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Rüdiger Klein

Rüdiger Klein

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Biology and Biochemistry
Germany
2023

D-Index & Metrics

Neuroscience

D-Index
108
Citations
52485
World Ranking
574
National Ranking
38

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Rüdiger Klein is affiliated with the Max Planck Society in Germany. Their research spans multiple fields within the life sciences, concentrating primarily on neuroscience and biochemistry, genetics, and molecular biology. Klein has contributed extensively to various subfields, including cellular and molecular neuroscience, molecular biology, social psychology, cell biology, and developmental neuroscience.

The scientist's main topics of work encompass genetic neurodegenerative diseases, neuroendocrine regulation and behavior, neuroscience and neuropharmacology research, axon guidance and neuronal signaling, neurogenesis and neuroplasticity mechanisms, receptor mechanisms and signaling, and memory and neural mechanisms.

Klein has published numerous papers in distinguished journals and venues. Recent publications include:

  • Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons (2020), Cell
  • The Insula Cortex Contacts Distinct Output Streams of the Central Amygdala (2020), Journal of Neuroscience
  • Fluc-EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease (2021), The EMBO Journal
  • Transcriptomics reveals amygdala neuron regulation by fasting and ghrelin thereby promoting feeding (2023), Science Advances
  • Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity (2021), Life Science Alliance

Their work has appeared frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), the Journal of Neuroscience, Science Advances, Nature Communications, and Life Science Alliance.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroscience
  • Science Advances
  • Nature Communications
  • Life Science Alliance

Klein has collaborated often with several researchers, indicating a range of ongoing partnerships. Frequent coauthors include Christian Peters, Federica Fermani, Irina Dudanova, Daniel del Toro, and Kerstin Voelkl.

  • Christian Peters
  • Federica Fermani
  • Irina Dudanova
  • Daniel del Toro
  • Kerstin Voelkl

Best Publications

  • Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

    Jens C. Brüning;Dinesh Gautam;Deborah J. Burks;Jennifer Gillette

  • Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

    François Tronche;Christoph Kellendonk;Oliver Kretz;Peter Gass

  • The trk proto-oncogene encodes a receptor for nerve growth factor.

    Rüdiger Klein;Shugian Jing;Venkata Nanduri;Edward O'Rourke

  • Mechanisms and functions of eph and ephrin signalling

    Klas Kullander;Rüdiger Klein

  • trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3.

    Fabienne Lamballe;Rüdiger Klein;Mariano Barbacid

  • Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor.

    Martin Gassmann;Franca Casagranda;Donata Orioli;Horst Simon

  • Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

    Ralf H. Adams;George A. Wilkinson;Cornelia Weiss;Francesca Diella

  • Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene

    Richard J. Smeyne;Rüdiger Klein;Andreas Schnapp;Linda K. Long

  • The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

    Rüdiger Klein;Venkata Nanduri;Shuqian Jing;Fabienne Lamballe

  • Essential Role for TrkB Receptors in Hippocampus-Mediated Learning

    Liliana Minichiello;Martin Korte;David Wolfer;Ralf Kühn

  • The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain.

    Rüdiger Klein;Dorothy Conway;Luis F. Parada;Mariano Barbacid

  • Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

    Rüdiger Klein;Richard J. Smeyne;Wolfgang Wurst;Linda K. Long

  • trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

    R. Klein;L.F. Parada;F. Coulier;M. Barbacid

  • Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

    Rüdiger Klein;Inmaculada Silos-Santiago;Richard J. Smeyne;Sergio A. Lira

  • Mechanisms of ephrin-Eph signalling in development, physiology and disease

    Artur Kania;Rüdiger Klein

  • Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System

    Mark Henkemeyer;Donata Orioli;Jeffrey T Henderson;Tracy M Saxton;Tracy M Saxton

  • β1-Class Integrins Regulate the Development of Laminae and Folia in the Cerebral and Cerebellar Cortex

    Diana Graus-Porta;Sandra Blaess;Mathias Senften;Amanda Littlewood-Evans

  • Essential Role of p38α MAP Kinase in Placental but Not Embryonic Cardiovascular Development

    Ralf H. Adams;Almudena Porras;Gema Alonso;Margaret Jones

  • Eph receptors and ephrins: effectors of morphogenesis

    Nigel Holder;Rüdiger Klein

  • The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3.

    Carlos Cordon-Cardo;Peter Tapley;Shuqian Jing;Venkata Nanduri

  • Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells.

    Nancy Y. Ip;Trevor N. Stitt;Peter Tapley;Rudiger Klein

Frequent Co-Authors

Liliana Minichiello
Liliana Minichiello University of Oxford
Klas Kullander
Klas Kullander Uppsala University
Riccardo Brambilla
Riccardo Brambilla Cardiff University
Tobias Bonhoeffer
Tobias Bonhoeffer Max Planck Society
Martin Korte
Martin Korte Technische Universität Braunschweig
Richard J. Smeyne
Richard J. Smeyne Thomas Jefferson University
Hans-Peter Lipp
Hans-Peter Lipp University of Zurich
Gary R. Lewin
Gary R. Lewin Max Delbrück Center for Molecular Medicine
Karl-Klaus Conzelmann
Karl-Klaus Conzelmann Ludwig-Maximilians-Universität München

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