 Mediates Oxidative Stress Via Suppressing the Thioredoxin Function

    Eun Sung Junn;Seung Hyun Han;Joo Young Im;Young Yang

  • Preferential expression of the drosophila rutabaga gene in mushroom bodies, neural centers for learning in insects

    Pyung Lim Han;Lonny R. Levin;Randall R. Reed;Randall R. Reed;Ronald L. Davis

  • Glycyrrhizic acid affords robust neuroprotection in the postischemic brain via anti-inflammatory effect by inhibiting HMGB1 phosphorylation and secretion.

    Seung-Woo Kim;Yinchuan Jin;Joo-Hyun Shin;Il-Doo Kim

  • Optimization of chronic stress paradigms using anxiety- and depression-like behavioral parameters

    Kyoung-Shim Kim;Pyung-Lim Han

  • Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase.

    Ko Woon Lee;Jang Hee Hong;Jang Hee Hong;In Young Choi;Yongzhe Che

  • Intranasal delivery of HMGB1 siRNA confers target gene knockdown and robust neuroprotection in the postischemic brain.

    Il Doo Kim;Joo Hyun Shin;Seung Woo Kim;Sunghyun Choi

  • Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult.

    Chun Shu Piao;Jung Bin Kim;Pyung Lim Han;Ja Kyeong Lee

  • Inhibition of the Cerebral Ischemic Injury by Ethyl Pyruvate With a Wide Therapeutic Window

    Young Mi Yu;Jung Bin Kim;Kang Woo Lee;Seong Yun Kim

  • The cyclic AMP system and Drosophila learning

    Ronald L. Davis;Jim Cherry;Brigitte Dauwalder;Pyung Lim Han

  • Activation of c-Jun N-terminal Kinase Antagonizes an Anti-apoptotic Action of Bcl-2

    Jihyun Park;Injung Kim;Young Jun Oh;Ko Woon Lee

  • Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action.

    Kyoung Shim Kim;Ko Woon Lee;Kang Woo Lee;Joo Young Im

  • NADPH Oxidase Mediates Depressive Behavior Induced by Chronic Stress in Mice

    Ji Seon Seo;Jin Young Park;Juli Choi;Tae Kyung Kim

  • Metagenome Analysis of Bodily Microbiota in a Mouse Model of Alzheimer Disease Using Bacteria-derived Membrane Vesicles in Blood

    Jin Young Park;Juli Choi;Yunjin Lee;Jung Eun Lee

  • Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress

    Kang Woo Lee;Jung Bin Kim;Ji Seon Seo;Tae Kyung Kim

  • The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein.

    Catherine A. Dye;Ja Kyeong Lee;Ja Kyeong Lee;Richard C. Atkinson;Rachel Brewster

  • Cyclooxygenase-2-dependent neuronal death proceeds via superoxide anion generation.

    Joo Young Im;Joo Young Im;Doyeun Kim;Sang Gi Paik;Pyung Lim Han

  • Ca2+‐Mediated Activation of c‐Jun N‐Terminal Kinase and Nuclear Factor κB by NMDA in Cortical Cell Cultures

    Hyuk Wan Ko;Kye Yoon Park;Hansin Kim;Pyung Lim Han

  • Repression of Tau Hyperphosphorylation by Chronic Endurance Exercise in Aged Transgenic Mouse Model of Tauopathies

    Yea Hyun Leem;Hwa Ja Lim;Sun Bo Shim;Joon Yong Cho

Frequent Co-Authors

Eui Ju Choi
Eui Ju Choi Korea University
Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Bong Hyun Chung
Bong Hyun Chung Korea Research Institute of Bioscience and Biotechnology
Jae-Young Koh
Jae-Young Koh University of Ulsan
Yoon-Keun Kim
Yoon-Keun Kim Pohang University of Science and Technology
Hee-Sup Shin
Hee-Sup Shin Institute for Basic Science
Byoung Joo Gwag
Byoung Joo Gwag Yonsei University
Michelle E. Ehrlich
Michelle E. Ehrlich Icahn School of Medicine at Mount Sinai
Kirill A. Martemyanov
Kirill A. Martemyanov Scripps Research Institute
Baoji Xu
Baoji Xu Scripps Research Institute

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