2016 - Member of the National Academy of Medicine (NAM)
Member of the Association of American Physicians
His primary areas of investigation include Neuroscience, Neurotrophic factors, Brain-derived neurotrophic factor, Neurotrophin and Tropomyosin receptor kinase B. His Neuroscience study combines topics from a wide range of disciplines, such as Synaptic plasticity, Psychological resilience, Neurotransmission and Anxiety. His Neurotrophic factors study introduces a deeper knowledge of Internal medicine.
The study incorporates disciplines such as Dendritic spine, Hippocampal formation, Allele, Genotype and Intracellular in addition to Brain-derived neurotrophic factor. His Neurotrophin research is multidisciplinary, relying on both Transgene and Cell biology. The Tropomyosin receptor kinase B study combines topics in areas such as Tropomyosin receptor kinase A and Neuron.
Francis S. Lee mainly focuses on Neuroscience, Neurotrophic factors, Brain-derived neurotrophic factor, Internal medicine and Endocrinology. He interconnects Synaptic plasticity, Neurotrophin and Anxiety in the investigation of issues within Neuroscience. In his research on the topic of Neurotrophin, Tropomyosin receptor kinase A is strongly related with Cell biology.
His Neurotrophic factors research is multidisciplinary, incorporating elements of Phenotype, Growth factor, Neurogenesis, Neuroplasticity and Single-nucleotide polymorphism. His Brain-derived neurotrophic factor research incorporates elements of Neurotransmission, Long-term potentiation, Molecular biology, Tropomyosin receptor kinase B and Epigenetics. His studies deal with areas such as Exposure therapy and Oncology as well as Internal medicine.
His scientific interests lie mostly in Neuroscience, Internal medicine, Extinction, Prefrontal cortex and Endocrinology. His Neuroscience study integrates concerns from other disciplines, such as Schizophrenia and Endocannabinoid system. Francis S. Lee focuses mostly in the field of Internal medicine, narrowing it down to topics relating to Oncology and, in certain cases, Brain-derived neurotrophic factor, Treatment outcome, Val66met polymorphism and Dosing.
He combines subjects such as Infralimbic cortex and Prolonged exposure therapy with his study of Extinction. His study in Endocrinology is interdisciplinary in nature, drawing from both Neurotrophic factors, Anandamide, Allele and Fatty acid amide hydrolase. His Neurotrophic factors research integrates issues from Neurotrophin, Hormone, Cell biology, Thrombosis and Physical exercise.
Neuroscience, Prefrontal cortex, Extinction, Psychiatry and Human studies are his primary areas of study. All of his Neuroscience and Basolateral amygdala and Fear learning investigations are sub-components of the entire Neuroscience study. His work carried out in the field of Prefrontal cortex brings together such families of science as Neuroglia, Postsynaptic potential, Dendritic spine, Premovement neuronal activity and Amygdala.
His Amygdala study improves the overall literature in Endocrinology. He has included themes like Infralimbic cortex, Neuroplasticity and Cell type in his Extinction study. His work in Exposure therapy addresses issues such as Internal medicine, which are connected to fields such as Prolonged exposure therapy.
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Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions
Vaishnav Krishnan;Ming Hu Han;Danielle L. Graham;Olivier Berton.
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior
Zhe-Yu Chen;Deqiang Jing;Kevin G. Bath;Alessandro Ieraci.
Variant Brain-Derived Neurotrophic Factor (BDNF) (Met66) Alters the Intracellular Trafficking and Activity-Dependent Secretion of Wild-Type BDNF in Neurosecretory Cells and Cortical Neurons
Zhe Yu Chen;Paresh D. Patel;Gayatree Sant;Chui Xiang Meng.
The Journal of Neuroscience (2004)
ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTR and Sortilin
Henry K. Teng;Kenneth K. Teng;Ramee Lee;Saundrene Wright.
The Journal of Neuroscience (2005)
Neurotrophin signalling in health and disease.
Moses V. Chao;Rithwick Rajagopal;Francis S. Lee.
Clinical Science (2006)
A Genetic Variant BDNF Polymorphism Alters Extinction Learning in Both Mouse and Human
Fatima Soliman;Charles E. Glatt;Kevin G. Bath;Liat Levita.
Activation of Trk neurotrophin receptors in the absence of neurotrophins
Francis S. Lee;Moses V. Chao.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Neuronal release of proBDNF
Jianmin Yang;Chia-Jen Siao;Guhan Nagappan;Tina Marinic.
Nature Neuroscience (2009)
Sortilin Controls Intracellular Sorting of Brain-Derived Neurotrophic Factor to the Regulated Secretory Pathway
Zhe-Yu Chen;Alessandro Ieraci;Henry Teng;Henning Dall.
The Journal of Neuroscience (2005)
Variant BDNF (Val66Met) impact on brain structure and function.
Kevin G. Bath;Francis S. Lee.
Cognitive, Affective, & Behavioral Neuroscience (2006)
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