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Biology and Biochemistry

D-Index
88
Citations
25996
World Ranking
2717
National Ranking
1408

Overview

Elena B. Pasquale is affiliated with the Discovery Institute in the United States and has a research focus spanning biochemistry, genetics, molecular biology, and neuroscience. Their work emphasizes several subfields including cellular and molecular neuroscience, molecular biology, cell biology, analytical chemistry, and pharmacology.

The scientist's research topics cover a diverse range of areas including:

  • Axon Guidance and Neuronal Signaling
  • Hippo pathway signaling and YAP/TAZ
  • Chromatography in Natural Products
  • Receptor Mechanisms and Signaling
  • Cell Adhesion Molecules Research
  • Protein Tyrosine Phosphatases
  • Signaling Pathways in Disease

Elena B. Pasquale has contributed to multiple research articles with notable publications such as:

  • "Eph receptors and ephrins in cancer progression," 2023, published in Nature reviews. Cancer
  • "Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex," 2020, Developmental Cell
  • "Ligand bias in receptor tyrosine kinase signaling," 2020, Journal of Biological Chemistry
  • "Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis," 2020, Journal of Neuroscience
  • "Noncanonical EphA2 Signaling Is a Driver of Tumor-Endothelial Cell Interactions and Metastatic Dissemination in BRAF Inhibitor-Resistant Melanoma," 2020, Journal of Investigative Dermatology

Frequent collaborators in their research include:

  • Kalina Hristova
  • Mike W. Matsumoto
  • Bernhard C. Lechtenberg
  • Marina P. Gehring
  • Elmer Zapata-Mercado

The primary venues publishing Elena B. Pasquale's research highlight journals such as the Journal of Biological Chemistry, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Biophysical Journal, and Developmental Cell.

Best Publications

  • Eph-ephrin bidirectional signaling in physiology and disease.

    Elena B. Pasquale;Elena B. Pasquale

  • Eph receptors and ephrins in cancer: bidirectional signalling and beyond

    Elena B. Pasquale

  • Eph receptor signalling casts a wide net on cell behaviour

    Elena B. Pasquale;Elena B. Pasquale

  • Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling.

    Keith K. Murai;Louis N. Nguyen;Fumitoshi Irie;Yu Yamaguchi

  • Tyrosine phosphorylation of transmembrane ligands for Eph receptors

    Katja Brückner;Elena B. Pasquale;Rüdiger Klein

  • Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.

    Vincent C Dodelet;Elena B Pasquale

  • Eph Receptor Signaling and Ephrins

    Erika M. Lisabeth;Giulia Falivelli;Giulia Falivelli;Elena B. Pasquale;Elena B. Pasquale

  • The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

    Kazushige Ogawa;Renata Pasqualini;Richard A Lindberg;Renate Kain

  • 'Eph'ective signaling: forward, reverse and crosstalk.

    Keith K. Murai;Elena B. Pasquale;Elena B. Pasquale

  • Molecular mechanisms of dendritic spine development and remodeling

    Iryna M. Ethell;Elena B. Pasquale

  • EphB/syndecan-2 signaling in dendritic spine morphogenesis.

    Iryna M. Ethell;Fumitoshi Irie;Matthew S. Kalo;John R. Couchman

  • The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl–Crk pathway

    Nicole K. Noren;Gabriele Foos;Craig A. Hauser;Elena B. Pasquale;Elena B. Pasquale

  • Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport.

    Alessandro Filosa;Sonia Paixao;Silke D. Honsek;Maria A. Carmona

  • Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth.

    Nicole K. Noren;Mark Lu;Andrew L. Freeman;Mitchell Koolpe

  • Eph receptors and ephrins: therapeutic opportunities.

    Antonio Barquilla;Elena B. Pasquale

  • Shared and distinct functions of RAGS and ELF‐1 in guiding retinal axons

    Bruno Monschau;Claus Kremoser;Kunimasa Ohta;Hideaki Tanaka

  • An Ephrin Mimetic Peptide That Selectively Targets the EphA2 Receptor

    Mitchell Koolpe;Monique Dail;Elena B. Pasquale

  • The Eph family of receptors

    Elena B Pasquale

  • An Eph receptor regulates integrin activity through R-Ras.

    June X. Zou;Bingcheng Wang;Bingcheng Wang;Matthew S. Kalo;Andreas H. Zisch;Andreas H. Zisch

  • Erratum: Eph receptor signalling casts a wide net on cell behaviour

    Elena B. Pasquale

Frequent Co-Authors

Keith K. Murai
Keith K. Murai McGill University Health Centre
Kalina Hristova
Kalina Hristova Johns Hopkins University
Maurizio Pellecchia
Maurizio Pellecchia University of California, Riverside
Yu Yamaguchi
Yu Yamaguchi Discovery Institute
Ziwei Huang
Ziwei Huang University of California, San Diego
Erkki Ruoslahti
Erkki Ruoslahti Sanford Burnham Prebys Medical Discovery Institute
Iryna M. Ethell
Iryna M. Ethell University of California, Riverside
Marie-Ève Tremblay
Marie-Ève Tremblay University of Victoria
Mark Bothwell
Mark Bothwell University of Washington
Xiao-Jing Wang
Xiao-Jing Wang University of California, Davis

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