World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
115
Citations
55010
World Ranking
780
National Ranking
491

Medicine

D-Index
114
Citations
54897
World Ranking
4678
National Ranking
2540

Research.com Recognitions

  • 2011 - Member of the National Academy of Sciences
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2007 - Fellow of the American Academy of Arts and Sciences

Overview

Luis F. Parada is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research primarily focuses on biochemistry, genetics, molecular biology, and medicine, with notable subfields including molecular biology, genetics, neurology, oncology, and cancer research.

The main topics in their work encompass glioma diagnosis and treatment, single-cell and spatial transcriptomics, cancer cells and metastasis, neurofibromatosis and Schwannoma cases, sarcoma diagnosis and treatment, microRNA in disease regulation, and neurogenesis and neuroplasticity mechanisms.

The scientist has contributed extensively to publications, with frequent venues including bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Proceedings of the National Academy of Sciences, Neuro-Oncology, and Clinical Cancer Research.

Notable recent papers include:

  • Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy, 2022, Developmental Cell
  • Cell Lineage-Based Stratification for Glioblastoma, 2020, Cancer Cell
  • High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging, 2020, Proceedings of the National Academy of Sciences
  • Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [64Cu]Cu-NOTA-anti-CD8 PET, 2021, Clinical Cancer Research
  • Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression, 2021, Cell stem cell

Luis F. Parada has collaborated frequently with several coauthors, including:

  • Xuanhua Xie
  • Daochun Sun
  • Tejus Bale
  • Zilai Wang
  • Dan R. Laks

The scientist has been recognized by their peers with several awards, including being named a Member of the National Academy of Sciences in 2011, Fellow of the American Association for the Advancement of Science (AAAS) in 2008, and Fellow of the American Academy of Arts and Sciences in 2007.

Best Publications

  • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.

    Hartmut Land;Luis F. Parada;Robert A. Weinberg

  • A restricted cell population propagates glioblastoma growth after chemotherapy

    Jian Chen;Yanjiao Li;Tzong Shiue Yu;Tzong Shiue Yu;Renée M. McKay

  • The trk proto-oncogene product: a signal transducing receptor for nerve growth factor

    David R. Kaplan;Barbara L. Hempstead;Dionisio Martin-Zanca;Moses V. Chao

  • High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor.

    Barbara L. Hempstead;Dionisio Martin-Zanca;David R. Kaplan;Luis F. Parada

  • Cellular Oncogenes and Multistep Carcinogenesis

    Hartmut Land;Luis F. Parada;Robert A. Weinberg

  • TYROSINE PHOSPHORYLATION AND TYROSINE KINASE ACTIVITY OF THE TRK PROTO-ONCOGENE PRODUCT INDUCED BY NGF

    David R. Kaplan;Dionisio Martin-Zanca;Luis F. Parada

  • Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

    Luis F. Parada;Clifford J. Tabin;Chiaho Shih;Robert A. Weinberg

  • Pten Regulates Neuronal Arborization and Social Interaction in Mice

    Chang Hyuk Kwon;Bryan W. Luikart;Craig M. Powell;Jing Zhou

  • Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

    Luis F. Parada;Hartmut Land;Robert A. Weinberg;David Wolf

  • BDNF regulates eating behavior and locomotor activity in mice.

    Steven G. Kernie;Daniel J. Liebl;Luis F. Parada

  • The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain.

    Rüdiger Klein;Dorothy Conway;Luis F. Parada;Mariano Barbacid

  • Cryptorchidism in mice mutant for Insl3.

    Serge Nef;Luis F. Parada

  • Smad3 Mutant Mice Develop Metastatic Colorectal Cancer

    Yuan Zhu;James A Richardson;Luis F Parada;Jonathan M Graff

  • Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.

    Camilynn I. Brannan;Archibald S. Perkins;Kristine S. Vogel;Nancy Ratner

  • trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

    R. Klein;L.F. Parada;F. Coulier;M. Barbacid

  • Neurofibromas in NF1: Schwann Cell Origin and Role of Tumor Environment

    Yuan Zhu;Pritam Ghosh;Patrick Charnay;Dennis K. Burns

  • Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

    Yuan Zhu;Mario I. Romero;Pritam Ghosh;Zhengyi Ye

  • Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

    Sheila Alcantara Llaguno;Jian Chen;Chang Hyuk Kwon;Erica L. Jackson

  • Analysis of Hox gene expression in the chick limb bud

    C.E. Nelson;B.A. Morgan;A.C. Burke;E. Laufer

  • TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment (DOI: 10.1016/j.neuron.2008.06.023)

    Yun Li;Bryan W. Luikart;Shari G Birnbaum;Jian Chen

Frequent Co-Authors

Serge Nef
Serge Nef University of Geneva
Steven G. Kernie
Steven G. Kernie Columbia University
Lino Tessarollo
Lino Tessarollo National Institutes of Health
David H. Gutmann
David H. Gutmann Washington University in St. Louis
Pantelis Tsoulfas
Pantelis Tsoulfas University of Miami
D. Wade Clapp
D. Wade Clapp Indiana University
Feng Chun Yang
Feng Chun Yang The University of Texas Health Science Center at San Antonio
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center

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