World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
42
Citations
8629
World Ranking
19461
National Ranking
7937

Overview

Ziwei Huang is affiliated with the University of California, San Diego in the United States. Their research primarily explores the intersection of medicine and technology, with a notable focus on artificial intelligence applications, immunology, molecular biology, cognitive neuroscience, and computer vision and pattern recognition.

Their recent publications span a range of topics, publishing in various scientific journals. Noteworthy papers include: "A building regulation question answering system: A deep learning methodology" (2020) in Advanced Engineering Informatics, "Coptisine ameliorates DSS-induced ulcerative colitis via improving intestinal barrier dysfunction and suppressing inflammatory response" (2021) in European Journal of Pharmacology, "Type-specific dendritic integration in mouse retinal ganglion cells" (2020) in Nature Communications, "Formononetin improves cardiac function and depressive behaviours in myocardial infarction with depression by targeting GSK-3β to regulate macrophage/microglial polarization" (2022) in Phytomedicine, and "Reducing bias to source samples for unsupervised domain adaptation" (2021) in Neural Networks.

Ziwei Huang collaborates frequently with several researchers, including Philipp Berens, Thomas Euler, Yanli Ran, Jakob H. Macke, and Lisa M. Koch. These collaborative efforts reflect a multidisciplinary approach that spans neurological studies, computational modeling, and biomedical research.

The scholar has a consistent presence in several publication venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • arXiv (Cornell University)
  • PLOS Digital Health
  • The Journal of Open Source Software
  • Zenodo (CERN European Organization for Nuclear Research)

Ziwei Huang's research concentrates on several main topics of study, including:

  • Immunotherapy and Immune Responses
  • Neural dynamics and brain function
  • Retinal Imaging and Analysis
  • Retinal Development and Disorders
  • Acute Ischemic Stroke Management
  • Cell Image Analysis Techniques
  • Cancer Immunotherapy and Biomarkers

Their expertise extends deeply into fields of medicine, incorporating advanced AI techniques to interpret biological signals and mechanisms. Huang's work integrates complex neural dynamics and immune system behavior to address disorders related to the retina and stroke, as well as investigational cancer therapies.

Best Publications

  • Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

    Jia-Lun Wang;Dongxiang Liu;Zhi-Jia Zhang;Simei Shan

  • Molecular Determinants of the Caspase-promoting Activity of Smac/DIABLO and Its Role in the Death Receptor Pathway

    Srinivasa M. Srinivasula;Pinaki Datta;Xue-Jun Fan;Teresa Fernandes-Alnemri

  • XIAP mediates NOD signaling via interaction with RIP2

    Andreas Krieg;Ricardo G. Correa;Jason B. Garrison;Gaëlle Le Negrate

  • Structure-based virtual screening of chemical libraries for drug discovery.

    Sutapa Ghosh;Aihua Nie;Jing An;Ziwei Huang

  • Bcl-2 family proteins as targets for anticancer drug design

    Ziwei Huang

  • Cell Permeable Bcl-2 Binding Peptides: A Chemical Approach to Apoptosis Induction in Tumor Cells

    Jia-Lun Wang;Zhi-Jia Zhang;Swati Choksi;Simei Shan

  • Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias

    Zhihong Zeng;Ismael J. Samudio;Mark Munsell;Jing An

  • Generation of Constitutively Active Recombinant Caspases-3 and -6 by Rearrangement of Their Subunits

    Srinivasa M. Srinivasula;Manzoor Ahmad;Marion MacFarlane;Zhaowen Luo

  • Reactions of salicylaldehydes with alkyl cyanoacetates on the surface of solid catalysts: syntheses of 4H-chromene derivatives

    Niefang Yu;James M Aramini;Markus W Germann;Ziwei Huang

  • Structural and Functional Characterization of Human CXCR4 as a Chemokine Receptor and HIV-1 Co-receptor by Mutagenesis and Molecular Modeling Studies

    Naiming Zhou;Zhaowen Luo;Jiansong Luo;Dongxiang Liu;Dongxiang Liu

  • Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia

    Michele Milella;Zeev Estrov;Steven M. Kornblau;Bing Z. Carter

  • Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.

    Dayong Zhai;Chaofang Jin;Ziwei Huang;Arnold C. Satterthwait

  • Exploring the Stereochemistry of CXCR4-Peptide Recognition and Inhibiting HIV-1 Entry with d-Peptides Derived from Chemokines

    Naiming Zhou;Zhaowen Luo;Jiansong Luo;Xuejun Fan

  • Main chain and side chain chiral methylated somatostatin analogs : syntheses and conformational analyses

    Ziwei Huang;Ya Bo He;Karen Raynor;Melanie Tallent

  • Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells.

    Hirohito Yamaguchi;Shanthi R. Paranawithana;Michael W. Lee;Ziwei Huang

  • EC3, a Novel Heterodimeric Disintegrin from Echis carinatus Venom, Inhibits α4 and α5 Integrins in an RGD-independent Manner

    Cezary Marcinkiewicz;Juan J. Calvete;Mariola M. Marcinkiewicz;Manfred Raida

  • Structure-based discovery of small molecule inhibitors targeted to protein tyrosine phosphatase 1B.

    Mauro Sarmiento;Li Wu;‡ Yen-Fang Keng;Li Song

  • Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor.

    Jing An;Yingming Chen;Ziwei Huang

  • The chemical biology of apoptosis. Exploring protein-protein interactions and the life and death of cells with small molecules.

    Ziwei Huang

  • Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor

    J An;J An;A S Chervin;A Nie;H S Ducoff

Frequent Co-Authors

Robert Korngold
Robert Korngold Hackensack University Medical Center
Joseph Sodroski
Joseph Sodroski Harvard Medical School
John C. Reed
John C. Reed Johnson & Johnson (United States)
Elena B. Pasquale
Elena B. Pasquale Discovery Institute
Emad S. Alnemri
Emad S. Alnemri Thomas Jefferson University
Michael Andreeff
Michael Andreeff The University of Texas MD Anderson Cancer Center
Renato Baserga
Renato Baserga Thomas Jefferson University
Murray Goodman
Murray Goodman University of California, San Diego
Srinivasa M. Srinivasula
Srinivasa M. Srinivasula Indian Institute of Science Education and Research, Thiruvananthapuram
Marina Konopleva
Marina Konopleva The University of Texas MD Anderson Cancer Center

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