Francis S. Lee

Research.com Recognitions

• 2016 - Member of the National Academy of Medicine (NAM)
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions

  Vaishnav Krishnan;Ming Hu Han;Danielle L. Graham;Olivier Berton

  2615
  Citations

• Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

  Zhe-Yu Chen;Deqiang Jing;Kevin G. Bath;Alessandro Ieraci

  1565
  Citations

• ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTR and Sortilin

  Henry K. Teng;Kenneth K. Teng;Ramee Lee;Saundrene Wright

  1260
  Citations

• Variant Brain-Derived Neurotrophic Factor (BDNF) (Met66) Alters the Intracellular Trafficking and Activity-Dependent Secretion of Wild-Type BDNF in Neurosecretory Cells and Cortical Neurons

  Zhe Yu Chen;Paresh D. Patel;Gayatree Sant;Chui Xiang Meng

  1259
  Citations

• Neurotrophin signalling in health and disease.

  Moses V. Chao;Rithwick Rajagopal;Francis S. Lee

  768
  Citations

• A Genetic Variant BDNF Polymorphism Alters Extinction Learning in Both Mouse and Human

  Fatima Soliman;Charles E. Glatt;Kevin G. Bath;Liat Levita

  664
  Citations

• Adolescent mental health—Opportunity and obligation

  Francis S. Lee;Hakon Heimer;Jay N. Giedd;Edward S Lein

  609
  Citations

• Activation of Trk neurotrophin receptors in the absence of neurotrophins

  Francis S. Lee;Moses V. Chao

  595
  Citations

• Neuronal release of proBDNF

  Jianmin Yang;Chia-Jen Siao;Guhan Nagappan;Tina Marinic

  587
  Citations

• Sortilin Controls Intracellular Sorting of Brain-Derived Neurotrophic Factor to the Regulated Secretory Pathway

  Zhe-Yu Chen;Alessandro Ieraci;Henry Teng;Henning Dall

  487
  Citations

• DSM-5 and RDoC: progress in psychiatry research?

  B. J. Casey;Nicholas John Craddock;Bruce N. Cuthbert;Steven E. Hyman

  454
  Citations

• Altered fear learning across development in both mouse and human.

  Siobhan S. Pattwell;Stéphanie Duhoux;Catherine A. Hartley;David C. Johnson

  444
  Citations

• The microbiota regulate neuronal function and fear extinction learning

  Coco Chu;Mitchell H. Murdock;Deqiang Jing;Tae Hyung Won

  427
  Citations

• Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex.

  Rong-Jian Liu;Francis S. Lee;Xiao-Yuan Li;Francis Bambico

  418
  Citations

• Variant BDNF (Val66Met) impact on brain structure and function.

  Kevin G. Bath;Francis S. Lee

  416
  Citations

• Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice

  Sergey V Shmelkov;Adília Hormigo;Adília Hormigo;Adília Hormigo;Deqiang Jing;Catia C Proenca;Catia C Proenca

  386
  Citations

• BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR

  Joan M. Carboni;Mark Wittman;Zheng Yang;Francis Lee

  375
  Citations

• Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes.

  Rithwick Rajagopal;Zhe-Yu Chen;Francis S. Lee;Moses V. Chao

  363
  Citations

• Variant Brain-Derived Neurotrophic Factor Val66Met Polymorphism Alters Vulnerability to Stress and Response to Antidepressants

  Hui Yu;Dong-Dong Wang;Yue Wang;Ting Liu

  358
  Citations

• proBDNF Negatively Regulates Neuronal Remodeling, Synaptic Transmission, and Synaptic Plasticity in Hippocampus

  Jianmin Yang;Lauren C. Harte-Hargrove;Chia-Jen Siao;Tina Marinic

  356
  Citations

• Early-life stress has persistent effects on amygdala function and development in mice and humans

  Matthew Malter Cohen;Deqiang Jing;Rui R. Yang;Nim Tottenham;Nim Tottenham

  324
  Citations