D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 85 Citations 35,662 163 World Ranking 1977 National Ranking 1107

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is she best known for?

The fields of study she is best known for:

  • Enzyme
  • Neuron
  • Apoptosis

Cell biology, Nerve growth factor, Receptor, Neurotrophin and Brain-derived neurotrophic factor are her primary areas of study. Her Cell biology study integrates concerns from other disciplines, such as Plasmin, Immunology and Nervous system. The study incorporates disciplines such as Apoptosis and Cell surface receptor in addition to Nerve growth factor.

Her Neurotrophin study incorporates themes from Receptor tyrosine kinase and Programmed cell death. Her work in Trk receptor addresses subjects such as Low-affinity nerve growth factor receptor, which are connected to disciplines such as Molecular biology. As part of the same scientific family, Barbara L. Hempstead usually focuses on Neurotrophic factors, concentrating on Neuroscience and intersecting with Synaptic plasticity.

Her most cited work include:

  • Regulation of cell survival by secreted proneurotrophins. (1358 citations)
  • Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor (1231 citations)
  • The trk proto-oncogene product: a signal transducing receptor for nerve growth factor (1223 citations)

What are the main themes of her work throughout her whole career to date?

Barbara L. Hempstead mainly investigates Cell biology, Neurotrophin, Receptor, Neuroscience and Trk receptor. Her research in Cell biology intersects with topics in Neurotrophic factors, Endocrinology, Programmed cell death and Nerve growth factor. Her study in Neurotrophin is interdisciplinary in nature, drawing from both Apoptosis and Receptor complex.

Her research investigates the connection with Receptor and areas like Immunology which intersect with concerns in Endothelial stem cell. Her studies deal with areas such as Brain-derived neurotrophic factor and Synaptic plasticity as well as Neuroscience. Her work carried out in the field of Trk receptor brings together such families of science as Ligand, Tyrosine kinase, Tropomyosin receptor kinase C, Molecular biology and Receptor tyrosine kinase.

She most often published in these fields:

  • Cell biology (55.81%)
  • Neurotrophin (43.02%)
  • Receptor (34.30%)

What were the highlights of her more recent work (between 2012-2021)?

  • Neuroscience (25.58%)
  • Cell biology (55.81%)
  • Neurotrophic factors (20.35%)

In recent papers she was focusing on the following fields of study:

Her main research concerns Neuroscience, Cell biology, Neurotrophic factors, Brain-derived neurotrophic factor and Receptor. In her work, Neurotrophin-3 is strongly intertwined with Nerve growth factor, which is a subfield of Neuroscience. Her work deals with themes such as Cell culture, Neurotrophin, Programmed cell death and HIF1A, which intersect with Cell biology.

She has included themes like Synaptic plasticity and Neuroprotection in her Neurotrophin study. She has researched Brain-derived neurotrophic factor in several fields, including Postsynaptic potential, Tropomyosin receptor kinase A, Immunology, Signal transduction and Tropomyosin receptor kinase B. Barbara L. Hempstead combines subjects such as Hippocampal formation and Growth cone with her study of Receptor.

Between 2012 and 2021, her most popular works were:

  • Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor (1231 citations)
  • proBDNF Negatively Regulates Neuronal Remodeling, Synaptic Transmission, and Synaptic Plasticity in Hippocampus (156 citations)
  • Autocrine BDNF–TrkB signalling within a single dendritic spine (155 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Genetics
  • Neuron

Her primary areas of study are Brain-derived neurotrophic factor, Cell biology, Neuroscience, Neurotrophic factors and Tropomyosin receptor kinase B. As a part of the same scientific family, Barbara L. Hempstead mostly works in the field of Brain-derived neurotrophic factor, focusing on Hippocampal formation and, on occasion, Neurogenesis and HEK 293 cells. Her Cell biology study deals with Cell culture intersecting with HIF1A.

Barbara L. Hempstead works mostly in the field of Neuroscience, limiting it down to concerns involving Synaptic plasticity and, occasionally, Immunology, Microglia and Signal transduction. Her Neurotrophic factors research is multidisciplinary, incorporating elements of Tropomyosin receptor kinase A, Nerve growth factor, Neuroplasticity and Endocrinology. Her Tropomyosin receptor kinase B research is multidisciplinary, relying on both Long-term potentiation, Low-affinity nerve growth factor receptor, Neurotrophin and Anatomy.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Regulation of cell survival by secreted proneurotrophins.

Ramee Lee;Pouneh Kermani;Kenneth K. Teng;Barbara L. Hempstead.
Science (2001)

2125 Citations

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

Christopher N. Parkhurst;Guang Yang;Ipe Ninan;Jeffrey N. Savas.
Cell (2013)

1931 Citations

The trk proto-oncogene product: a signal transducing receptor for nerve growth factor

David R. Kaplan;Barbara L. Hempstead;Dionisio Martin-Zanca;Moses V. Chao.
Science (1991)

1672 Citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor.

Barbara L. Hempstead;Dionisio Martin-Zanca;David R. Kaplan;Luis F. Parada.
Nature (1991)

1479 Citations

Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

Zhe-Yu Chen;Deqiang Jing;Kevin G. Bath;Alessandro Ieraci.
Science (2006)

1418 Citations

Variant Brain-Derived Neurotrophic Factor (BDNF) (Met66) Alters the Intracellular Trafficking and Activity-Dependent Secretion of Wild-Type BDNF in Neurosecretory Cells and Cortical Neurons

Zhe Yu Chen;Paresh D. Patel;Gayatree Sant;Chui Xiang Meng.
The Journal of Neuroscience (2004)

1187 Citations

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity.

Petti T. Pang;Petti T. Pang;Henry K. Teng;Eygene Zaitsev;Newton T. Woo.
Science (2004)

1182 Citations

Sortilin is essential for proNGF-induced neuronal cell death

Anders Nykjaer;Ramee Lee;Kenneth K. Teng;Pernille Jansen;Pernille Jansen.
Nature (2004)

1140 Citations

p75 and Trk: A two-receptor system

Moses V. Chao;Barbara L. Hempstead.
Trends in Neurosciences (1995)

1133 Citations

ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTR and Sortilin

Henry K. Teng;Kenneth K. Teng;Ramee Lee;Saundrene Wright.
The Journal of Neuroscience (2005)

1114 Citations

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