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Anders Nykjaer

Anders Nykjaer

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
20561
World Ranking
6238
National Ranking
55

Overview

Anders Nykjaer is a researcher affiliated with Aarhus University in Denmark. Their work primarily spans the fields of biochemistry, genetics, molecular biology, neuroscience, and medicine, with a significant focus on molecular biology and cellular and molecular neuroscience.

The research topics explored by Nykjaer include:

  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • Mitochondrial function and pathology
  • Amyotrophic lateral sclerosis research
  • Neurogenetic and muscular disorders research
  • Advanced proteomics techniques and applications
  • Neuroscience and neuropharmacology research

Nykjaer has contributed to several scientific publications, with notable papers including:

  • "Sortilin as a Biomarker for Cardiovascular Disease Revisited" (2021) in Frontiers in Cardiovascular Medicine
  • "Finding memo: versatile interactions of the VPS10p-Domain receptors in Alzheimer's disease" (2022) in Molecular Neurodegeneration
  • "Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease" (2021) in Kidney International
  • "Altered dopaminergic firing pattern and novelty response underlie ADHD-like behavior of SorCS2-deficient mice" (2021) in Translational Psychiatry
  • "Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease" (2021) in Acta Neuropathologica Communications

The scientist frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Frontiers in Cardiovascular Medicine
  • Molecular Neurodegeneration
  • Kidney International

Nykjaer collaborates regularly with several researchers, including:

  • Mads Kjølby
  • Alena Salašová
  • Lilian Kisiswa
  • Olav M. Andersen
  • Sadegh Nabavi

Best Publications

  • ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTR and Sortilin

    Henry K. Teng;Kenneth K. Teng;Ramee Lee;Saundrene Wright

  • Sortilin is essential for proNGF-induced neuronal cell death

    Anders Nykjaer;Ramee Lee;Kenneth K. Teng;Pernille Jansen;Pernille Jansen

  • An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3

    Anders Nykjaer;Duska Dragun;Diego Walther;Henrik Vorum

  • Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.

    Olav M. Andersen;Juliane Reiche;Vanessa Schmidt;Michael Gotthardt

  • Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes.

    A Nykjaer;C M Petersen;B Møller;P H Jensen

  • Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin

    Fenghua Hu;Thihan Padukkavidana;Christian Bjerggaard Vægter;Owen Brady

  • The sortilin cytoplasmic tail conveys Golgi–endosome transport and binds the VHS domain of the GGA2 sorting protein

    Morten S. Nielsen;Peder Madsen;Erik I. Christensen;Anders Nykjær

  • Megalin Knockout Mice as an Animal Model of Low Molecular Weight Proteinuria

    Jörg-Robert Leheste;Boris Rolinski;Henrik Vorum;Jan Hilpert

  • MOLECULAR IDENTIFICATION OF A NOVEL CANDIDATE SORTING RECEPTOR PURIFIED FROM HUMAN BRAIN BY RECEPTOR-ASSOCIATED PROTEIN AFFINITY CHROMATOGRAPHY

    Claus M. Petersen;Morten S. Nielsen;Anders Nykjær;Linda Jacobsen

  • Role of endocytosis in cellular uptake of sex steroids.

    Annette Hammes;Thomas K. Andreassen;Robert Spoelgen;Jens Raila

  • Sortilin Controls Intracellular Sorting of Brain-Derived Neurotrophic Factor to the Regulated Secretory Pathway

    Zhe-Yu Chen;Alessandro Ieraci;Henry Teng;Henning Dall

  • p75NTR--live or let die.

    Anders Nykjaer;Thomas E Willnow;Claus Munck Petersen

  • Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes.

    Anders Nykjær;Massimo Conese;Erik I. Christensen;David Olson

  • Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).

    Anders Nykjaer;John C. Fyfe;Renata Kozyraki;Jörg Robert Leheste

  • Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

    Pernille Jansen;Klaus Giehl;Klaus Giehl;Jens R Nyengaard;Kenneth Teng

  • VPS10P-domain receptors — regulators of neuronal viability and function

    Thomas E. Willnow;Claus M. Petersen;Anders Nykjaer

  • The low-density lipoprotein receptor gene family: a cellular Swiss army knife?

    Anders Nykjaer;Thomas E. Willnow

  • Molecular Characterization of a Novel Human Hybrid-type Receptor That Binds the α2-Macroglobulin Receptor-associated Protein

    Linda Jacobsen;Peder Madsen;Søren K. Moestrup;Anders H. Lund

  • Lipoprotein receptors: New roles for ancient proteins

    Thomas E. Willnow;Anders Nykjaer;Joachim Herz

  • Sort1, Encoded by the Cardiovascular Risk Locus 1p13.3, Is a Regulator of Hepatic Lipoprotein Export

    Mads Kjolby;Olav M. Andersen;Tilman Breiderhoff;Anja W. Fjorback

Frequent Co-Authors

Thomas E. Willnow
Thomas E. Willnow Max Delbrück Center for Molecular Medicine
Jørgen Gliemann
Jørgen Gliemann Aarhus University
Claus Munck Petersen
Claus Munck Petersen Aarhus University
Peder Madsen
Peder Madsen Aarhus University
Erik Ilsø Christensen
Erik Ilsø Christensen Aarhus University
Peter A. Andreasen
Peter A. Andreasen Aarhus University
Christian Jacobsen
Christian Jacobsen Aarhus University
Søren K. Moestrup
Søren K. Moestrup Aarhus University
Barbara L. Hempstead
Barbara L. Hempstead Cornell University

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