World's Best Scientists 2026 revealed!
Barbara L. Hempstead

Barbara L. Hempstead

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
39834
World Ranking
2507
National Ranking
1318

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Barbara L. Hempstead is affiliated with Cornell University in the United States, with a research profile centered on neuroscience and biochemistry. Their work focuses notably on the molecular and cellular mechanisms underlying neuroinflammation, neurodegeneration, and nerve injury and regeneration. The primary fields of study include Neuroscience and Biochemistry, Genetics, and Molecular Biology, with subfields spanning Cellular and Molecular Neuroscience, Molecular Biology, Neurology, Cell Biology, and Spectroscopy.

The scientist's research engages multiple core topics such as:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nerve injury and regeneration
  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Cellular transport and secretion
  • Molecular Sensors and Ion Detection
  • Advanced biosensing and bioanalysis techniques

Barbara L. Hempstead's notable recent papers include:

  • "SorCS2 is required for social memory and trafficking of the NMDA receptor," 2020, Molecular Psychiatry
  • "A Molecular Redox Switch on p21 ras: STRUCTURAL BASIS FOR THE NITRIC OXIDE-p21rasINTERACTION," 2021, UNC Libraries
  • "Small, Nonpeptide p75NTR Ligands Induce Survival Signaling and Inhibit proNGF-Induced Death," 2021, UNC Libraries
  • "Human immunomodulatory ligand B7-1 mediates synaptic remodeling via the p75 neurotrophin receptor," 2022, Journal of Clinical Investigation
  • "Zinc induced structural changes in the intrinsically disordered BDNF Met prodomain confer synaptic elimination," 2020, Metallomics

The frequent coauthors of Barbara L. Hempstead consist of:

  • Francis S. Lee
  • Joanna Giza
  • Jianmin Yang
  • Qian Ma
  • Iva Dincheva

The venues where this scientist most frequently publishes are:

  • Molecular Psychiatry
  • UNC Libraries
  • Journal of Clinical Investigation
  • Metallomics
  • Frontiers in Molecular Neuroscience

Barbara L. Hempstead has received recognition such as membership in the Association of American Physicians. This membership reflects involvement in professional societies relevant to medical and biomedical sciences.

Best Publications

  • Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

    Christopher N. Parkhurst;Guang Yang;Ipe Ninan;Jeffrey N. Savas

  • Regulation of cell survival by secreted proneurotrophins.

    Ramee Lee;Pouneh Kermani;Kenneth K. Teng;Barbara L. Hempstead

  • The trk proto-oncogene product: a signal transducing receptor for nerve growth factor

    David R. Kaplan;Barbara L. Hempstead;Dionisio Martin-Zanca;Moses V. Chao

  • Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

    Zhe-Yu Chen;Deqiang Jing;Kevin G. Bath;Alessandro Ieraci

  • High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor.

    Barbara L. Hempstead;Dionisio Martin-Zanca;David R. Kaplan;Luis F. Parada

  • Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity.

    Petti T. Pang;Henry K. Teng;Eygene Zaitsev;Newton T. Woo

  • ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTR and Sortilin

    Henry K. Teng;Kenneth K. Teng;Ramee Lee;Saundrene Wright

  • Variant Brain-Derived Neurotrophic Factor (BDNF) (Met66) Alters the Intracellular Trafficking and Activity-Dependent Secretion of Wild-Type BDNF in Neurosecretory Cells and Cortical Neurons

    Zhe Yu Chen;Paresh D. Patel;Gayatree Sant;Chui Xiang Meng

  • Sortilin is essential for proNGF-induced neuronal cell death

    Anders Nykjaer;Ramee Lee;Kenneth K. Teng;Pernille Jansen;Pernille Jansen

  • p75 and Trk: A two-receptor system

    Moses V. Chao;Barbara L. Hempstead

  • Activation of p75NTR by proBDNF facilitates hippocampal long-term depression

    Newton H Woo;Henry K Teng;Chia-Jen Siao;Cristina Chiaruttini

  • In vitro microvessels for the study of angiogenesis and thrombosis.

    Ying Zheng;Junmei Chen;Michael Craven;Nak Won Choi

  • New insights in the biology of BDNF synthesis and release: implications in CNS function.

    Michael E. Greenberg;Baoji Xu;Bai Lu;Barbara L. Hempstead

  • A Molecular Redox Switch on p21ras STRUCTURAL BASIS FOR THE NITRIC OXIDE-p21ras INTERACTION

    Harry M. Lander;David P. Hajjar;Barbara L. Hempstead;Urooj A. Mirza

  • ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury.

    Michael S Beattie;Anthony W Harrington;Ramee Lee;Ju Young Kim

  • Neuronal release of proBDNF

    Jianmin Yang;Chia-Jen Siao;Guhan Nagappan;Tina Marinic

  • Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization.

    M.J. Donovan;M.I. Lin;P. Wiegn;T. Ringstedt

  • Sortilin Controls Intracellular Sorting of Brain-Derived Neurotrophic Factor to the Regulated Secretory Pathway

    Zhe-Yu Chen;Alessandro Ieraci;Henry Teng;Henning Dall

  • Erythropoietin receptor signalling is required for normal brain development

    Xiaobing Yu;John J. Shacka;Jeffrey B. Eells;Carlos Suarez-Quian

  • Cleavage of proBDNF by tPA/ Plasmin Is Essential for Long-Term

    Petti T. Pang;Henry K. Teng;Eugene Zaitsev;Newton T. Woo

Frequent Co-Authors

Moses V. Chao
Moses V. Chao New York University
Francis S. Lee
Francis S. Lee Cornell University
Shahin Rafii
Shahin Rafii Cornell University
Bai Lu
Bai Lu Tsinghua University
Teresa A. Milner
Teresa A. Milner Cornell University
Kevin G. Bath
Kevin G. Bath Brown University
Luis F. Parada
Luis F. Parada Memorial Sloan Kettering Cancer Center
Raymond B. Birge
Raymond B. Birge Rutgers, The State University of New Jersey
Anders Nykjaer
Anders Nykjaer Aarhus University
Lino Tessarollo
Lino Tessarollo National Institutes of Health

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