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D-Index
55
Citations
8694
World Ranking
15259
National Ranking
605

Overview

Jean Mazella is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research primarily spans the fields of medicine, neuroscience, and biochemistry, genetics, and molecular biology. More specifically, their work involves molecular biology, neurology, pharmacology, cellular and molecular neuroscience, and physiology.

The scientist's research covers multiple interconnected topics including receptor mechanisms and signaling, neuropeptides and animal physiology, neurological disorders and treatments, pharmacogenetics and drug metabolism, pharmacological receptor mechanisms and effects, bioactive natural compounds, and neuroinflammation and neurodegeneration mechanisms.

Jean Mazella has published in a variety of peer-reviewed journals. Notable recent papers include:

  • "THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors" (2021) in the British Journal of Pharmacology
  • "Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia" (2020) in the Journal of Ethnopharmacology
  • "Sortilin-derived peptides promote pancreatic beta-cell survival through CREB signaling pathway" (2021) in Pharmacological Research
  • "Deciphering Mechanisms of Action of Sortilin/Neurotensin Receptor-3 in the Proliferation Regulation of Colorectal and Other Cancers" (2022) in International Journal of Molecular Sciences
  • "Serum sortilin-derived propeptide concentrations as markers of depression in chronic stroke" (2025) in Journal of the Neurological Sciences

Frequent coauthors collaborating with Jean Mazella include:

  • Catherine Heurteaux
  • Marc Borsotto
  • Sophie Béraud-Dufour
  • Thierry Coppola
  • Nicolas Blondeau

The scientist commonly publishes work in journals such as the British Journal of Pharmacology, Journal of Ethnopharmacology, Pharmacological Research, International Journal of Molecular Sciences, and Journal of the Neurological Sciences.

Best Publications

  • Neurotensin and neurotensin receptors.

    Jean-Pierre Vincent;Jean Mazella;Patrick Kitabgi

  • The 100-kDa Neurotensin Receptor Is gp95/Sortilin, A Non-G-Protein-coupled Receptor

    Jean Mazella;Nicole Zsürger;Valérie Navarro;Joëlle Chabry

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

    Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  • Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain.

    Jean Mazella;Jean-Marie Botto;Eric Guillemare;Thierry Coppola

  • Contulakin-G, an O-glycosylated invertebrate neurotensin

    A. Grey Craig;Thomas Norberg;David Griffin;Carl Hoeger

  • Localization of the Somatostatin Receptor SST2A in Rat Brain Using a Specific Anti-Peptide Antibody

    Pascal Dournaud;Yi Z. Gu;Agnes Schonbrunn;Jean Mazella

  • Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design

    Jean Mazella;Olivier Petrault;Guillaume Lucas;Emmanuel Deval

  • Pharmacology and biochemistry of neurotensin receptors.

    P Kitabgi;F Checler;J Mazella;J P Vincent

  • Distribution of neurotensin binding sites in rat brain: A light microscopic radioautographic study using monoiodo [125I]Tyr3-neurotensin

    E. Moyse;W. Rostène;M. Vial;K. Leonard

  • Involvement of the Neurotensin Receptor-3 in the Neurotensin-Induced Migration of Human Microglia

    Stéphane Martin;Jean-Pierre Vincent;Jean Mazella

  • Sortilin/neurotensin receptor-3: a new tool to investigate neurotensin signaling and cellular trafficking?

    Jean Mazella

  • Differential internalization of somatostatin in COS-7 cells transfected with SST1 and SST2 receptor subtypes : A confocal microscopic study using novel fluorescent somatostatin derivatives

    Dominique Nouel;Georges Gaudriault;Mariette Houle;Terry Reisine

  • Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system

    Philippe Sarret;Pascale Krzywkowski;Laura Segal;Morten S. Nielsen

  • Preparation of neurotensin selectively iodinated on the tyrosine 3 residue. Biological activity and binding properties on mammalian neurotensin receptors.

    Jean-Louis Sadoul;Jean Mazella;Shimon Amar;Patrick Kitabgi

  • Identification of the Receptor Subtype Involved in the Analgesic Effect of Neurotensin

    Isabelle Dubuc;Philippe Sarret;Catherine Labbé-Jullié;Jean-Marie Botto

  • Neurotensin receptor–1 and –3 complex modulates the cellular signaling of neurotensin in the HT29 cell line

    Stéphane Martin;Valérie Navarro;Jean Pierre Vincent;Jean Mazella

  • Monoiodo-[Trp11]neurotensin, a highly radioactive ligand of neurotensin receptors. Preparation, biological activity, and binding properties to rat brain synaptic membranes.

    J Mazella;C Poustis;C Labbe;F Checler

  • Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines.

    Claude Dal Farra;Philippe Sarret;Valérie Navarro;Jean‐Marie Botto

  • Implication of various forms of neurotensin receptors in the mechanism of internalization of neurotensin in cerebral neurons.

    J Chabry;G Gaudriault;J P Vincent;J Mazella

  • Mutagenesis and Modeling of the Neurotensin Receptor NTR1 IDENTIFICATION OF RESIDUES THAT ARE CRITICAL FOR BINDING SR 48692, A NONPEPTIDE NEUROTENSIN ANTAGONIST

    Catherine Labbé-Jullié;Séverine Barroso;Delphine Nicolas-Etève;Jean-Louis Reversat

Frequent Co-Authors

Jean-Pierre Vincent
Jean-Pierre Vincent Centre national de la recherche scientifique, CNRS
Catherine Heurteaux
Catherine Heurteaux Centre national de la recherche scientifique, CNRS
Patrick Kitabgi
Patrick Kitabgi Grenoble Alpes University
Philippe Sarret
Philippe Sarret Université de Sherbrooke
Frédéric Checler
Frédéric Checler Grenoble Alpes University
Hans-Jürgen Kreienkamp
Hans-Jürgen Kreienkamp Universität Hamburg
Jean-Martin Beaulieu
Jean-Martin Beaulieu University of Toronto
Claude Granier
Claude Granier Centre national de la recherche scientifique, CNRS
Claus Munck Petersen
Claus Munck Petersen Aarhus University
Nasser Haddjeri
Nasser Haddjeri Claude Bernard University Lyon 1

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