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Neuroscience

D-Index
44
Citations
8465
World Ranking
7124
National Ranking
319

Overview

Florence Noble is affiliated with Université Paris Cité in France. Their research spans multiple areas within neuroscience and related biomedical sciences, with a focus on neuropeptides, receptor signaling, and physiological responses.

The primary fields of study for Florence Noble include Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broader areas, their work concentrates on subfields such as Cellular and Molecular Neuroscience, Molecular Biology, Physiology, Behavioral Neuroscience, and Cognitive Neuroscience.

Key topics investigated by Noble encompass Neuropeptides and Animal Physiology, Neurotransmitter Receptor Influence on Behavior, Receptor Mechanisms and Signaling, Pharmacological Receptor Mechanisms and Effects, Stress Responses and Cortisol, Pain Mechanisms and Treatments, and Neuroendocrine Regulation and Behavior.

Frequent publication venues for their research include Neuroscience Applied, Frontiers in Pharmacology, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Psychiatry, and Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Significant recent papers authored or co-authored by Florence Noble are:

  • Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System, 2022, Frontiers in Pharmacology
  • TREK1 channel activation as a new analgesic strategy devoid of opioid adverse effects, 2020, British Journal of Pharmacology
  • Oxycodone, an opioid like the others?, 2023, Frontiers in Psychiatry
  • Behavioral sensitization to psychostimulants and opioids: What is known in rodents and what still needs to be explored in humans?, 2023, Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • Activation of the Mu-Delta Opioid Receptor Heteromers Blocks Morphine Rewarding Effects, 2023, The International Journal of Neuropsychopharmacology

Florence Noble has collaborated frequently with several researchers, including:

  • Nicolas Marie
  • Raymond Mongeau
  • Virginie Beray-Berthat
  • Claire Leconte
  • Loïc Clémenceau

Best Publications

  • International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors.

    Florence Noble;Stephen A. Wank;Jacqueline N. Crawley;Jacques Bradwejn

  • Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype.

    Catherine Heurteaux;Guillaume Lucas;Nicolas Guy;Malika El Yacoubi

  • CCK-B receptor: chemistry, molecular biology, biochemistry and pharmacology

    Florence Noble;Bernard P. Roques

  • Δ9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect

    Olga Valverde;Florence Noble;Françoise Beslot;Valérie Daugé

  • New treatments for cocaine dependence: a focused review.

    Laurent Karila;David Gorelick;Aviv Weinstein;Florence Noble

  • "Mixed inhibitor-prodrug" as a new approach toward systemically active inhibitors of enkephalin-degrading enzymes.

    Marie Claude Fournie-Zaluski;Pascal Coric;Serge Turcaud;Evelyne Lucas

  • Blockade of Acute Microglial Activation by Minocycline Promotes Neuroprotection and Reduces Locomotor Hyperactivity after Closed Head Injury in Mice: A Twelve-Week Follow-Up Study

    Shadi Homsi;Tomaso Piaggio;Nicole Croci;Florence Noble

  • Opioid receptor desensitization: mechanisms and its link to tolerance.

    Stéphane Allouche;Florence Noble;Nicolas Marie;Nicolas Marie;Nicolas Marie

  • Inhibition of the enkephalin-metabolizing enzymes by the first systemically active mixed inhibitor prodrug RB 101 induces potent analgesic responses in mice and rats.

    F Noble;J M Soleilhac;E Soroca-Lucas;S Turcaud

  • Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice.

    Julie Salzmann;Cynthia Marie-claire;Stéphanie Le Guen;Bernard P Roques

  • Reduction of opioid dependence by the CB1 antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction

    Magdalena Mas-Nieto;Blandine Pommier;Eleni T Tzavara;Anne Caneparo

  • Nociceptin/Orphanin FQ Metabolism: Role of Aminopeptidase and Endopeptidase 24.15

    Jose-Luis Montiel;Fabrice Cornille;Bernard P. Roques;Florence Noble

  • Cytoskeletal genes regulation by chronic morphine treatment in rat striatum

    Cynthia Marie-Claire;Cindie Courtin;Bernard P Roques;Florence Noble

  • Modulation of opioid antinociception by CCK at the supraspinal level : evidence of regulatory mechanisms between CCK and enkephalin systems in the control of pain

    Florence Noble;Muriel Derrien;Bernard P. Roques

  • Phosphinic derivatives as new dual enkephalin-degrading enzyme inhibitors: synthesis, biological properties, and antinociceptive activities.

    Huixiong Chen;Florence Noble;Aurélie Mothé;Hervé Meudal

  • Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors.

    M. Mas Nieto;S.L.E. Guen;B.L. Kieffer;B.P. Roques

  • Potent and systemically active aminopeptidase N inhibitors designed from active-site investigation.

    Marie Claude Fournie-Zaluski;Pascale Coric;Serge Turcaud;Luce Bruetschy

  • Differential desensitization of μ- and δ- opioid receptors in selected neural pathways following chronic morphine treatment

    Florence Noble;Brian M. Cox

  • Synthesis and Biological Properties of New Constrained CCK-B Antagonists: Discrimination of Two Affinity States of the CCK-B Receptor on Transfected CHO Cells

    Bruno Bellier;Isabelle McCort-Tranchepain;Bertrand Ducos;Sophie Danascimento

  • Association of aminopeptidase N and endopeptidase 24.15 inhibitors potentiate behavioral effects mediated by nociceptin/orphanin FQ in mice

    Florence Noble;Bernard P Roques

  • Deletion of CCK2 Receptor in Mice Results in an Upregulation of the Endogenous Opioid System

    Blandine Pommier;Françoise Beslot;Axelle Simon;Matthieu Pophillat

  • Polyamine deficient diet to relieve pain hypersensitivity.

    Cyril Rivat;Philippe Richebé;Emilie Laboureyras;Jean Paul Laulin

  • Differential Regulation of D1 Dopamine Receptor‐ and of A2a Adenosine Receptor‐Stimulated Adenylyl Cyclase by μ‐, δ1‐, and δ2‐Opioid Agonists in Rat Caudate Putamen

    Florence Noble;Brian M. Cox

  • Chronic morphine treatment modulates the extracellular levels of endogenous enkephalins in rat brain structures involved in opiate dependence: a microdialysis study.

    Magdalena Mas Nieto;Jodie Wilson;Annie Cupo;Bernard P Roques

Frequent Co-Authors

Kim B. Seroogy
Kim B. Seroogy University of Cincinnati
Jacqueline N. Crawley
Jacqueline N. Crawley University of California, Davis
Guy Simonnet
Guy Simonnet University of Bordeaux
Andreas Zimmer
Andreas Zimmer University of Bonn
Philip Gorwood
Philip Gorwood Université Paris Cité
Jacques Bradwejn
Jacques Bradwejn University of Ottawa
Henri-Jean Aubin
Henri-Jean Aubin University of Paris-Saclay
Aviv Weinstein
Aviv Weinstein Ariel University
Olga Valverde
Olga Valverde Pompeu Fabra University
Jean-Luc Martinot
Jean-Luc Martinot École Normale Supérieure Paris-Saclay

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